Beiträge zur Histologie der hyperplastischen Rachentonsille mit besonderer Berücksichtigung der Tuberculose und Indication für die operative Entfernung

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Besprechungen

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Ohreiterung und Hirntuberkel

Ohne ZusammenfassungDer dasselbe Thema behandelnde Aufsatz von Haike (A. f. O., Bd. 58, S. 206) konnte bei der Abfassung dieser Arbeit nicht mehr berücksichtigt werden, da dieselbe bereits zum Druck gegeben war, als jener Band des Archivs erschien. Verf.     

Oral dye therapy in urogenital infections

From our seven years' experience with the azo dyes, we have found them of definite value in combating urogenital infections. These drugs, especially pyridium (to which we confined the major part of our study), have proved superior to the older urinary antiseptics in common use. They are practically harmless in their action (apart from the anorexia and nausea occasionally observed), have a wider field of usefulness by acting equally well in alkaline or acid urine, are synergistic to most other remedies and require no special dietary regime. Their analgesic effect upon the inflamed mucosa of the urogenital tract is considerable. They are mild deodorants. In renal and prostatic infections the results are better than in cystitis and urethritis, but even in the latter affections they are of greater value than internal antiseptics hitherto used. Some strains of Escherichia coli are retarded as effectively as staphylococci. We believe that the azo dyes merit further clinical study before they are assigned to oblivion. Investigations to determine the possible selectivity of certain dyes for special bacterial groups open vistas of untold possibilities.Notwithstanding the great practical value of combined clinical and laboratory research, we believe there will remain much in the empirical inheritance of the dyes which will not be fully explicable by present-day investigation. Their actions and reactions within the test-tube and the utilization of their properties in therapy will not always parallel. This means that in certain uses of dyes, the value of which is attested by clinical experience, certain phenomena cannot be fully explained by laboratory tests now known. Nevertheless, such clinical observations often prove a very substantial contribution to therapeutics.     

STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : II. THE CHEMICAL DEGRADATION OF THE SPECIFIC ANTIGEN OF TYPE Z SHIGELLA PARADYSENTERIAE (FLEXNER)

The chemical and enzymatic dissociation of the specific antigen of Type Z Shigella paradysenteriae has been studied. The chemical, toxic, and serological properties of the products of degradation have been investigated. The nature of the toxic component has been discussed.