Clinical syndrome of potassium intoxication

Potassium intoxication in man results in widespread impairment of neuromuscular function. Potassium produces a characteristic sequence of electrocardiographic changes, impaired contraction of the heart recognizable by auscultation, and final arrest of the heart in diastole. Flaccid paralysis may also be present, involving the extremities and to a lesser degree the trunk but sparing the cranial nerves for the most part.Two cases with elevation of serum potassium manifesting this clinical syndrome are described. Following administration of sodium chloride, both paralysis and electrocardiographic changes reverted toward normal.The genesis of potassium intoxication, the typical sequence of electrocardiographic changes, the nature of the paralysis and the therapeutic approach are discussed.     

An assessment of the construct validity of the CHU9D in the Australian adolescent general population

Purpose  

To assess the construct validity of the CHU9D in an adolescent general population sample. The CHU9D is a new generic preference-based measure of health-related quality of life developed specifically for application in the economic evaluation of health care treatments and interventions for young people.