全文获取类型
收费全文 | 3913篇 |
免费 | 345篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 44篇 |
儿科学 | 105篇 |
妇产科学 | 25篇 |
基础医学 | 541篇 |
口腔科学 | 45篇 |
临床医学 | 411篇 |
内科学 | 776篇 |
皮肤病学 | 55篇 |
神经病学 | 283篇 |
特种医学 | 367篇 |
外科学 | 609篇 |
综合类 | 64篇 |
一般理论 | 1篇 |
预防医学 | 265篇 |
眼科学 | 97篇 |
药学 | 228篇 |
中国医学 | 2篇 |
肿瘤学 | 362篇 |
出版年
2023年 | 18篇 |
2022年 | 43篇 |
2021年 | 139篇 |
2020年 | 74篇 |
2019年 | 105篇 |
2018年 | 136篇 |
2017年 | 82篇 |
2016年 | 102篇 |
2015年 | 95篇 |
2014年 | 126篇 |
2013年 | 157篇 |
2012年 | 268篇 |
2011年 | 281篇 |
2010年 | 148篇 |
2009年 | 125篇 |
2008年 | 198篇 |
2007年 | 192篇 |
2006年 | 184篇 |
2005年 | 163篇 |
2004年 | 135篇 |
2003年 | 133篇 |
2002年 | 115篇 |
2001年 | 74篇 |
2000年 | 66篇 |
1999年 | 49篇 |
1998年 | 64篇 |
1997年 | 65篇 |
1996年 | 53篇 |
1995年 | 36篇 |
1994年 | 53篇 |
1993年 | 31篇 |
1992年 | 45篇 |
1991年 | 59篇 |
1990年 | 63篇 |
1989年 | 79篇 |
1988年 | 56篇 |
1987年 | 44篇 |
1986年 | 50篇 |
1985年 | 33篇 |
1984年 | 27篇 |
1983年 | 24篇 |
1982年 | 29篇 |
1981年 | 29篇 |
1980年 | 20篇 |
1979年 | 17篇 |
1978年 | 21篇 |
1977年 | 25篇 |
1975年 | 18篇 |
1974年 | 15篇 |
1973年 | 17篇 |
排序方式: 共有4280条查询结果,搜索用时 15 毫秒
51.
Charlotte V. Hobbs Jan Drobeniuc Theresa Kittle John Williams Paul Byers Panayampalli S. Satheshkumar Kengo Inagaki Meagan Stephenson Sara S. Kim Manish M. Patel Brendan Flannery CDC COVID- Response Team CDC COVID- Response Team Bailey Alston Shanna J. Bolcen Darbi Boulay Peter Browning Li Cronin Ebenezer David Tonya Hayden Han Li Travis Lim Panagiotis Maniatis Palak Patel Mathew Pauly Amanda Poe Lili Punkova Vera Semenova Evelene P. Steward-Clark Alexandra Tejada Briana Zellner 《MMWR. Morbidity and mortality weekly report》2021,70(9):312
52.
RAJVIR BHALWAR HS SANDHU RC AHUJA GK SINGH RP MISRA 《Medical Journal Armed Forces India》1994,50(3):175-180
A population based hybrid design combining element of cohort and cross-sectional approach was used to develop a simple clinical algorithm to predict individual probability of developing hypertension (systolic BP > 140 mm Hg and/or diastolic BP > 90 mmHg). 3615 soldiers initially normotensive at the time of induction into high altitude, were studied by systematic random sampling. Multiple logistic regression analysis showed a high significant association between hypertension and age, body mass index (BMI), tobacco smoking and alcohol consumption. Using the constant/coefficient values obtained from the logistic model and the receiver operating characteristics (ROC) curve analysis, the following predictive rule was developed – To the age in years, add (BMIx 3.86); also add 5.53 if he is a smoker; and add 19.81 if he consumes alcohol. If the total exceeds 142, the individual is at high risk of developing hypertension. This algorithm carries a sensitivity of 68.2% and specificity of 78.5%.KEY WORDS: Hypertension, High altitude 相似文献
53.
A 3 year old Turkish girl is described who was suffering from major histocompatibility complex (MHC) class II deficiency syndrome, which is characterised by the lack of expression of HLA class II antigens on mononuclear cells. The presence of HLA class II genes was demonstrable at the DNA level. Combined immunodeficiency was indicated by hypogammaglobulinaemia and the absence of delayed type hypersensitivity on skin testing. Further, she was unable to produce specific antibodies towards foreign antigens and suffered from recurrent pulmonary, gastrointestinal, and septic infections from the third month of life. The clinical course was complicated by a Coombs test positive haemolytic anaemia due to the production of autoantibodies against the rhesus "e' antigen, a non-glycosylated protein antigen. Haemolysis could be controlled by oral steroid treatment. This case is of interest as it shows that despite the absence of HLA class II antigens and combined immunodeficiency autoimmune reactions with production of specific autoantibodies directed to protein antigens are possible. 相似文献
54.
55.
McClellan M. Walther Edward D. Eanes Thomas F. Delaney William D. Travis 《Urology》1996,47(6):831-835
Objectives
We analyzed bladder calcifications occurring after photodynamic therapy administered for the treatment of superficial bladder cancer, a finding not previously reported after this treatment.Methods
Bladder biopsies from 20 patients undergoing photodynamic therapy were evaluated. Bladder calcifications were identified in 2 patients and analyzed for composition.Results
One patient had diffuse microcrystalline deposition in two biopsies composed of calcium oxalate monohydrate A. A second patient had a focal stone at a healing biopsy site composed of monoclinic calcium hydrogen phosphate dihydrate (brushite) (66%), calcium oxalate (25%), hydroxyapatite (6%), and protein (3%).Conclusions
Rare calcium oxalate and brushite calcifications were identified after photodynamic therapy and presumed to occur because of tissue injury associated with treatment. 相似文献56.
57.
58.
59.
Hansen KJ Cherr GS Craven TE Motew SJ Travis JA Wong JM Levy PJ Freedman BI Ligush J Dean RH 《Journal of vascular surgery》2000,32(3):472-81; discussion 481-2
PURPOSE: This retrospective review describes the surgical management of consecutive patients with severe hypertension and ischemic nephropathy due to atherosclerotic renovascular disease. METHODS: From January 1987 through December 1998, a total of 590 patients underwent operative renal artery repair at our center. A subgroup of 232 hypertensive patients (97 women, 135 men; mean age, 66 +/- 8 years) with atherosclerotic renovascular disease and preoperative serum creatinine levels of 1.8 mg/dL or more forms the basis of this report. Change in renal function was determined from glomerular filtration rates estimated from preoperative and postoperative serum creatinine. The influence of selected preoperative parameters and renal function response on time to dialysis and dialysis-free survival was determined by a proportional hazards regression model. RESULTS: In all, 83 patients underwent unilateral renal artery repair and 149 patients underwent bilateral repair, including repair to a solitary kidney in 17 cases. A total of 332 renal arteries were reconstructed, and 32 nephrectomies were performed in these patients. After surgery, there were 17 deaths (7.3%) in the hospital or within 30 days of surgery. Advanced patient age (P =.001; hazard ratio, 1.1; 95% CI [1.1, 1.2]) and congestive heart failure (P =.04; hazard ratio, 2.9 CI [1.0, 8.6]) demonstrated significant and independent associations with perioperative mortality. With a change of 20% or more in EGFR being considered significant, 58% of patients had improved renal function, including 27 patients removed from dialysis dependence; function was unchanged in 35% and worsened in 7%. Follow-up death from all causes or progression to dialysis dependence demonstrated a significant and independent association with early renal function response. Both patients whose function was unchanged (P =.005; hazard ratio, 6.0; CI [2.2, 16.6]) and patients whose function was worsened (P =.03; hazard ratio, 2.2; CI [1.1, 4. 5]) remained at increased risk of death or dialysis dependence. For patients with unchanged renal function after operation, risk of death or dialysis demonstrated a significant interaction with preoperative renal function. In addition to severe preoperative renal dysfunction, diabetes mellitus demonstrated a significant and independent association with follow-up death or dialysis. CONCLUSION: Surgical correction of atherosclerotic renovascular disease can retrieve excretory renal function in selected hypertensive patients with ischemic nephropathy. Patients with improved renal function had a significant and independent increase in dialysis-free survival in comparison with patients whose function was unchanged and patients whose function was worsened after operation. These results add further evidence in support of a prospective, randomized trial designed to define the value of renal artery intervention in patients with ischemic nephropathy. 相似文献
60.
A case of reflex sympathetic dystrophy is presented in a 12-year-old girl with comorbid conversion disorder. Her identical twin also had a conversion disorder. This is the first reported case of coexistence of reflex sympathetic dystrophy and conversion disorder. It is important for clinicians to be aware that these conditions may coexist since the presentation of symptoms differ, even though there are shared features of treatment. 相似文献