Contemporary Analysis of Sentinel Lymph Node Biopsy Performance Among Patients with Clinically Localized Merkel Cell Carcinoma

Annals of Surgical Oncology -     

火针对脑卒中偏瘫患者肢体功能的康复效果Meta 分析

目的:通过Meta分析评价火针对脑卒中痉挛性偏瘫患者肢体功能康复的影响。方法:计算机检索Cochrane Library、Medline、Web of Science、EMbase、Ovid、Pubmed、中国生物医学文献数据库、中国知网、维普数据库、万方数据库中火针对脑卒中痉挛性偏瘫患者肢体功能进行干预的随机对照试验(RCT)。试验组为火针疗法或在对照组的基础上进行火针治疗,对照组为常规的康复锻炼、常规针刺(体针、电针等)、常规治疗等。采用Revman5.3软件对2组Fugl-Meyer运动功能量表(FMA)评分、临床痉挛指数(CSI)、有效率进行Meta分析。结果:共纳入16篇文献,包括1 061例研究对象。Meta分析结果显示:与对照组比较,试验组CSI [Z=4.55,P0.05,MD=-0.82,95%CI=(-1.17,-0.47)]、FMA评分[Z=7.43,P0.05,MD=9.00,95%CI=(6.63,11.38)]、有效率[Z=6.35,P0.05,OR=3.37,95%CI=(2.32,4.91)]均较优。结论:火针能改善脑卒中痉挛性偏瘫患者的肢体功能,促进患者的康复。     

Diagnosis of sacroiliac joint pain: validity of individual provocation tests and composites of tests

Previous research indicates that physical examination cannot diagnose sacroiliac joint (SIJ) pathology. Earlier studies have not reported sensitivities and specificities of composites of provocation tests known to have acceptable inter-examiner reliability. This study examined the diagnostic power of pain provocation SIJ tests singly and in various combinations, in relation to an accepted criterion standard. In a blinded criterion-related validity design, 48 patients were examined by physiotherapists using pain provocation SIJ tests and received an injection of local anaesthetic into the SIJ. The tests were evaluated singly and in various combinations (composites) for diagnostic power. All patients with a positive response to diagnostic injection reported pain with at least one SIJ test. Sensitivity and specificity for three or more of six positive SIJ tests were 94% and 78%, respectively. Receiver operator characteristic curves and areas under the curve were constructed for various composites. The greatest area under the curve for any two of the best four tests was 0.842. In conclusion, composites of provocation SIJ tests are of value in clinical diagnosis of symptomatic SIJ. Three or more out of six tests or any two of four selected tests have the best predictive power in relation to results of intra-articular anaesthetic block injections. When all six provocation tests do not provoke familiar pain, the SIJ can be ruled out as a source of current LBP.