全文获取类型
收费全文 | 291篇 |
免费 | 5篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 2篇 |
妇产科学 | 4篇 |
基础医学 | 13篇 |
口腔科学 | 7篇 |
临床医学 | 20篇 |
内科学 | 49篇 |
皮肤病学 | 38篇 |
神经病学 | 12篇 |
特种医学 | 26篇 |
外科学 | 31篇 |
综合类 | 44篇 |
预防医学 | 30篇 |
眼科学 | 7篇 |
药学 | 8篇 |
中国医学 | 6篇 |
肿瘤学 | 9篇 |
出版年
2018年 | 2篇 |
2014年 | 2篇 |
2013年 | 3篇 |
2012年 | 4篇 |
2011年 | 19篇 |
2010年 | 11篇 |
2009年 | 8篇 |
2008年 | 9篇 |
2007年 | 12篇 |
2006年 | 15篇 |
2005年 | 14篇 |
2004年 | 15篇 |
2003年 | 17篇 |
2002年 | 11篇 |
2001年 | 12篇 |
2000年 | 7篇 |
1999年 | 5篇 |
1998年 | 9篇 |
1997年 | 6篇 |
1996年 | 15篇 |
1995年 | 9篇 |
1994年 | 4篇 |
1993年 | 14篇 |
1992年 | 7篇 |
1991年 | 10篇 |
1990年 | 8篇 |
1989年 | 6篇 |
1988年 | 7篇 |
1987年 | 5篇 |
1986年 | 3篇 |
1985年 | 2篇 |
1984年 | 4篇 |
1983年 | 4篇 |
1982年 | 5篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1970年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1963年 | 1篇 |
1960年 | 2篇 |
1958年 | 1篇 |
1957年 | 2篇 |
1956年 | 1篇 |
1948年 | 1篇 |
排序方式: 共有307条查询结果,搜索用时 15 毫秒
91.
As part of its ongoing mission to inform and support trustees and staff of health foundations and corporate giving programs, Grantmakers In Health (GIH), in conjunction with the Health and Environmental Funders Network (HEFN), held a day-long Issue Dialogue on two important environmental health issues: antibiotic resistance and systemic contaminants. Experts and advocates from many organizations came together to discuss concerns and opportunities, as well as current and potential roles for health philanthropy. This Issue Brief brings together key points from the day's discussion with factual information on environmental health drawn from a background paper prepared for the participants. 相似文献
92.
K. M. Kilbride F. L. Paveglio A. L. AltstattRID=""ID="" <E>Present address:</E> Chiswell Lane Silver Spring MD USA W. G. Henry C. A. JanikRID=""ID="" <E>Present address:</E> Palo Verde Albuquerque NM USA 《Archives of environmental contamination and toxicology》1998,35(2):236-248
Throughout the western United States, studies have identified various detrimental effects of contaminants to aquatic biota
from the use of agricultural drainage water for management of arid wetlands. However, little is known about the relative contributions
of contaminant loading from pollutants dissolved in water compared with those carried by drifting material (e.g., detritus) associated with drainage water. Consequently, we determined loading rates for contaminants dissolved in water and
those incorporated by drifting material for drainage (Diagonal Drain) as well as fresh (S-Line Canal) water used for wetland
management at Stillwater National Wildlife Refuge (SNWR), Nevada during the early, middle, and late periods of the irrigation
season (June through mid-November) in 1993. We found loading rates for trace elements throughout the irrigation season were
almost entirely (> 98%) associated with contaminants dissolved in the water rather than incorporated by drift. Although drift
contributed little to the total loading for trace elements to SNWR wetlands, contaminant concentrations were much greater
in drift compared with those dissolved in water. Loading rates for dissolved As, B, Hg, and total dissolved solids (TDS) differed
among periods for the Diagonal Drain. Along the Diagonal Drain, loading rates for dissolved As, B, Hg, Mo, unionized ammonia
(NH3-N), TDS, and Zn differed among its three sampling sites. B was the only trace element with differences in loading rates for
drift among periods from the Diagonal Drain. In contrast, loading rates for As, B, Cr, Cu, Hg, Se, and Zn in drift differed
among periods for the S-Line Canal. Along Diagonal Drain, loading rates in drift for B (middle and late periods), Cr, Cu,
and Zn differed among sites. Hg (xˉ ≥ 12.0 ng/L) and NH3-N (xˉ ≥ 0.985 mg/L) dissolved in water as well as B (xˉ ≥ 97.4 μg/g DW) and Hg (xˉ ≥ 0.461 μg/g DW) in drift from the Diagonal
Drain and S-Line Canal exceeded screening levels (SLs) for protection of aquatic biota throughout the irrigation season. Dissolved
As (xˉ ≥ 0.0426 mg/L) in water from the Diagonal Drain during all periods exceeded the SL for protection of aquatic biota.
Dissolved B (xˉ = 1.03 mg/L) in water from the Diagonal Drain during the early period exceeded the SL for protection of aquatic
biota.
Received: 18 September 1997/Accepted: 5 February 1998 相似文献
93.
花生四烯酸氧化产物对肾毒性肾炎肾脏血液动力学的影响 总被引:4,自引:1,他引:4
应用血栓素合成抑制剂、5-脂氧化酶抑制剂及12-脂氧化酶抑制剂对肾毒性肾炎大鼠进行预处理,测定其肾小球滤过率、肾血流量及肾小球合成的前列腺素E2、血栓素B2、白三烯B4及12-羟二十碳四烯酸。发现这三种抑制剂分别抑制制肾小球合成血栓素B2、白三烯B4及12-羟二十碳四烯酸,并缓解了肾小球滤过率及肾血流量的下降程度。由此证实以上三种物质参与肾毒性肾炎中的肾脏血液动力学紊乱。 相似文献
94.
Michael N. Koss MD Liselotte Hochholzer MD Peter W. Nichols MD LTC William D. Wehunt MC USA LCDR Angeline A. Lazarus MC USNR 《Human pathology》1983,14(12):1024-1038
The authors studied 161 cases of primary non-Hodgkin's lymphomas and pseudolymphomas of lung. Small lymphocytic proliferations, which they believe to be lymphomas, constituted 31.6 per cent of cases; plasmacytoid lymphocytic and small cleaved follicular center cell lymphomas (Lukes-Collins system), 22.4 and 11.8 per cent of cases, respectively; and the remaining follicular center cell lymphomas and B-immunoblastic sarcomas, 5.6 per cent of cases. Pseudolymphomas constituted 14 per cent of cases. Most patients were elderly and asymptomatic; in most cases a solitary nodule or infiltrate was observed on a chest radiograph. Radiographic evidence of effusion was found in both lymphomas and pseudolymphomas, but hilar adenopathy was restricted to lymphomas. A few peribronchial reactive germinal centers and intralesional giant cells/granulomas were seen frequently in unequivocal lymphomas, so their presence cannot be used to exclude neoplasia. A generally monomorphic cell population and invasion of bronchial cartilage or visceral pleura are suggestive of malignancy, whereas primitive cytologic appearance and invasion of lymph nodes or parietal pleura are pathognomonic of malignancy. Diffusely admixed mature lymphocytes and plasma cells with numerous reactive follicles suggest pseudolymphomas. Immunologic determination of clonality may be diagnostically definitive. Most localized lesions in lung were treated by surgical resection, whereas in cases of extensive pulmonary disease, biopsies were performed and patients were treated by chemotherapy or irradiation. Both lymphomas and pseudolymphomas recurred, most often within three years. Pseudolymphoma recurred only in lung. When distant spread of lymphoma occurred, it commonly involved extranodal sites. Only 18 of 101 patients with lymphoma died with or of tumor, and no patient with pseudolymphoma died of disease. Neither histologic subtype among the "small cell" lymphoid lymphomas nor the presence of regional node involvement was prognostically significant, but pleural effusion on the initial chest radiograph was a significant predictor of both recurrence and mortality. 相似文献
95.
近视药物治疗研究进展 总被引:26,自引:0,他引:26
本研究复习本世纪以来 (2 0 0 0年~ 2 0 0 4年 )有关近视药物治疗问题的文献。方法是主要通过PubMed ,对“myopia”进行检索 ,同时也参考一些重要会议最新资料。 相似文献
96.
Stromal Progenitor Cells Present Within Liposuction and Reduction Abdominoplasty Fat for Autologous Transfer to Aged Skin 总被引:1,自引:0,他引:1
Mitchell Stashower MC USN Kathleen Smith MC USA John Williams MC USN Henry Skelton MD 《Dermatologic surgery》1999,25(12):945-949
BACKGROUND: Autologous fat is used for direct transfer to locally replace fat, as well as for use intradermally in the treatment of rhytids in aged skin. OBJECTIVE: To determine if the components of the autologous fat could be separated to produce a better agent for the treatment of rhytids. METHODS: Liposuction material from four patients and fat from abdominoplasty from five patients was processed by homogenization and centrifugation to separate mature lipocytes from other stromal cell populations in its associated extracellular matrix, and then to separate this from the blood and cellular debris. The cellular layer was evaluated histologically and with the immunohistochemical antibodies for CD34, SM-actin, S-100 protein, MIB-1, Bcl-2, and factor XIIIa. RESULTS: The cellular layer showed spindle cells, some small vascular structures, a small amount of mature fat, and extracellular matrix. CD34 showed diffuse staining of most spindle and endothelial cells in all sections, factor XIIIa showed only focal staining of spindle and dendritic cells, and Bcl-2 showed light to moderate staining in scattered cells within the cellular component. S-100 protein, SM-actin, and MIB-1 were negative. CONCLUSION: Processed liposuction and abdominoplasty processed fat may be ideal for the treatment of wrinkles in aged skin because it contains progenitor stromal cells that are known to be present within the fat and which may be concentrated by processing methods. 相似文献
97.
98.
目的评价一种含0.3%Triclosan和1.1%sodium monofluorophosphate(SMFP)新型牙膏抑制牙菌斑和唾液中变异链球菌数的效果。方法对239名12-13岁学生进行为期6个月的临床检查,在首次及以后的第3个月和第6个月进行。检查内容包括牙菌斑计数和唾液中变异链球菌数的检测。结果(1)与对照组相比较,实验组3个月和6个月后的牙菌斑计数有很明显的降低,两组间有显著性差异(P分别为0.016和0.047)。(2)两组唾液中变异链球菌数在6月后均有明显降低,但无显著性差异(P=0.41)。结论含0.3%triclosan和1.1%SMFP新型牙膏能显著抑制牙菌斑的形成。 相似文献
99.
MAJ Norvell V. Coots M.D. USAR LTC Dirk M. Elston M.D. USA 《Pediatric dermatology》1997,14(6):466-469
Abstract: We present an infant born with bilaterally symmetric, anterior and posterior port-wine stains. These leslons presented a striking resemblance to Rorschach inkblots, a phenomenon not previously reported. A discussion of the case as well as a discussion of syndromes associated with port-wine stains is provided. 相似文献
100.
Abstract: Tinea capitis is unusual in postpubertal individuals and is frequently misdiagnosed. In cases of inflammatory disease, prompt initiation of therapy is essential to prevent scarring and permanent hair loss. Two examples are presented to illustrate principles of evaluation and treatment. 相似文献