全文获取类型
收费全文 | 5626篇 |
免费 | 331篇 |
国内免费 | 32篇 |
专业分类
耳鼻咽喉 | 97篇 |
儿科学 | 138篇 |
妇产科学 | 90篇 |
基础医学 | 587篇 |
口腔科学 | 179篇 |
临床医学 | 526篇 |
内科学 | 1190篇 |
皮肤病学 | 73篇 |
神经病学 | 318篇 |
特种医学 | 233篇 |
外科学 | 982篇 |
综合类 | 138篇 |
一般理论 | 1篇 |
预防医学 | 359篇 |
眼科学 | 161篇 |
药学 | 616篇 |
中国医学 | 63篇 |
肿瘤学 | 238篇 |
出版年
2023年 | 77篇 |
2022年 | 156篇 |
2021年 | 280篇 |
2020年 | 172篇 |
2019年 | 198篇 |
2018年 | 251篇 |
2017年 | 146篇 |
2016年 | 168篇 |
2015年 | 154篇 |
2014年 | 222篇 |
2013年 | 298篇 |
2012年 | 420篇 |
2011年 | 430篇 |
2010年 | 212篇 |
2009年 | 171篇 |
2008年 | 307篇 |
2007年 | 313篇 |
2006年 | 267篇 |
2005年 | 217篇 |
2004年 | 202篇 |
2003年 | 188篇 |
2002年 | 148篇 |
2001年 | 88篇 |
2000年 | 89篇 |
1999年 | 89篇 |
1998年 | 36篇 |
1997年 | 32篇 |
1996年 | 19篇 |
1995年 | 29篇 |
1994年 | 23篇 |
1993年 | 21篇 |
1992年 | 54篇 |
1991年 | 47篇 |
1990年 | 43篇 |
1989年 | 50篇 |
1988年 | 52篇 |
1987年 | 40篇 |
1986年 | 31篇 |
1985年 | 28篇 |
1984年 | 28篇 |
1983年 | 24篇 |
1982年 | 11篇 |
1981年 | 15篇 |
1980年 | 12篇 |
1979年 | 25篇 |
1978年 | 12篇 |
1977年 | 11篇 |
1976年 | 15篇 |
1974年 | 16篇 |
1973年 | 10篇 |
排序方式: 共有5989条查询结果,搜索用时 15 毫秒
91.
Saeed Khan Nadeem N Jaffer Mohammad Nasherwan Khan Mohammad A Rai Majid Shafiq Adnan Ali Shahid Pervez Nusrat Khan Aliya Aziz Syed H Ali 《International journal of infectious diseases》2007,11(4):313-317
INTRODUCTION: Human papillomavirus (HPV) is recognized as a major causative agent for cervical carcinomas. Based on their oncogenic potential, HPV subtypes have been divided into high- and low-risk. In Pakistan, screening for HPV in female patients is not commonly practiced, and as a consequence, the degree of HPV prevalence and its correlation with cervical cancer is unknown. OBJECTIVE: In this study, we have attempted to estimate the prevalence of HPV infection, and also the HPV subtype profile, among Pakistani women with cervical cancer from varied geographical, racial, and social backgrounds within Pakistan. METHODOLOGY: Women visiting two tertiary care hospitals in Karachi, diagnosed with carcinoma of the cervix within the past 15 years, were analyzed for HPV subtypes in their cancer specimens. Retrospectively, 60 paraffin-embedded cervical cancer biopsies were examined for the presence of HPV DNA. After DNA extraction from these samples, polymerase chain reaction (PCR) was used to amplify the HPV L1 gene using the consensus (general) primers, and primers specific for subtypes 16 and 18. RESULTS: Of the 60 samples analyzed, only one sample was HPV negative; the rest of the samples were positive for the presence of HPV. Of the 59 HPV positive samples, 56 showed the presence of HPV16 and one sample was positive for HPV18; HPV subtype could not be determined in two samples. CONCLUSION: Our results show a strong relationship between HPV infection and cervical cancer among Pakistani women. These results underscore the need to implement regular HPV screening for Pakistani women. An early diagnosis of HPV infection will allow better health management to reduce the risk of developing cervical cancer. 相似文献
92.
Extended follow‐up of pediatric liver transplantation patients receiving once daily calcineurin inhibitor
下载免费PDF全文
![点击此处可从《Pediatric transplantation》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Henry C. Lin Hector Melin‐Aldana Saeed Mohammad Udeme D. Ekong Estella M. Alonso 《Pediatric transplantation》2015,19(7):709-715
We describe longitudinal results in a cohort of pediatric liver transplant patients successfully minimized to once daily CNI monotherapy for longer than five yr and assess changes in liver biochemistries and liver histology. A retrospective chart review of all pediatric liver transplant patients at a single center was performed. Biopsies and serum biochemistries (AST, ALT, total bilirubin, direct bilirubin, INR, creatinine) are reported at time points: PM, five‐yr, seven‐yr, and nine‐yr post‐minimization. Biopsies were assessed for inflammation and fibrosis using Ishak and Batts grading systems. Successful minimization to daily CNI monotherapy was defined as normal liver enzymes with no episodes of rejection. Thirty‐three patients have successfully remained on once daily CNI for >5 yr, and 19/33 of these patients have serial liver biopsies available for review. We report on the clinical and histological findings of these 19 patients. All 19 patients continue to have normal liver biochemistries. On post‐minimization biopsies, fibrosis progressed by ≥2 stages in one patient (5.3%) despite normal liver biochemistries. Carefully selected patients can tolerate minimization to once daily CNI monotherapy as few have progression of fibrosis. 相似文献
93.
94.
The electrophysiology of antidromic reentry, a less common phenomenon than orthodromic reentry, remains a poorly understood aspect of the Wolff-Parkinson-White (WPW) syndrome. We used a pacing model of ventricular preexcitation in patients without WPW, so that electrophysiological events in the normal pathway during atrial extrastimulation (A1-A2 technique) could be precisely delineated without the obscuring effect of an actual accessory pathway. Ventricular preexcitation was simulated by an A1-V1 sequential basic drive with A2-V2 extrastimulation at progressively shorter A1-A2 (equal to V1-V2) coupling intervals. At each coupling interval tested within the zone of atrioventricular (A-V) nodal effective refractory period (since anterograde block of A2 was considered mandatory for manifestation of antidromic reentry), responses were assessed after A2 alone (method I), V2 alone (method II), and A2 plus V2 (method III, the complete preexcitation model). The entire pacing protocol was performed at two A-V intervals, short (50 msec) and long (150-180 msec), thereby simulating different proximities between the A pacing site and "accessory pathway" location. Of 47 consecutive unmedicated patients screened for the study protocol, 38 failed to meet minimal prerequisites for possible initiation of antidromic reentry because of failure in 18 (38% of total) to achieve anterograde A-V nodal block of A2, even though 1:1 ventriculoatrial conduction to cycle lengths less than or equal to 500 msec (less than or equal to 400 msec in 12) was present; and poor or absent ventriculoatrial conduction in the others. The nine remaining candidates underwent the full pacing protocol. Antidromic reentry (retrograde atrial response following V2 in method III) was observed in only two cases (4% of total), and both were associated with retrograde His-Purkinje system delays (documented by method II) occurring in tandem with a long A-V interval, thereby allowing for completion of retrograde A-V nodal recovery after penetration by A2. Indeed, such a prolonged recovery time prevented initiation of antidromic reentry in six of the nine patients (proven by intact ventriculoatrial conduction in method II). Retrograde A-V nodal block of V2, independent of A2, prevented an antidromic echo in one case. Findings in our model help to clarify the various factors, including specific anterograde and retrograde A-V nodal properties; anatomic relation between the accessory and normal pathways; and the retrograde His-Purkinje system delays, that must prevail in a concerted fashion to permit the initiation of antidromic reentry during the A1-A2 technique in patients with the WPW syndrome. 相似文献
95.
Saeed Mikaili Khosro Khademi-Kalantari Asghar Rezasoltani Parisa Arzani Alireza Akbarzadeh Baghban 《Journal of bodywork and movement therapies》2018,22(4):904-908
Objective
Due to the significant prevalence of knee disorders and patellofemoral pain syndrome, as well as the importance of quadriceps strengthening in knee rehabilitation programs, it is necessary to specify the best method to activate and strengthen the quadriceps muscles. The current study aimed at comparing the maximum generated isometric force during an active straight-leg-raising (SLR) maneuver in a sitting position by changing the hip rotational position with and without the simultaneous contraction of the ankle dorsiflexor muscles.Methodology
The current study was performed on 30 healthy males recruited with a non-random and available sampling method. The maximum generated force was measured during the SLR maneuver in six compound internal and external rotations and in a neutral position with and without ankle dorsiflexor contraction. The obtained generated force was analyzed using repeated measures ANOVA.Results
The generated forces in the SLR with and without contracting the ankle dorsiflexors were significantly different (p = 0.001), and taking different positions of hip rotation led to significant changes in the generated force (p = 0.005).Conclusion
The adoption of external hip rotation with the contraction of ankle dorsiflexors during the SLR maneuver generated the most force. Based on the interaction of these conditions, the general recommendation is to perform the SLR exercise in an external hip rotation with the simultaneous contraction of the ankle dorsiflexors in subjects with quadriceps muscle weakness. 相似文献96.
97.
Syed Ali Arsalan Naqvi Nasreen Badruddin Munsif Ali Jatoi Aamir Saeed Malik Wan Hazabbah Baharudin Abdullah 《Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine》2015,38(4):721-729
98.
Identification of novel CYP1B1 gene mutations in patients with primary congenital and primary open‐angle glaucoma
下载免费PDF全文
![点击此处可从《Clinical & experimental ophthalmology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
99.
100.
In-hospital care of end-stage renal disease (ESRD) patients, on hemodialysis, is different from the general population in various aspects. Non-nephrologists do not typically receive specialized training to take care of these patients. However, in most circumstances, they serve as the primary attending for these patients in the hospital setting. There is paucity of the literature guiding non-nephrologists on this important issue. This article highlights the key management aspects of in-hospital care of these patients that all the non-nephrologists should know. 相似文献