Lipofibromatous Hamartoma of the Median Nerve Associated with Macrodactyly and Port-Wine Stains

Abstract: Lipofibromatous hamartoma of the nerve is a very uncommon congenital tumor. An association between this condition and vascular malformations is not well known. We present an 11 -year-old girl with a lipofibromatous hamartoma of the right median nerve with macrodactyly. She had small red macules on her right neck, chest, and arm, which were diagnosed clinically as port-wine stains. The specimens of the enlarged nerves showed fibrous and fatty growth surrounding the nerve bundles and proliferation of the small veins. We suggest that this disorder can be accompanied by a vascular malformation.     

Effects of T cell adoptive transfer into nude mice on alveolar bone resorption induced by endotoxin

Using the method of reconstitution of nude mice with T cells, we examined the effects of T cell on alveolar bone resorption induced by repeated injections of Escherichia coli endotoxin into periodontal tissue. Three mice groups (normal, nude and T cell reconstituted nude mice) were used. Endotoxin derived from E. coli was repeatedly injected into the gingiva of the mice left mandibles every 48 h and the mice were killed on the day after the 1st, 4th, 7th, 10th, 13th and 20th injections of endotoxin. Alveolar bone resorption was examined histopathologically and histomorphometrically. Bone surfaces in contact with the osteoclast were defined as the site of active resorption and the ratios of active resorption were compared among the 3 nice groups. Consequently, no active resorption was found after the first injection of endotoxin in any group. After the 4th injection, active resorption was found in normal nice and T cell reconstituted nude mice and gradually rose with the increase in the injection frequency. In contrast, few osteoclasts were found even after the 10th injection in the nude mice. In addition, there were statistically significant differences between the normal price and nude mice after the 4th and 10th injections (p<0.05). These findings suggested that T cell influences periodontal bone destruction induced by local administration of endotoxin during the early phases.     

Basic and clinical evaluation of the measurement of bone resonant frequency

Summary A new computerized apparatus was constructed to measure the resonant frequency of human ulnain vivo with high sensitivity and reproducibility. Experimental studies using aluminum bar and dried human bone revealed the importance of the ulna being positioned parallel to the radius, approximately 90 degree flexion of the elbow joint, and minimal muscle activity in order to demonstrate maximum resonant frequency of ulna. Measurement of bone resonance in monkeysin vivo and after removal of the bonein vitro showed good agreement. Product of F (maximum resonant frequency in Hz) and L (ulnar length in cm), FL, indicating the speed of propagation of sound wave through the ulna, showed a significant positive correlation with bone mineral content/bone width (BM/BW) measured by Norland-Cameron apparatus and age-bound decline in both sexes. Patients with osteomalacia and primary hyperparathyroid bone disease tended to have higher FL values than expected from BM/BW. Two-dimensional display of FL and BM/BW thus appears to be useful in distinguishing osteoporosis from osteomalacia better than the use of BM/BW alone.     

Eye Movements during Perception of Pictures in Chronic Schizophrenia

Using a device of our own built eye movements during the perception of some pictures were examined in 24 chronic schizophrenic and 20 normal subjects. While they were shown each of 4 pictures for 30 seconds, we plotted the points on which the subject's eyes fixed for a short time and observed their traces. We also recorded EOG during the eye closure for 17 cases of these schizophrenic subjects. Additional observations and comparison of eye movements during the perception with EOG findings led to the following conclusions: 1. Concerning the degree of diffusion of the eye's fixation points, the moving range of the gaze in chronic schizophrenics was much more limited than in normal subjects. 2. There was observed rather large number appearance of the small rapid eye movements with closed eyes in the schizophrenic subjects who showed limited moving range of eye's fixation points. Chronic schizophrenic patients probably look at a certain part vaguely. This may be due to their decreased motivation and lack of interest in trying to get information about the pictures and to cognize them.     

Leiomyoma of the left posterior tibial artery: A case report

A case of leiomyoma of the left posterior tibial artery is presented. This tumor produced aneurysmal dilatation of the artery and was treated successfully by surgery. This may be the first documented case of a benign smooth muscle tumor, although nearly 100 leiomyosarcomas arising from large arteries and veins have been described in the literature.