全文获取类型
收费全文 | 173960篇 |
免费 | 12121篇 |
国内免费 | 6145篇 |
专业分类
耳鼻咽喉 | 2099篇 |
儿科学 | 3472篇 |
妇产科学 | 4621篇 |
基础医学 | 24627篇 |
口腔科学 | 4412篇 |
临床医学 | 17028篇 |
内科学 | 29540篇 |
皮肤病学 | 2863篇 |
神经病学 | 10933篇 |
特种医学 | 6129篇 |
外国民族医学 | 47篇 |
外科学 | 21976篇 |
综合类 | 15225篇 |
现状与发展 | 7篇 |
一般理论 | 39篇 |
预防医学 | 12445篇 |
眼科学 | 4222篇 |
药学 | 16311篇 |
64篇 | |
中国医学 | 4389篇 |
肿瘤学 | 11777篇 |
出版年
2023年 | 1212篇 |
2022年 | 2845篇 |
2021年 | 3774篇 |
2020年 | 2762篇 |
2019年 | 2934篇 |
2018年 | 3602篇 |
2017年 | 2916篇 |
2016年 | 2914篇 |
2015年 | 4120篇 |
2014年 | 4965篇 |
2013年 | 5057篇 |
2012年 | 7544篇 |
2011年 | 8115篇 |
2010年 | 5042篇 |
2009年 | 4133篇 |
2008年 | 6131篇 |
2007年 | 6440篇 |
2006年 | 6470篇 |
2005年 | 5857篇 |
2004年 | 5016篇 |
2003年 | 5028篇 |
2002年 | 4614篇 |
2001年 | 8391篇 |
2000年 | 8311篇 |
1999年 | 7003篇 |
1998年 | 2795篇 |
1997年 | 2269篇 |
1996年 | 1599篇 |
1995年 | 1544篇 |
1994年 | 1383篇 |
1993年 | 1066篇 |
1992年 | 4098篇 |
1991年 | 4097篇 |
1990年 | 3784篇 |
1989年 | 3775篇 |
1988年 | 3582篇 |
1987年 | 3395篇 |
1986年 | 3198篇 |
1985年 | 3042篇 |
1984年 | 2079篇 |
1983年 | 1819篇 |
1979年 | 1919篇 |
1978年 | 1186篇 |
1975年 | 1191篇 |
1974年 | 1358篇 |
1973年 | 1413篇 |
1972年 | 1357篇 |
1971年 | 1247篇 |
1970年 | 1137篇 |
1969年 | 1121篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
92.
93.
Z. Malazgirt K. Topgul S. Sokmen S. Ersin A. G. Turkcapar H. Gok N. Gonullu M. Paksoy M. Ertem 《Hernia》2006,10(4):326-330
Most of the papers published on spigelian hernia are either case reports or small retrospective series. In this prospective
multicenter study, we aimed to outline the specific features of spigelian hernias and patients’ characteristics more clearly.
Surgeons enrolled patients to be entered into the database as they diagnosed and treated the hernias at will. The baseline
and surgical outcome parameters were noted in each patient. A painful mass was the main presenting complaint in half of 34
patients. Accurate preoperative diagnosis was possible in 31 patients. Open intraperitoneal mesh repair was the preferred
technique. The mean hospital stay and time until return to normal daily activities were 4.1 and 15.6 days. Although a rare
condition, diagnosis of a spigelian hernia is not difficult once remembered. Its surgical repair seems to cause few complications
and is very well tolerated by the patient. 相似文献
94.
目的:探讨急性重症胆管炎患者的手术时机和死亡原因。方法:回顾性分析23例急性重症胆管炎患者的治疗及预后情况。结果:死亡2例(手术死亡及传统治疗死亡各1例)。早期大剂量短期应用糖皮质激素患者休克得到纠正率85%,明显高于未用糖皮质激素患者休克纠正率50%。结论:急性重症胆管炎患者应在出现休克和(或)精神症状之前手术,对已出现休克的患者,应先给予充分的保守治疗,待病情稳定后再手术。贻误手术时机,严重合并症如多器官功能衰竭及高龄是死亡的主要原因。 相似文献
95.
Human exposure to 3-carene by inhalation: toxicokinetics, effects on pulmonary function and occurrence of irritative and CNS symptoms 总被引:5,自引:0,他引:5
Terpenes, especially 3-carene, may irritate the skin and mucous membranes and prolonged exposure may result in allergic contact dermatitis or chronic lung function impairment. The toxicokinetics of 3-carene were studied in human volunteers exposed by inhalation (2 hr 50 W) in an exposure chamber on three occasions. The exposure concentrations were approximately 10, 225, and 450 mg/m3 3-carene. The relative pulmonary uptake was high, approximately 70% for the higher exposure levels. Total uptake increased linearly with increasing exposure. The blood clearance of 3-carene observed in this study, 0.9 liter.kg-1.hr-1, indicates that 3-carene is fairly readily metabolized. About 3% of the total uptake was eliminated unchanged via the lungs while less than 0.001% was eliminated in the urine after the end of exposure. A long half time in blood was observed in the terminal phase which indicates a high affinity to adipose tissues. A statistically significant divergence between ratings of irritation during the high exposure level and during the medium and control levels was observed. The difference in airway resistance after exposure to a high concentration of 3-carene compared to control level was not significant (P = 0.02). 相似文献
96.
Single or combined monoclonal antibodies (McAbs) Zh53, Zh820, and Zh2-1 have been used to eliminate malignant clonogenic cells from human bone marrow. The test of cytotoxicity showed that all of these McAbs could express high specific cytotoxic action against HL-60 cells and were selectively complement-dependent cytotoxic to various types of fresh leukemic cells. Clonogenic assay detected that single treatment with antibody and rabbit complement (RC) could reduce clonogenic units of HL-60 cells by more than 2 logs and two treatments reduced clonogenic units by more than 4 logs. However, combination of 2 McAbs could reduce clonogenic units by 4-5 logs. The data suggest that multiple treatments with McAbs and RC or a combination of 2 McAbs are more effective than a single treatment in eliminating clonogenic tumor cells. Treatment of normal human bone marrow with Zh53, Zh2-1 and RC did not produce a loss of normal CFU-GM, but treatment with Zh820 reduced the clonic units of normal CFU-GM by 24%.
相似文献
97.
Cancer mortality in the elderly has rarely been analyzed. It is most notably characterized by the level of diagnostic accuracy at ages prone to comorbidities. Trend analysis over the last thirty years and disparities in mortality have underscored the increasing cancer mortality in the over-65 age bracket as well as the relevance of local health context in understanding the significant differences seen throughout France. 相似文献
98.
化疗药物配制方法探讨 总被引:10,自引:0,他引:10
为探讨化疗药物正确的配制方法,有效地预防化疗药物可能存在的职业危害,并使病人得到准确的用药剂量。提出配制化疗药物应在专门的化疗药物配制阃配制,使用特制的层流净化操作台,不具备条件者可在排风设备良好、空气流通的场所内配制。配制人员必须熟练掌握化疗药物的药理知识,配制时应严格做好查对工作。 相似文献
99.
J Thornton D M Ashcroft M Z Mughal R A Elliott T W O'Neill D Symmons 《Archives of disease in childhood》2006,91(9):753-761
AIMS: To evaluate the currently available evidence for the effectiveness of bisphosphonates in children with low bone mineral density (BMD) and fragility fractures associated with juvenile idiopathic arthritis (JIA), and the safety of bisphosphonates in JIA and other conditions. METHODS: Literature databases were searched using a structured search strategy. The effectiveness review included any studies of children with JIA treated with bisphosphonates. The safety review also included studies of osteogenesis imperfecta. Quantitative data analysis was not undertaken because of the heterogeneity of the studies; findings were summarised using tables and narrative synthesis. RESULTS: Ninety four studies were identified. Sixteen studies (78 JIA children) were included in the effectiveness review: one randomised controlled trial, three controlled cohort studies, 11 case series, and one case report. At baseline, children had low BMD below the expected values for age and sex matched children. In all studies, treatment with bisphosphonates increased BMD compared with baseline: the mean percentage increase in spine BMD ranged from 4.5% to 19.1%. Overall, studies were heterogeneous and of variable quality. A total of 59 papers were included in the safety review; treatment durations were up to three years. The most common side effect was a flu-like reaction with intravenous treatment. This occurred during the first infusion and was transient; the symptoms were managed with paracetamol and did not occur during subsequent cycles. CONCLUSIONS: Bisphosphonates are a promising treatment for low BMD and fragility fractures in children with JIA. However, the quality of the current evidence is variable and better studies are needed to more clearly assess their role. 相似文献
100.
听力对语言影响的表现与矫正 总被引:1,自引:1,他引:0
郭金美 《中国听力语言康复科学杂志》2005,(2):42-44
目的 通过对302例药物致聋聋儿的临床观察,研究听力对语言影响的表现,从中摸索积极的矫正补偿方法,使聋儿能听会说,早日回归主流社会。方法:根据听力损失以1/2增益法,选择不同型号的助听器,用具有频率特性的玩具进行适应性训练,采用视觉强化测听法和言语测听法,调整助听器增益,努力使各频率尽可能进入言语香蕉图。结果 100%聋儿表现听觉的敏感性和言语的清晰度低,且存在不同程度的“重振”;聋儿助听补偿效果越好,语言清晰度越高;聋儿只能在信噪比>10 dB SPL的情况下才能听懂语言;言语识别中存在有不同种类的掩蔽现象;双耳配戴助听器对言语接受阈能提高约15%左右。结论:双耳配戴助听器以及利用助听器的微调和耳模的声学作用来改变助听器的频响,选择电脑编程、全数字、带有“AGC”功能、带有指向性麦克风等不同功能的助听器,都是十分有效的矫正措施;选择信噪比≥10 dB SPL的学习环境;充分利用视觉、触觉功能补偿作用;努力学习好辅音;教师正确控制语音、语速、声调、掌握抑扬顿挫,防止声音向上、向后、向前掩蔽。 相似文献