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171.
172.
Yanqiu Lu Shengquan Tang Yuanyuan Qin Vijay Harypursat Hao Wu Yaokai Chen 《中华医学杂志(英文版)》2022,135(22):2690
Background:A more comprehensive understanding of the trends of incidence, prevalence, and mortality in human immunodeficiency virus (HIV), and their complex interrelationships, may provide important evidence for decision-making related to HIV prevention and control. The variances in these indices between different population groups, genders, and ages are critical to decipher evolving patterns of the HIV epidemic in specific populations.Methods:A secondary analysis of relevant data was conducted using data extracted from the Global Burden of Disease study of 2019. HIV/acquired immune deficiency syndrome (AIDS) incidence, prevalence, AIDS-related mortality, and mortality-to-prevalence ratio (MPR) for annual percentage change, average annual percentage change (AAPC), and corresponding 95% confidence intervals (CIs) were calculated using joinpoint regression statistical analysis.Results:The AAPC of HIV/AIDS incidence, prevalence, AIDS-related mortality rate, and MPR were –1.4 (95% CI: –1.6, –1.2), 4.1 (95% CI: 4.0, 4.3), 2.0 (95% CI: 1.7, 2.3), and –2.1 (95% CI: –2.3, –1.8) between 1990 and 2019 globally, and were 3.5 (95% CI: 2.2, 4.8), 6.9 (95% CI: 6.8, 7.0), 8.1 (95% CI: 7.1, 9.1), and 1.2 (95% CI: 0.1, 2.3) in China during the same period. In terms of differences in the preceding indicators by gender, we observed a similar pattern of trends for male and female genders both globally and in China during the entire study period. Each specific age group exhibits a distinct pattern in terms of incidence, prevalence, mortality rate, and MPR both globally and in China.Conclusions:Prevalence and mortality rates of HIV/AIDS have increased between 1990 and 2019 globally and in China. While the incidence rate and MPR have declined globally over the past three decades, these two indicators are observed to present an increasing trend in China. There is a high HIV burden among young and middle-aged adults globally; however, the elderly have a high HIV burden in China. HIV screening at older age should be scaled up, and patients with advanced HIV disease should be provided early with additional care and health resources. 相似文献
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174.
目的:比较抑郁性神经症(ND)和重性抑郁症(MD)的临床特征的差异。方法:对符合CCMD-2-R诊断标准的30例ND和32例MD进行 对照分析。结果:两组患者在起病年龄、发病诱因、内向性格、阳性家族史、用药及转归方面均无显著性差异,在临床症状上的差异也仅表现在严重程度上。结论:ND具有心境障碍的性质。作者认为ND的分类学位置值得重新考虑。 相似文献