胰腺癌组织微卫星DNA不稳定与肿瘤临床特征的相关性研究

胰腺癌组织微卫星ＤＮＡ不稳定与肿瘤临床特征的相关性研究李伟王殿昌李卫东王秀琴郝希山战忠利吴ＤＮＡ中微卫星序列的不稳定（ＭＩ）是发生在多种肿瘤细胞基因组中的分子事件之一［１］。我们选择消化道肿瘤尤其是胰腺癌相关基因附近的多态性位点，以ＰＣＲ方法扩增肿...     

针刺治疗持续性植物状态的临床研究

目的 观察针刺治疗持续性植物状态（PVS）的疗效。方法 对50例PVS患者运用针灸催醒及脑复苏后的系列症状对症治疗。结果与结论 针灸治疗PVS总有效率为82%。疗效与病程有很大关系，病程越长，有效率愈低；治疗在11－15个疗程者效果最佳，短疗程的治疗意义不大。     

中西医结合治疗急性病毒性心肌炎的临床观察

目的　总结全省 7家医院协作观察中西医结合和单纯西药治疗急性病毒性心肌炎(VMC)疗效。方法　 16 4例VMC患者随机分治疗组 (83例 )和对照组 (81例 ) ,分别采用中西医结合和单纯西药治疗。结果　治疗组肠道病毒RNA(EVs RNA)、柯萨奇病毒 (CVB) Ab和CVB IgM的转阴率明显优于对照组 (P值分别为 <0 0 1和 0 0 5 ) ,临床症状的好转 ,早搏、ST T的改善两组间无显著差异 (P >0 0 5 )。结论　目前对VMC西药无特殊治疗的情况下 ,可以采用中西医结合治疗     

中药槐米在美容防晒方面的开发研究

本研究室科研成果槐米精Ⅰ、Ⅱ防晒效果令人满意,优于现今普遍采用的化学合成防晒剂,更重要的是它是纯天然植物提取的活性物,用量小、成本低、无毒、无害、不致癌,而且兼有其他护肤莹面的良好功效。     

湖南省1996～1997年卫生总费用测算结果及初步分析

该分析了湖南省1996～1997年卫生总费用的筹资来源和分配流向,其中包括政府预算内卫生支出、社会卫生支出和居民个人卫生支出,并对卫生总费用进行了宏观分析。     

Cohort patterns in mortality trends among the elderly in seven European countries, 1950-99

BACKGROUND: Secular trends in old-age mortality are of crucial importance to population ageing. For the understanding and prediction of these trends, it is important to determine whether birth cohort effects, i.e. long-lasting effects of exposures earlier in life, are important in determining mortality trends up to old age. This study aimed to identify and describe cohort patterns in trends in mortality among the elderly (>60 years of age) in seven European countries. METHODS: A standard age-period-cohort analysis was applied to all-cause and cause-specific mortality data by 5-year age groups and sex, for Denmark, England and Wales, Finland, France, The Netherlands, Norway, and Sweden, in the period 1950-99. RESULTS: Cohort patterns were identified in all countries, for both the sexes and virtually all causes of death. They strongly influenced the trends in all-cause mortality among Danish, Dutch, and Norwegian men, and the trends in mortality from infectious diseases, lung cancer (men only), prostate cancer, breast cancer, and chronic obstructive pulmonary disease (COPD). All-cause mortality decline stagnated among Danish, Dutch, and Norwegian male birth cohorts born between 1890 and 1915, among French men born after 1920, and among women from all countries born after 1920. Where all-cause mortality decline stagnated, cohort patterns in mortality from lung cancer, COPD, and to a lesser extent ischaemic heart diseases, were unfavourable as well. For infectious diseases, stomach cancer, and cerebrovascular diseases, mortality increased among cohorts born before 1890, and decreased strongly thereafter. CONCLUSIONS: Cohort effects related to factors such as living conditions in childhood and smoking in adulthood were important in determining the recent trends in mortality among the elderly in seven European countries.     

Who visits mobile UK services providing cancer information and support in the community?

FOSTER C., SCOTT I. & ADDINGTON‐HALL J. (2010) European Journal of Cancer Care 19 , 221–226
Who visits mobile UK services providing cancer information and support in the community? People can access a variety of sources of information and support when they have questions about cancer according to their needs. There are various sources of information and support for cancer beyond the health‐care setting. In this study, we set out to assess reasons for visiting two mobile cancer information and support services in the UK during 2006. Data were collected about each visitor by staff on the mobile services. The two mobiles travelled to 109 UK locations over a 7‐month period. Fifty‐nine per cent of visitors were women. Thirty‐one per cent of visitors had (had) cancer; very few were still undergoing treatment. For 95% of visitors the visit had been spontaneous rather than pre‐planned, and 89% of visits lasted <15 min. Most visitors required information or support for themselves, but a third requested information for someone else. A quarter of enquiries were about cancer prevention and early detection (e.g. screening, genetic testing, lifestyle). The mobiles appear to serve an important function in providing information and support in the community where visitors can drop in for an informal conversation with trained members of staff to ask questions and receive support in relation to cancer.