医院感染流行病学监测分析

介绍了我院１９９３年７月１日～１９９３年１２月２０日出院的１０３１例病人医院感染病率的监测分析，半年中感染率为８．４％，妇产科疗区发病率高于外科疗区，感染部位以泌尿道、下呼吸道、手术伤口为最多，侵袭性操作及易感因素引起的感染在感染病例中分别占４０．２％和５９．８％。     

~(60)Co-γ射线照射后HeLa细胞存活曲线和数学模式

本文研究了~(60)Co-γ射线照射后HeLa细胞的存活曲线,比较了两种数学模式拟合的结果.拟合优度以对误差加权的残差平方和(Q)作为统计指标进行评价.结果表明模式的拟合度较模式为优.     

用纤支镜为支气管哮喘患者作肺灌洗的安全性观察

本文对12例支气管哮喘病人作了22例次支气管肺泡灌洗,其中3例次为重度哮喘发作;8例次为中度发作[1];11例次为缓解期.灌洗方法在一般肺灌洗的基础上经过改良后,12例病人无1例死亡.11例次哮喘发作患者,灌洗后临床症状皆有不同程度改善.11例次缓解期病人,灌洗后皆无不良反应.凡哮喘时间较长者,均能灌洗出较大量脓痰栓.     

胆汁4种初级结合型胆汁酸的多因素判别对胆汁成石性的判断价值

本文运用二值回归判别法探讨了胆汁中4种初级结合型胆汁酸含量变化对胆汁成石性的判断价值。根据52例测试数据得出4因素二类判别函数:Y=0.0395X_1-0.0386X_2 0.0185X_3 O.0586X_4-1.0513。87例自、回代结果表明,该判别函数在判断符合率、错误率、假阳性率、假阴性率等诸方面均较使用1种初级结合型胆汁酸作为判别指标优越。     

An investigation on changes in blood CuZn-superoxide dismutase contents in type I, II schizophrenics]

Blood CuZn superoxide dismutase (CuZn-SOD) changes during neuroleptic drugs treatment were measured by means of double-antibody immunoradiometric assay, in 121 schizophrenics (77 cases with Type I and 44 cases with Type II), and 128 normal subjects as control group. The results revealed: (1) before treatment, the overall blood content of CuZn-SOD in patient group showed higher significantly than that of control group (t = 12.34, P less than 0.001); (2) the content of CuZn-SOD in Type I schizophrenics was higher than that of Type II (t = 13.93, P less than 0.001); (3) after treatment, the CuZn-SOD content decreased obviously in Type I (t = 7.715, P less than 0.001), while no significant change in Type II was encountered (t = 0.541, P less than 0.05). The pathophysiological mechanisms of dopamine-Oxygen free radicals relating to the Type I and Type II schizophrenics was discussed briefly.     

Inhibition of tumor promotion in benzo[a]pyrene-initiated CD-1 mouse skin by crocetin

The effects of topical application of crocetin on 12-O-tetradecanoylphorbol-13-acetate(TPA)-induced promotion of skin tumors, hyperplasia, hydrogenperoxide, ornithine decarboxylase (ODC) and inflammation wereevaluated in female CD-1 mice. Topical application of crocetin(0.2 or 1.0 µmol) with TPA (15 nmol) twice weekly for20 weeks to mice previously initiated with benzo[     

Investigation of the nonlinear aspects of imaging through a highly scattering medium.

The edge-spread function that is expected when imaging a sharp edge in a highly scattering medium using a time-of-flight imaging system has been investigated. Experimental results have been compared with computer simulations. The effect of scattering is to broaden the image of the edge, accompanied by an offset of the midpoint (50% transmission) of the edge. Small random errors in the measurement of the time of flight results in an increase in the offset of the edge position at very short times of flight. The offset in the midpoint of the edge is evidence of the nonlinear nature imaging process, in view of which we conclude that nonlinear algorithms will be necessary to maximize the image information available from measured intensities.     

国产氟康唑对小鼠隐球菌病的疗效

以５×１０３ｃｆｕ／鼠的新型隐球菌给小鼠脑室感染（ｉｃ）１ｈ后，分别口服氟康唑（Ｆｌｕ）５和１０ｍｇ／（ｋｇ·ｄ）或酮康唑（Ｋｅｔ）５０和１００ｍｇ／（ｋｇ·ｄ），ｂｉｄ×９ｄ。对ｉｃ小鼠连续观察４０天的存活率和平均存活时间，Ｆｕｌ分别为５０％～７０％和８～１５天，Ｋｅｔ是３０％～４０％和５～９天。由小鼠侧尾静脉注射１０６ｃｆｕ／鼠新型隐球菌３天后产生的全身感染，分别给小鼠口服Ｆｌｕ２．５～１０ｍｇ／（ｋｇ·ｄ）或Ｋｅｔ２５～１００ｍｇ／（ｋｇ·ｄ），ｂｉｄ×９ｄ。感染２４、２８和３２天的ＰＤ５０Ｆｌｕ是２．７、３．５和６．７ｍｇ／ｋｇ，Ｋｅｔ为２８．４、７０．４和８３ｍｇ／ｋｇ；Ｆｌｕ和Ｋｅｔ的平均存活时间分别是２３～３４天和２０～３１天。在上述两种实验模型中分离脑和肺做细菌培养，Ｆｌｕ均与对照和５０ｍｇ／（ｋｇ·ｄ）的Ｋｅｔ比较，对ｉｃ１０天及静脉注射感染１３天的小鼠，口服５和１０ｍｇ／（ｋｇ·ｄ）或２．５～１０ｍｇ／（ｋｇ·ｄ）Ｆｌｕ均显著抑制新型隐球菌生长。     

桡骨颈骨折经皮撬拨复位的远期疗效

用经皮撬拨复位治疗桡骨颈骨折56例,其中复位良好46例,较好6例和不良4例;经3年7个月平均随访,复位良好和较好的44例中,后期疗效良好32例,较好11例和一般1例。骨折解剖复位、撬拨复位的手术损伤轻和石膏固定时间较短是后期疗效满意的关键。成人桡骨颈骨折伴肘内侧副韧带严重损伤比儿童多见,但儿童桡骨颈骨折严重倾斜移位和完全移位比成人多见,后期疗效更满意。