Treatment of hemophilia A by living mother-to-son splenic transplantation. First case report in the world.

A case of severe hemophilia A was treated by living mother-to-son splenic transplantation. The recipient was a 9-year-old boy. After splenic transplantation, the level of blood factor VIII:C was increased, and no spontaneous hemorrhage occurred. The boy was followed up for over two years. This is a case of spleen allotransplantation with the longest function in the world.

     

Clinical report of cervical arthroplasty in management of spondylotic myelopathy in Chinese

Objectives  

To investigate clinical effects and manual operational point of Bryan cervical disc prosthesis in Chinese, to observe the stability and range of movement (ROM) post-operatively.     

一种血吸虫病兔肝原色保存方法

为了更好地观察血吸虫病肝脏虫卵肉芽肿病理变化的特征,必须保持肝脏原有颜色。以前常有2种保存标本的方法:第1种方法是把新鲜肝脏直接放入10%甲醛液内,保存时间长,但肝脏会变成与灰白色虫卵肉芽肿颜色近似,对比度降低,影响观察;第2种方法是用甲醛、过硫酸钠、蒸溜水、吡啶配方     

全胃切除ρ形空肠代胃治疗胃癌64例报告

报告全胃切除ρ形空肠代胃治疗胃癌６４例。术后无吻合口瘘与手术死亡，无返流性食管炎和倾倒综合征，生存质量满意。术后１、３、５年生存率分别为７１．８％、４２．２％和３４．４％。本组结果表明：此种改良后的ρ形空肠代胃、空肠原位间置术式，安全、简便、省时，使常见的手术并发症和远期后遗症均可得到较好预防和纠正，术后生存质量高，是一种满意的代胃术。     

Segmental fixation with U-shaped rod in the treatment of spondylolisthesis

Summary From 1987 to 1990 the authors treated 20 cases of spondylolisthesis by an improved operative procedure including excision of the medial part of the superior articular processes of the slipped vertebra, excision of the soft tissue between the ununited isthmi, and excision of the ligamentum flavum between the intervertebral space above the slipped segment. In some instances the lower portion of the lamina over the slipped vertebra should be resected. A U-shaped rod was used to hold sublaminar fixation of two segments above and below the slipped vertebra, with the slipped vertebra spared. Utilizing the U-shaped rod as support, bone strips were placed along the lateral and anterior sides of the rod to bridge the gap between the laminae of the displaced vertebra. Other bone grafts were focused on the facet joints. The patients were allowed ambulation early postoperatively. 19 cases could be evaluated at preliminary follow-up. All showed satisfactory results.     

Experimental study of the effect on the liver of cortisol after diverting the adrenal venous circulation into the portal circulation

In order to evaluate the operation of the adrenal autotransplantation into omentum with arterio-venous anastomosis, the right adrenal of fifteen dogs was preliminarily removed and then the left adrenal vein was diverted into the portal circulation by micro surgical technique. Before and after the diversion, the serum cortisol taken from portal vein, hepatic vein, inferior vena cava and peripheral vein was analysed by radioimmunoassay. The dog's adrenal cortex, pituitary were removed for light and electron-microscopic examination. The experimental results demonstrate that the cortisol inactivation effect of the liver was not statistically different before and after the procedure (P greater than 0.05). Thus, we believe that the omentum which has obvious absorbability and revascularity is a reasonable site for adrenal transplantation. And we also found the adrenal cortex left appear slight hypotrophy and pituitary hypertrophy after the diversion. The cause however, requires further research.     

Local cerebral blood flow responses in rats to hypercapnia and hypoxia in the rostral ventrolateral medulla and in the cortex.

The effects of hypercapnia and hypoxia on two local cerebral blood flows in the parietal cortex (PC-BF) and rostral ventrolateral medulla (RVLM-BF) were examined using laser Doppler flowmetry in anesthetized rats. Hypercapnia for 45 s duration at the end-tidal CO2 between 5% and 10%, induced by increasing inspiratory CO2, increased both cerebral blood flows and systemic blood pressure in a degree-dependent manner. The response of RVLM-BF was significantly stronger than that of PC-BF. Both cerebral blood flow responses to hypercapnia were not influenced by cutting peripheral chemoreceptor afferent nerves. Hypoxia for 45 s duration at the end-tidal O2 between 12% and 6%, induced by decreasing inspiratory O2, produced an increase of similar magnitude in both RVLM and PC local blood flows in a degree-dependent manner and a decrease in systemic blood pressure. The responses of both PC-BF and RVLM-BF to hypoxia were significantly diminished after cutting peripheral chemoreceptor afferent nerves. It is concluded that: (1) the RVLM-BF is much more sensitive to hypercapnia than the PC-BF; and (2) activation of peripheral arterial chemoreceptors possibly contributes to hypoxia-induced increase in the RVLM-BF and PC-BF.