BackgroundTranscranial electric stimulation during MR imaging can introduce safety issues due to coupling of the RF field with the stimulation electrodes and leads.ObjectiveTo optimize the stimulation setup for MR current density imaging (MRCDI) and increase maximum stimulation current, a new low-conductivity (σ = 29.4 S/m) lead wire is designed and tested.MethodThe antenna effect was simulated to investigate the effect of lead conductivity. Subsequently, specific absorption rate (SAR) simulations for realistic lead configurations with low-conductivity leads and two electrode types were performed at 128 MHz and 298 MHz being the Larmor frequencies of protons at 3T and 7T. Temperature measurements were performed during MRI using high power deposition sequences to ensure that the electrodes comply with MRI temperature regulations.ResultsThe antenna effect was found for copper leads at ¼ RF wavelength and could be reliably eliminated using low-conductivity leads. Realistic lead configurations increased the head SAR and the local head SAR at the electrodes only minimally. The highest temperatures were measured on the rings of center-surround electrodes, while circular electrodes showed little heating. No temperature increase above the safety limit of 39 °C was observed.ConclusionCoupling to the RF field can be reliably prevented by low-conductivity leads, enabling cable paths optimal for MRCDI. Compared to commercial copper leads with safety resistors, the low-conductivity leads had lower total impedance, enabling the application of higher currents without changing stimulator design. Attention must be paid to electrode pads. 相似文献
A new alternating conjugated polymer (PTCDPP) of carbazole‐substituted triarylamine and diketopyrrolopyrrole is prepared and characterized in detail. The polymer exhibits two strong absorption bands at 345 and 600 nm. With highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energy levels of ?5.13 eV and ?3.67 eV, PTCDPP displays an energy gap of 1.66 eV. PTCDPP‐based bulk heterojunction solar cells with a structure of fluorinated tin oxide (FTO)/TiO2/PTCDPP:[6,6]‐phenyl‐C61‐butyric acid methyl ester (PCBM)/MoO3/Ag are fabricated. The devices are optimized by adjusting the composition of the PTCDPP:PCBM active layer, thermal treatment, and addition of processing additives. The device based on PTCDPP:PCBM (1:4, w/w) shows a power conversion efficiency (PCE) of 2.31%, with a short‐circuit current of 4.17 mA cm?2, an open‐circuit voltage of 0.79 V, and a fill factor of 0.35. The best cell performance (2.65% PCE) is achieved by using 1,8‐diiodooctane (3%, v/v) as a processing additive and annealing the active layer at 80 °C.
Bio-organic fertilizers based on biocontrol microorganisms have been widely applied to suppress soilborne diseases and improve crop yields. Studies on beneficial biocontrol agents have promoted the development of the bio-organic fertilizers in China. Our previous study demonstrated that a biocontrol agent, Erythrobacter sp. YH-07, can inhibit the growth of the plant pathogen Fusarium oxysporum. In the present study, we investigated the effects of this biocontrol agent on tomato wilt and used the illumina-based sequencing approach to characterize the variations in soil bacterial communities in a potted experiment. The aim of our study was to explore the potential correlation among bacterial communities, Fusarium wilt suppression, and soil properties after application of the biocontrol agent YH-07. The results showed that application of Erythrobacter sp. YH-07 effectively controlled outbreaks of tomato Fusarium wilt. The illumina MiSeq sequencing showed that Proteobacteria was the predominant phylum in the soil samples. Bacterial community composition and structure varied under different soil treatments, e.g., the relative abundance of Erythrobacter and Salinimicrobium was significantly increased in the YH treatment, and Acidobacteria were decreased in the YH treatment compared with the CK treatment. Additionally, the correlation results showed that the soil organic matter and available phosphorus and potassium were higher after YH-07 application, and they were positively correlated with bacterial community. The redundancy analysis showed Erythrobacter and Acidobacteria were the dominant genera after YH and CK treatments, respectively, and correlations with tomato Fusarium wilt incidence were negative and positive, respectively.The model plant tomato was used to verify the effect and mechanism of a novel discovered strain YH-07 which is a potential agent for biological control of soil borne disease named tomato Fusarium wilt. 相似文献
Ecotoxicology - The phytoplankton diversity and community response to physicochemical variables in mangrove zones of Guangdong Province along the South China coast was investigated from October to... 相似文献
Many complex behaviors that do not require learning are displayed and are termed innate. Although traditionally the subject matter of ethology,innate behaviors offer a unique entry point for neuroscientists to dissect the physiological mechanisms governing complex behaviors. Since the last century,converging evidence has implicated the hypothalamus as the central brain area that controls innate behaviors. Recent studies using cutting-edge tools have revealed that genetically-defined populations of neurons residing in distinct hypothalamic nuclei and their associated neural pathways regulate the initiation and maintenance of diverse behaviors including feeding,sleep,aggression,and parental care. Here,we review the newly-defi ned hypothalamic pathways that regulate each innate behavior. In addition,emerging general principles of the neural control of complex behaviors are discussed. 相似文献