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991.
Yoshiki Kajiya Hisashi Kobayashi Masayuki Nakajo 《Cardiovascular and interventional radiology》1993,16(3):150-157
Transarterial internal radiation with I-131 Lipiodol (TAIR) was performed in 21 patients with multifocal hepatic carcinoma.
Eight patients were treated by TAIR alone and 13 by combination of TAIR and intraarterial infusion ofcis-diamminedichloroplatinum (CDDP) and/or adriamycin mitomycin C oil suspension (ADMOS). TAIR was found effective immediately
and long-term. Serum α-fetoprotein (AFP) levels dropped to 50% or less in 7 of 14 patients. Eleven of 21 patients (52%) showed
50% or greater decrease in tumor size. The overall 1-year survival rate was 43% and 67% in patients who received 50 Gy or
greater tumor dose. Lipiodol distribution pattern of the tumor indicated some difference in the prognosis between the scattered
pattern and solid pattern. The solid pattern showed a statistically significant better survival rate. Patients treated with
TAIR alone versus those treated with TAIR and chemotherapy showed no difference in their survival rate. 相似文献
992.
Nobuaki Hirata Shigeaki Ohtake Yoshiki Sawa Motonobu Nishimura Yoshitaka Hayashi Hikaru Matsuda 《General thoracic and cardiovascular surgery》1998,46(12):1226-1228
Simultaneous minimally invasive direct coronary artery bypass and abdominal aortic aneurysm repair were conducted in a 66-year-old man uneventful, requiring no transfusion. Surgery required 9 hours and 2 minutes. The tracheal tube was extubated in the operating room. Postoperative bleeding was 215 ml. The postoperative course was very smooth, with the patient able to walk on postoperative day 1. Postoperative coronary arteriogram and aortogram showed favorable results and the patient was discharged on day 23 after surgery. 相似文献
993.
Rintaro Mori Shinji Yamakura Hiroyuki Tanaka Hiroshi Tamai Masahisa Funato Yoshiki Seino 《Journal of bone and mineral metabolism》1998,16(2):100-105
We assessed the bone status of preterm and term infants by measuring their bone mineral density (BMD) by dual-energy X-ray
absorptiometry (DXA). Thirty neonates weighing 699–3590 g were selected as subjects. Infants with multiple anomalies or severe
chronic lung disease were excluded. Using the corrected term age (35–48 weeks), we measured their lumbar spinal BMD (L1–L4)
by DXA. Alkaline phosphatase (ALP) and skeletal alkaline phosphatase (B-ALP) were measured at the same time. In addition,
we compared the BMD values with growth parameters and chemical markers. The term BMD correlated significantly with the birth
weight (r = .90), height (r = .85), and gestational age (r = .76). The birth weight correlated more closely with the BMD than with the weight at the time of BMD measurement. The B-ALP
level showed an inverse correlation with BMD (r = −0.41). The preterm infants apparently acquired lower BMDs during intrauterine life. The inverse correlation of B-ALP with
BMD may be found only in the neonatal period. The BMD measured by DXA and the B-ALP level are very useful parameters for assessing
bone status in infants, including extremely low birth weight infants.
Received: Aug. 21, 1997 / Accepted: Nov. 6, 1997 相似文献
994.
995.
Takami Miki M.D. Hiroaki Yoshida Atsushi Shioi Shuichi Jono Mitsuya Yoshino Kiyoshi Nakatsuka Satoshi Hagiwara Takahiko Kawagishi Yoshiki Nishizawa Hirotoshi Morii 《Journal of bone and mineral metabolism》1993,11(2):39-44
We investigated the changes of natural type of interferon-α (IFNα) on calcium and bone metabolism in patients with chronic hepatitis C. Natural IFNα was injected intramuscularly at daily doses of 6 million units for 2 weeks to 10 patients with chronic hepatitis caused by
hepatitis C virus, and followed by 3-times-a-week administration for another 10 weeks. The markers for bone metabolism including
serum bone-Gla protein (BGP) concentration and urinary excretion of pyridinolines (pyridinoline and deoxypyridinoline) were
measured before and during the treatment. The twelve-week administration of IFNα reduced pyridinoline excretion from 39.7±13.3 (SD) pmol/μ mol · creatinine to 28.3±8.1 pmol/μ mol · creatinine (p<0.06), and that of deoxypyridinoline from 6.51±3.38 pmol/μ mol · creatinine to 3.91±2.07 pmol/μ mol · creatinine (p<0.01), although serum levels of BGP and parathyroid hormone (PTH) did not show any significant changes.
The ratio of BGP/urinary pyridinoline increased from 0.098±0.074 to 0.198±0.093 at the end of 12th week (p<0.03), and that
of BGP/deoxypyridinoline increased from 0.630±0.502 to 1.550±0.788 at 12th week (p<0.02). Serum aspartate transaminase (AST),
alanine transaminase (ALT), and alkaline phosphatase (ALP) did not change significantly during the study.
IFNα reduces bone resorption in contrast with insignificant effects on bone formation in patients with mild to moderate hepatitis.
The effects on calcium and bone metabolism may give beneficial effects for patients with high turnover osteoporosis. 相似文献
996.
The effects of psoriatic sera were investigated on the generation of oxygen intermediates (OIs) by normal polymorphonuclear leucocytes (PMNs). Although increased superoxide generation was noted, a further respiratory burst of the PMns was significantly suppressed. Since superoxide dismutase (SOD) and catalase activities of the sera assayed in the xanthine-xanthine oxidase system were comparable to the controls, it still remains obscure why this dissociation occurs. It is suggested that increased generation of superoxide anion from the PMNs may be another facet of PMN activation which plays an important role in the psoriatic process. 相似文献
997.
Effect of age and strain on N-methyl-N'-nitro-N-nitrosoguanidine tumorigenesis in ACI and Wistar Furth rats 总被引:3,自引:0,他引:3
Watanabe Hiromitsu; Nakagawa Yoshiki; Takahashi Tadateru; Ito Akihiro 《Carcinogenesis》1988,9(7):1317-1318
N-Methyl-N'-nitro-N-nitrosoguanidine (MNNG) dissolved indistilledwater (5 g/1) was administered orally once by gastrictube ata dose of 0.25 ml/10 g body weight to 5-day-old or 28-day-oldWistar Furth (W/Fu) or ACI rats. Gastric tumorsin the glandularstomach were found in 58% of 5-day-old ACI rats, but none werefound in the rest of the groups. Forestomach tumors were foundin both strains of rats at bothage groups with incidences of68100%. Lung tumors wereinduced in 64% of 5-day-old and6% of 28-day-old W/Fu rats,but not in ACI rats. Besides thetumors, a high frequency of hepatic cysts was also noted inACI rats. Intestinal metaplastic foci with alkaline phosphataseactivity were foundin the group of 5-day-old ACI rats and nonein the rest ofthe groups. The results showed that the incidencesand thelocations of tumors in rats induced by MNNG are greatlyinfluencedby both strain and age. 相似文献
998.
999.
Kazuo Uemura Nils Sternby Rudolf Vaně?ek Anatoli Vihert Aubrey Kagan 《Bulletin of the World Health Organization》1964,31(3):297-3201
A method of assessing “atherosclerosis”, if used according to certain rules, was shown in an earlier study to be capable of discriminating between groups of aortas or coronary arteries according to the quantity of certain defined lesions. It would not measure absolute amounts, but would show whether one group of specimens had more or less of the factor assessed than another and would indicate the statistical significance of this finding according to the number of specimens in each group. 相似文献
1000.
S Miura I Kanno H Iida M Murakami K Takahashi H Sasaki A Inugami F Shishido T Ogawa K Uemura 《Journal of computer assisted tomography》1988,12(2):363-367
We have developed a method that allows us to place regions of interest on X-ray CT (XCT) images that are automatically adjusted to positron emission tomography (PET) images from the same patient. A face mask with landmarks was used during PET and XCT studies for matching slice positions between PET and XCT. Anatomical locations in different images of the same slice can be accurately adjusted using the landmarks and a video system. In our clinical experience misadjustments of the slice position are on the average less than 2 mm in axial distance and 1.0 degrees in slice angle. The method is easily applicable to any PET or XCT device. 相似文献