全文获取类型
收费全文 | 325095篇 |
免费 | 40283篇 |
国内免费 | 1465篇 |
专业分类
耳鼻咽喉 | 5353篇 |
儿科学 | 9700篇 |
妇产科学 | 6971篇 |
基础医学 | 35647篇 |
口腔科学 | 10236篇 |
临床医学 | 43576篇 |
内科学 | 74804篇 |
皮肤病学 | 9289篇 |
神经病学 | 32197篇 |
特种医学 | 10470篇 |
外国民族医学 | 101篇 |
外科学 | 46028篇 |
综合类 | 1093篇 |
现状与发展 | 40篇 |
一般理论 | 66篇 |
预防医学 | 34191篇 |
眼科学 | 6631篇 |
药学 | 17322篇 |
中国医学 | 708篇 |
肿瘤学 | 22420篇 |
出版年
2023年 | 6083篇 |
2022年 | 1879篇 |
2021年 | 5985篇 |
2020年 | 7090篇 |
2019年 | 5754篇 |
2018年 | 13939篇 |
2017年 | 11856篇 |
2016年 | 12379篇 |
2015年 | 13049篇 |
2014年 | 15691篇 |
2013年 | 20800篇 |
2012年 | 19316篇 |
2011年 | 19064篇 |
2010年 | 14432篇 |
2009年 | 14742篇 |
2008年 | 16861篇 |
2007年 | 16820篇 |
2006年 | 16799篇 |
2005年 | 15276篇 |
2004年 | 13848篇 |
2003年 | 12444篇 |
2002年 | 11759篇 |
2001年 | 7916篇 |
2000年 | 7330篇 |
1999年 | 7201篇 |
1998年 | 2959篇 |
1997年 | 2641篇 |
1996年 | 2642篇 |
1995年 | 2312篇 |
1994年 | 1639篇 |
1993年 | 1403篇 |
1992年 | 3941篇 |
1991年 | 3509篇 |
1990年 | 3242篇 |
1989年 | 3008篇 |
1988年 | 2864篇 |
1987年 | 2564篇 |
1986年 | 2440篇 |
1985年 | 2178篇 |
1984年 | 1643篇 |
1983年 | 1486篇 |
1979年 | 1266篇 |
1978年 | 967篇 |
1977年 | 911篇 |
1974年 | 1057篇 |
1973年 | 1051篇 |
1972年 | 1008篇 |
1971年 | 966篇 |
1970年 | 922篇 |
1969年 | 928篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
71.
A mixed‐method study of effects of a therapeutic play intervention for children on parental anxiety and parents' perceptions of the intervention
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)
72.
73.
74.
75.
Haya Mohammed BSc MChB M. Yousuf Salmasi MRCS Massimo Caputo PhD Gianni D. Angelini PhD Hunaid A. Vohra PhD 《Journal of cardiac surgery》2020,35(6):1209-1219
Background
Limited data exists demonstrating the efficacy of minimally invasive surgery (MIS) compared to median sternotomy (MS) for multiple valvular disease (MVD). This systematic review and meta-analysis aims to compare operative and peri-operative outcomes of MIS vs MS in MVD.Methods
PubMed, Ovid, and Embase were searched from inception until August 2019 for randomized and observational studies comparing MIS and MS in patients with MVD. Clinical outcomes of intra- and postoperative times, reoperation for bleeding and surgical site infection were evaluated.Results
Five observational studies comparing 340 MIS vs 414 MS patients were eligible for qualitative and quantitative review. The quality of evidence assessed using the Newcastle-Ottawa scale was good for all included studies. Meta-analysis demonstrated increased cardiopulmonary bypass time for MIS patients (weighted mean difference [WMD], 0.487; 95% confidence interval [CI], 0.365-0.608; P < .0001). Similarly, aortic cross-clamp time was longer in patients undergoing MIS (WMD, 0.632; 95% CI, 0.509-0.755; P < .0001). No differences were found in operative mortality, reoperation for bleeding, surgical site infection, or hospital stay.Conclusions
MIS for MVD have similar short-term outcomes compared to MS. This adds value to the use of minimally invasive methods for multivalvular surgery, despite conferring longer operative times. However, the paucity in literature and learning curve associated with MIS warrants further evidence, ideally randomized control trials, to support these findings.76.
Rosario Gulias-Cañizo Anell Lagunes-Guillén Arturo González-Robles Erika Sánchez-Guzmán Federico Castro-Muñozledo 《Burns : journal of the International Society for Burn Injuries》2019,45(2):398-412
Background
Since recent reports have shown that (-)-Epigallocatechin-3-gallate (EGCG) could be used for treating proliferative and inflammatory disorders, we explored its use for the management of corneal chemical burns.Materials and methods
Initially, EGCG was assayed on the rabbit corneal epithelial cell line RCE1(5T5) to establish the best testing conditions, and to avoid unwanted outcomes in the experimental animals. Then, we studied its effects on cell proliferation, cell cycle progression and cell differentiation. Afterwards, we instilled EGCG in experimental grade II corneal alkali burns in mice, three times a day up to 21 days, and evaluated by slit lamp examination and histological sections of corneal epithelial, corneal endothelial and stromal edema, as well as the presence of inflammatory cells and neovascularization.Results
EGCG reduced cell growth and led to a decline in the proportion of proliferative cells in a concentration dependent manner. At 10 μM, EGCG promoted cell differentiation, an effect not related with apoptosis or cytotoxicity. When 10 μM EGCG was instilled in corneal alkali burns in mice three times a day up to 21 days, EGCG significantly reduced corneal opacity and neovascularization. The improved clinical appearance of the cornea was associated to a controlled epithelial growth; epithelial morphology was similar to that observed in normal epithelium and contrasted with the hyperproliferative, desquamating epithelium observed in control burn wounds. EGCG reduced corneal, stromal and endothelial edema, and wound inflammation.Conclusion
This work constitutes the first evidence for the use of EGCG in the acute phase of a corneal alkali burn, representing a possible novel alternative to improve patient outcomes as an add-on therapy. 相似文献77.
78.
79.
80.
Factors predicting the development of pressure ulcers in an at‐risk population who receive standardized preventive care: secondary analyses of a multicentre randomised controlled trial
下载免费PDF全文
![点击此处可从《Journal of advanced nursing》网站下载免费的PDF全文](/ch/ext_images/free.gif)