全文获取类型
收费全文 | 3341篇 |
免费 | 178篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 72篇 |
妇产科学 | 87篇 |
基础医学 | 418篇 |
口腔科学 | 101篇 |
临床医学 | 196篇 |
内科学 | 780篇 |
皮肤病学 | 147篇 |
神经病学 | 307篇 |
特种医学 | 84篇 |
外科学 | 582篇 |
综合类 | 14篇 |
预防医学 | 90篇 |
眼科学 | 54篇 |
药学 | 227篇 |
中国医学 | 8篇 |
肿瘤学 | 349篇 |
出版年
2022年 | 32篇 |
2021年 | 61篇 |
2020年 | 24篇 |
2019年 | 32篇 |
2018年 | 52篇 |
2017年 | 32篇 |
2016年 | 58篇 |
2015年 | 56篇 |
2014年 | 75篇 |
2013年 | 88篇 |
2012年 | 131篇 |
2011年 | 144篇 |
2010年 | 94篇 |
2009年 | 90篇 |
2008年 | 145篇 |
2007年 | 177篇 |
2006年 | 161篇 |
2005年 | 176篇 |
2004年 | 149篇 |
2003年 | 204篇 |
2002年 | 186篇 |
2001年 | 127篇 |
2000年 | 107篇 |
1999年 | 100篇 |
1998年 | 34篇 |
1997年 | 38篇 |
1996年 | 30篇 |
1995年 | 26篇 |
1994年 | 28篇 |
1993年 | 35篇 |
1992年 | 94篇 |
1991年 | 89篇 |
1990年 | 67篇 |
1989年 | 61篇 |
1988年 | 43篇 |
1987年 | 52篇 |
1986年 | 47篇 |
1985年 | 55篇 |
1984年 | 48篇 |
1983年 | 40篇 |
1982年 | 13篇 |
1980年 | 16篇 |
1979年 | 36篇 |
1978年 | 14篇 |
1977年 | 15篇 |
1976年 | 14篇 |
1972年 | 14篇 |
1971年 | 23篇 |
1970年 | 11篇 |
1967年 | 13篇 |
排序方式: 共有3529条查询结果,搜索用时 359 毫秒
101.
Nobuhiro Yoshijima Ryo Yanagisawa Hiromu Hase Makoto Tanaka Hikaru Tsuruta Hideyuki Shimizu Keiichi Fukuda Toru Naganuma Kazuki Mizutani Motoharu Araki Norio Tada Futoshi Yamanaka Shinichi Shirai Minoru Tabata Hiroshi Ueno Kensuke Takagi Akihiro Higashimori Yusuke Watanabe Masanori Yamamoto Kentaro Hayashida 《Catheterization and cardiovascular interventions》2020,95(1):35-44
102.
Tomomi Fujisawa Chisato Tawada Yoko Mizutani Tomoaki Doi Shozo Yoshida Shinji Ogura Mariko Seishima 《Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy》2014,18(3):238-243
Palmoplantar pustulosis (PPP) is characterized by neutrophilic pustules with erythema, which are limited to the hands and feet. Although granulocyte and monocyte adsorption apheresis (GMA) has shown remarkable effects on generalized pustular psoriasis, there are few reports of PPP treated with GMA. We treated three refractory PPP patients using GMA weekly for 5 weeks. The skin eruptions were assessed by a 5‐grade score for scales, pustules, and erythema. GMA decreased the total grade from 9 to 2 in patients 1 and 2, and from 7 to 3 in patient 3. The GMA effects were estimated to be excellent in all three patients. Pustule formation and pain disappeared in all cases. The treatment effect lasted for at least 5 months after GMA. GMA was also effective for relieving the arthralgia in one patient, but it recurred at 6 weeks. Based on these findings, GMA could be an effective therapy for refractory PPP. 相似文献
103.
104.
105.
Kiyota M Kobayashi T Fuchida S Yamamoto-Sugitani M Ohshiro M Shimura Y Mizutani S Nagoshi H Sasaki N Nakayama R Chinen Y Sakamoto N Uchiyama H Matsumoto Y Horiike S Shimazaki C Kuroda J Taniwaki M 《International journal of hematology》2012,95(5):516-526
We retrospectively investigated the prognostic impact of high-risk cytogenetic abnormalities (CAs) on the outcome of treatment with bortezomib plus dexamethasone (BD) in 43 relapsed/refractory (Rel/Ref) multiple myeloma patients. Fluorescence in situ hybridization (FISH) analysis identified del(13q) in 25 patients, t(4;14) in 14, t(14;16) in 4, 1q21 abnormality in 12 and del(17p) in 2, while G-banding also detected chromosome 13 monosomy (-13) in metaphase spreads from 7 patients. Eighteen of 25 patients with FISH-detected chromosome 13 abnormalities also exhibited other abnormalities. Median observation period was 510 days, and median overall survival (OS) and progression-free survival (PFS) were 912 days and 162 days, respectively. Detection of del(13q), t(4;14), t(14;16) or 1q21 abnormalities by FISH and co-occurrence of chromosome 13 abnormality with other abnormalities were not associated with poorer outcomes. In contrast, detection of -13 by G-banding in metaphase spreads showed significant association with shorter OS, although the overall response rate and PFS were not inferior to those for patients without -13 detected by G-banding. BD therapy may be a potent weapon for overcoming most classical high-risk CAs, while the detection of -13 in metaphase spreads may serve as a predictor of highly progressive disease, even when treated with BD. 相似文献
106.
Hidenori Arai Yasuyoshi Ouchi Masayuki Yokode Hideki Ito Hiroshi Uematsu Fumio Eto Shinichi Oshima Kikuko Ota Yasushi Saito Hidetada Sasaki Kazuo Tsubota Hidenao Fukuyama Yoshihito Honda Akihisa Iguchi Kenji Toba Takayuki Hosoi Toru Kita for the Members of the Subcommittee for Aging 《Geriatrics & Gerontology International》2012,12(1):16-22
107.
108.
109.
Kihara Y Satho T Eshita Y Sakai K Kotaki A Takasaki T Rongsriyam Y Komalamisra N Srisawat R Lapcharoen P Sumroiphon S Iwanaga S Ushijima H Endoh D Miyata T Sakata A Kashige N Miake F Fukushi S Saijo M Kurane I Morikawa S Mizutani T 《Journal of virological methods》2007,146(1-2):372-374
A method for rapid determination of viral RNA sequences (RDV) was applied to homogenates of Aedes aegypti collected in Thailand in an area in which dengue fever (dengue hemorrhagic fever) is endemic, using the mosquito cell line C6/36. Nucleic acid sequences of dengue virus type 4 and cell fusing agent virus were detected. This RDV method has the potential to become a standard method for detection of both known and newly emerging, unknown mosquito-borne viruses. 相似文献
110.