全文获取类型
收费全文 | 199852篇 |
免费 | 2876篇 |
国内免费 | 97篇 |
专业分类
耳鼻咽喉 | 1401篇 |
儿科学 | 7156篇 |
妇产科学 | 3313篇 |
基础医学 | 19912篇 |
口腔科学 | 2000篇 |
临床医学 | 15325篇 |
内科学 | 36394篇 |
皮肤病学 | 1137篇 |
神经病学 | 18797篇 |
特种医学 | 9651篇 |
外国民族医学 | 3篇 |
外科学 | 32278篇 |
综合类 | 2556篇 |
现状与发展 | 1篇 |
一般理论 | 10篇 |
预防医学 | 19805篇 |
眼科学 | 3134篇 |
药学 | 11061篇 |
中国医学 | 693篇 |
肿瘤学 | 18198篇 |
出版年
2023年 | 152篇 |
2022年 | 340篇 |
2021年 | 614篇 |
2020年 | 427篇 |
2019年 | 664篇 |
2018年 | 22572篇 |
2017年 | 17831篇 |
2016年 | 20003篇 |
2015年 | 1605篇 |
2014年 | 1683篇 |
2013年 | 1939篇 |
2012年 | 8793篇 |
2011年 | 22948篇 |
2010年 | 19701篇 |
2009年 | 12406篇 |
2008年 | 20973篇 |
2007年 | 23156篇 |
2006年 | 1992篇 |
2005年 | 3617篇 |
2004年 | 4651篇 |
2003年 | 5485篇 |
2002年 | 3672篇 |
2001年 | 630篇 |
2000年 | 736篇 |
1999年 | 508篇 |
1998年 | 454篇 |
1997年 | 418篇 |
1996年 | 238篇 |
1995年 | 254篇 |
1994年 | 218篇 |
1993年 | 176篇 |
1992年 | 257篇 |
1991年 | 305篇 |
1990年 | 327篇 |
1989年 | 254篇 |
1988年 | 230篇 |
1987年 | 200篇 |
1986年 | 190篇 |
1985年 | 191篇 |
1984年 | 161篇 |
1983年 | 137篇 |
1982年 | 132篇 |
1981年 | 105篇 |
1980年 | 129篇 |
1979年 | 97篇 |
1978年 | 92篇 |
1977年 | 75篇 |
1976年 | 61篇 |
1974年 | 82篇 |
1938年 | 65篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Debra L. Roter Richard M. Frankel Judith A. Hall David Sluyter 《Journal of general internal medicine》2006,21(1):28-34
Relationship-centered care reflects both knowing and feeling: the knowledge that physician and patient bring from their respective domains of expertise, and the physician’s and patient’s experience, expression, and perception of emotions during the medical encounter. These processes are conveyed and reciprocated in the care process through verbal and nonverbal communication. We suggest that the emotional context of care is especially related to nonverbal communication and that emotion-related communication skills, including sending and receiving nonverbal messages and emotional self-awareness, are critical elements of high-quality care. Although nonverbal behavior has received far less study than other care processes, the current review argues that it holds significance for the therapeutic relationship and influences important outcomes including satisfaction, adherence, and clinical outcomes of care. 相似文献
12.
杨娅 Thomas Bartel Loredana Latina Guido Caspari 王新房 Raimund Erbel 《华中科技大学学报(医学英德文版)》2002,22(2):158-163
Coronary flow reserve (CFR) has been used toassess coronary microcirculation and epicardial coro-nary stenoses[1— 3 ] . CFR is defined as the ratio ofcoronary flow under maximal coronary vasodilatationto coronary flow under resting conditions[4 ] .Whenthe cross- sectional area of epicardial coronary arteriesis constant,coronary flow velocity (CFV) ratios areequal to volume flow ratios.The most common method used clinically formeasuring CFVR is intracoronary Doppler flow(ICD) analysis re… 相似文献
13.
14.
R G Jones J W Bass M E Weisse J M Vincent 《The Pediatric infectious disease journal》1991,10(8):557-559
We tested the urine of 30 infants 6 weeks to 7 months of age after they received standard 10-micrograms (0.5-ml) doses of HbOC (HibTITER) Haemophilus influenzae b (Hib) conjugate vaccine for the presence of Hib antigenuria using a commercially available latex particle agglutination assay (Directigen). Urines were collected within 1 hour, from 1 to 3 hours, at 24 hours and at 3, 6 and 9 days after vaccine administration and reactions were quantitated from 0 to 3+. In contrast to previous studies in older children which showed little or no antigenuria following HbOC vaccination, our study shows that in infants intense Hib antigenuria is evident within 2 to 3 hours and persists 3 days after vaccine administration and that less intense antigenuria may be detected in some infants for several days. With efficacious vaccines now being used in 2- to 6-month-old infants, invasive Hib disease may soon be limited to infants of this age just before their seroconversion. It should be recognized that antigenuria occurs for several days after vaccination with Hib conjugate vaccines and that it could be erroneously interpreted as evidence of invasive Hib infection. 相似文献
15.
16.
17.
18.
19.
5-Amino-4-imidazolecarboxamide (AICA) riboside, the nucleoside corresponding to AICA ribotide (AICAR or ZMP), an intermediate of the de novo pathway of purine biosynthesis, was found to exert a dose-dependent inhibition on gluconeogenesis in isolated rat hepatocytes. Production of glucose from lactate-pyruvate mixtures was half-maximally inhibited by approximately 100 microM and completely suppressed by 500 microM AICA riboside. AICA riboside also inhibited the production of glucose from all other gluconeogenic precursors investigated, i.e., fructose, dihydroxyacetone, and L-proline. Measurements of intermediates of the glycolytic-gluconeogenic pathway showed that AICA riboside provoked elevations of triose phosphates and fructose-1,6-bisphosphate and decreases in fructose-6-phosphate and glucose-6-phosphate. The effects of AICA riboside persisted when the cells were washed 10 min after its addition but were suppressed by 5-iodotubercidin, an inhibitor of adenosine kinase. AICA riboside provoked a dose-dependent buildup of normally undetectable Z nucleotides. After 20 min of incubation with 500 microM AICA riboside, ZMP, ZTP, and ZDP reached 3, 0.3, and 0.1 mumol/g cells, respectively. Concentrations of ATP were not significantly modified by addition of up to 500 microM AICA riboside when the cells were incubated with lactate-pyruvate but decreased with fructose or dihydroxyacetone. The activity of rat liver fructose-1,6-bisphosphatase was inhibited by ZMP with an apparent Ki of 370 microM. It is concluded that AICA riboside exerts a suppressive effect on gluconeogenesis because it provokes an accumulation of ZMP, which inhibits fructose-1,6-bisphosphatase.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
20.
Paul Hochstein Ulrich Glatzel Thomas Schmickal Andreas Wentzensen 《Trauma und Berufskrankheit》2002,4(2):s110-s114
The treatment of deep cartilage defects in load-bearing joints is a problem that still has no satisfactory solution. Full-thickness defects of the articular cartilage rarely heal spontaneously, usually leaving damage that can lead to early arthrosis. Techniques currently available for the treatment of chondral defects include abrasion, drilling, micro-fracturing, transplantation of tissue autografts and allografts, and cell transplantation. Osteochondral autograft transplantation is currently the only surgical cartilage repair technique known to lead to the formation of genuine hyaline articular cartilage and its retention at least in the medium term. The Draenert method, in which a water-cooled diamond bone-cutting system is used, is an effective procedure for resurfacing the joints affected by localised cartilaginous defects, even when there is also severe bone loss. Donor-side morbidity can be kept to a minimum by filling the defect caused by harvesting with a press-fit cylinder of cancellous bone covered with periosteum for protection. 相似文献