全文获取类型
收费全文 | 9759篇 |
免费 | 499篇 |
国内免费 | 86篇 |
专业分类
耳鼻咽喉 | 70篇 |
儿科学 | 237篇 |
妇产科学 | 312篇 |
基础医学 | 968篇 |
口腔科学 | 184篇 |
临床医学 | 829篇 |
内科学 | 2584篇 |
皮肤病学 | 166篇 |
神经病学 | 999篇 |
特种医学 | 473篇 |
外科学 | 1405篇 |
综合类 | 28篇 |
一般理论 | 3篇 |
预防医学 | 386篇 |
眼科学 | 138篇 |
药学 | 642篇 |
中国医学 | 19篇 |
肿瘤学 | 901篇 |
出版年
2023年 | 51篇 |
2022年 | 152篇 |
2021年 | 283篇 |
2020年 | 159篇 |
2019年 | 254篇 |
2018年 | 312篇 |
2017年 | 233篇 |
2016年 | 256篇 |
2015年 | 293篇 |
2014年 | 397篇 |
2013年 | 483篇 |
2012年 | 766篇 |
2011年 | 728篇 |
2010年 | 389篇 |
2009年 | 418篇 |
2008年 | 606篇 |
2007年 | 577篇 |
2006年 | 577篇 |
2005年 | 599篇 |
2004年 | 523篇 |
2003年 | 494篇 |
2002年 | 451篇 |
2001年 | 110篇 |
2000年 | 102篇 |
1999年 | 102篇 |
1998年 | 93篇 |
1997年 | 89篇 |
1996年 | 75篇 |
1995年 | 57篇 |
1994年 | 52篇 |
1993年 | 34篇 |
1992年 | 69篇 |
1991年 | 47篇 |
1990年 | 47篇 |
1989年 | 32篇 |
1988年 | 46篇 |
1987年 | 35篇 |
1986年 | 40篇 |
1985年 | 39篇 |
1984年 | 29篇 |
1983年 | 27篇 |
1982年 | 30篇 |
1981年 | 27篇 |
1980年 | 19篇 |
1979年 | 16篇 |
1978年 | 15篇 |
1977年 | 12篇 |
1975年 | 10篇 |
1972年 | 14篇 |
1968年 | 11篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
Salvatore Squarcione Maria G. Pompa Daniela D'Alessandro 《European journal of epidemiology》1999,15(7):685-687
In 1994, the Italian Ministry of Health implemented a National Surveillance System to obtain data on the incidence of bacterial meningitis and its causative agents, including Haemophilus influenzae type b (Hib). As a consequence, case reporting of Hib meningitis is increasing year by year; in 1996, there were 126 notifications, of which 73% were in children under 2 years of age. Although underreporting still exists, parallel prospective or retrospective epidemiological surveys conducted in some Italian Regions allowed for partial correction of the incidence of Hib meningitis (up to 18.5/100,000 population in 1994). 相似文献
102.
Elio Ricchi M.D. Salvatore Fundarò M.D. Andrea Spallanzani M.D. Alfonso Carriero M.D. Alberto Farinetti M.D. Francesco Ferrara M.D. Carlo Pezcoller M.D. 《Diseases of the colon and rectum》1996,39(3):353-357
PURPOSE: Loss of a certain amount of cutaneous tissue of the perineal region may be remedied by first intention with creation of cutaneous flaps, thus preventing second intention healing. METHODS: We present three emblematic cases in which the posterior perineal region was reconstructed by means of vertical subcutaneous pedicle flaps, subsequent to cutaneous tissue loss after surgery for extensive condilomas or neoplastic pathologies. RESULTS: Tissue loss was repaired by means of a V-Y type vertical subcutaneous pedicle flap, constructed laterally of the extirpation zone and advanced in a median direction. In all cases, no ischemia or infection of flaps occurred; sphincteral continence and long-term aesthetic results have proved to be satisfactory. CONCLUSIONS: Vertical pedicle subcutaneous flaps are well vascularized, extremely mobile, and easy to perform and have no serious postoperative complications. 相似文献
103.
Maria A. Annunziata Ph.D. Carlo Rossi M.D. Renato Talamini Sc.D. Salvatore Tumolo M.D. Silvio Monfardini M.D. 《Supportive care in cancer》1996,4(5):334-340
The aim of this study was to determine the influence of socio-demographic and professional factors on physicians' attitudes to the terminally ill. Between May 1992 and May 1993, a survey was conducted in the province of Pordenone (north-east, Italy) in order to analyse a number of specific issues, such as emotional involvement, the need for aggressive treatments and the communication of diagnosis and prognosis. After obtaining a list of board-certified physicians from the Medical Association office in Pordenone, a modification of the cancer questionnaire of Haley and Blanchard (QSPT) was mailed to 916 doctors. Of these, 605 (60%; 487 male, 118 female; mean age 41 ± 11 SD) returned the completed questionnaire. Within the group of responders, we identified three main subgroups, according to their type of activity: general practitioners (175, 29%), hospital doctors (235, 39%) and other doctors (195, 32%). In age, sex and activity, the only significant difference between responders and non-responders was age (mean age 41 and 43 years respeetively). Most of the responders (77%) stated that they were able to deal with the terminally ill patient and his/her needs; 44%, however, admitted that patients' anxiety is sometimes unbearable. For the vast majority of the doctors polled (91%), providing a comfortable environment for an incurable patient was more important than pursuing aggressive treatment, but only 44% were convinced of the uselessness of aggressive care. To the question on whether to disclose information about imminent death to allow patients to prepare spiritually, 37% answered No, 38% Yes, and 25% were uncertain. Almost all responders (95%), however, believed in the beneficial effect of hope on the terminally ill. Ourresults suggest that doctors' professional and, most of all, sociodemographic and cultural factors determine the relationship with the patient on both the emotional and the clinical decision-making levels. 相似文献
104.
Emanuele Nicolai Alberto Cuocolo Leonardo Pace Antonio Nappi Pasquale Sullo Stefania Cardei Luigi Argenziano Fiorenzo Squame Peter J. Ell Marco Salvatore 《Journal of nuclear cardiology》1996,3(1):9-17
Background
Exercise and dipyridamole 99mTc-labeled methoxy isobutyl isonitrile (MIBI) myocardial scintigraphy have been widely used for the diagnosis of coronary artery disease (CAD). However, only limited data on adenosine 99mTc-labeled MIBI cardiac imaging are currently available. This study was designed to assess the accuracy of quantitative adenosinerest 99mTc-labeled MIBI tomography in the diagnosis and localization of CAD.Methods and Results
Fifty-seven consecutive patients with suspected CAD who underwent coronary angiography and 22 normal volunteers were studied. All patients underwent 99mTc-labeled MIBI tomography after administration of adenosine (140 μg/kg intravenously for 6 minutes) and at rest. A total of 171 vascular coronary territories were analyzed quantitatively. All patients with CAD (≥50% luminal stenosis) (n=55) had abnormal 99mTc-labeled MIBI tomograms. The normalcy rate was 86% by quantitative analysis. Overall sensitivity, specificity, and diagnostic accuracy for detection of individual stenosed vessels were 84%, 87%, and 85%, respectively. In patients with one-vessel CAD (n=24), sensitivity and diagnostic accuracy in the detection of individual stenosed vessels were significantly (p<0.05) higher compared with patients with multivessel CAD (n=31). Moreover, 75% of patients with one-vessel disease showed a scintigraphic pattern characterized by the presence of perfusion defects in only one coronary artery territory, and 74% of patients with multivessel disease showed a scintigraphic pattern characterized by the presence of perfusion defects in two or more coronary artery territories. Sensitivity, specificity, and diagnostic accuracy for detecting individual diseased vessels were similar in patients without previous myocardial infarction (n=18) compared with those with previous myocardial infarction (n=39). In myocardial territories related to noninfarcted areas (n=124), sensitivity and specificity in the detection of stenosed vessels were 75% and 88%. In infarcted areas (n=47), sensitivity and specificity in the detection of stenosed vessels were 98% and 80% (differences not significant vs noninfarcted areas).Conclusions
Adenosine-controlled coronary vasodilation combined with quantitative 99mTc-labeled MIBI tomography is accurate for identifying patients with CAD and localizing individual stenosed coronary arteries. 相似文献105.
Pasquale Sullo Alberto Cuocolo Emanuele Nicolai Stefania Cardei Antonio Nappi Fiorenzo Squame Eugenio M. Covelli Leonardo Pace Marco Salvatore 《European journal of nuclear medicine and molecular imaging》1996,23(6):648-655
The aim of this study was to evaluate the accuracy of quantitative 1-day exercise-rest technetium-99m tetrofosmin tomography in the identification of patients with coronary artery disease (CAD) and in the detection of individual stenosed coronary vessels. Sixty-one patients with suspected CAD who underwent coronary angiography and 13 normal volunteers were studied. All patients were submitted to two i.v. injections of99mTc-tetrofosmin, one at peak exercise (370 MBq) and the other (1110 MBq) at rest 3 h after exercise (images 15–30 min after injection for both studies). All patients with CAD (0% luminal stenosis) (n=50) had an abnormal99mTc-tetrofosmin tomogram. Only one patient without significant coronary narrowing showed abnormal findings. Overall sensitivity, specificity and diagnostic accuracy in the detection of individual stenosed vessels were 77%, 93% and 85%, respectively. Sensitivity and diagnostic accuracy in the identification of individuals stenosed coronary vessels were significantly higher (P<0.05) in patients with single-vessel disease (n=21) than in those with multivessel disease (n=29). Sensitivity, specificity and accuracy for detecting individual diseased vessels were similar in patients without previous myocardial infarction (n=26) and in those with previous myocardial infarction (n=35). In myocardial territories related to non-infarcted areas (n=128), sensitivity and specificity in the detection of stenosed vessels were 70% and 95%, respectively. In infarcted areas (n=55), sensitivity and specificity in the detection of stenosed vessels were 85% (P=NS vs non-infarcted areas) and 75% (P<0.05 vs non-infarcted areas), respectively. Finally, sensitivity was significantly lower (P<0.05) in vascular territories supplied by vessels with moderate stenosis (50%–75%) than in those supplied by vessels with severe stenosis (>75%). The results of this study demonstrate that quantitative 1-day exercise-rest99mTc-tetrofosmin single-photon emission tomographic imaging is a suitable and accurate technique to identify patients with CAD and to detect individual stenosed coronary vessels. 相似文献
106.
107.
108.
Progetto ATENA,A study on the etiology of major chronic diseases in women: Design,rationale and objectives 总被引:2,自引:0,他引:2
S. Panico R. Dello Iacovo E. Celentano R. Galasso P. Muti M. Salvatore M. Mancini 《European journal of epidemiology》1992,8(4):601-608
In spite of their important impact on populations, a number of diseases - all types of cancer and coronary heart disease in women - are rare events for statistical analysis and often analyzed in designs affected by selection and information biases, such as case-control studies. Large cohort studies based on the storage of biological specimens appear to be the most suitable solution for identifying risks for those diseases.Progetto ATENA, a study on the etiology of major chronic diseases in women is based on this design. Ten thousand women, aged 30–69 years, living in the area of the city of Naples, free of cancer and cardiovascular disease, are being recruited over a four-year period. Ten per cent of the cohort is being randomly selected from the electoral roles, the rest will be volunteers.Information on dietary habits, reproductive history, familiarity for chronic disease, active smoking habits and passive smoking exposure, physical activity, and socio-demographic data are being collected. Clinical data such as blood pressure, anthropometry, and electrocardiogram are also taken. All the participants provide biological samples of blood (fasting drawing) and urine (timed morning spot). The biological samples are processed in order to explore the main areas under study (nutritional markers, metabolism, endocrinology, genetics, environmental exposure markers, thrombogenesis). The samples are stored in liquid nitrogen (–196° C) as soon as the blood and urine processing have been finished. An appropriate follow-up information system on the health status of the participants is being set up to estimate incidence and mortality rates.Corresponding author. 相似文献
109.
To study residential treatment outcome, a follow-up questionnaire sent to families of former child patients was used to assign them to categories of "good", "fair," or "poor" overall adjustment. The three groups were compared on variables such as presenting symptoms, duration of psychotherapy, amount of drug therapy, and prognosis on discharge; several therapist variables were also studied. Findings, some unexpected, are discussed. 相似文献
110.
Pacilli P Viganò P Cogno M Aliprandi PL Brioschi S Cruciani S Guarneri A 《Il Giornale di chirurgia》2000,21(10):375-378
Thymoma, the most common tumor mediastinum, is a neoplasm arising from the epithelial cells of thymus. Nearly all thymomas present in adult life. Thymomas in children are exceptional. Chest X-ray, CT, magnetic resonance and fine-needle aspiration help for diagnosis. Surgical resection represents the treatment of choice and the outcome of surgery has been shown to depend on the local invasiveness of the tumor. 相似文献