全文获取类型
收费全文 | 25710篇 |
免费 | 1798篇 |
国内免费 | 169篇 |
专业分类
耳鼻咽喉 | 204篇 |
儿科学 | 575篇 |
妇产科学 | 472篇 |
基础医学 | 3667篇 |
口腔科学 | 259篇 |
临床医学 | 2309篇 |
内科学 | 6057篇 |
皮肤病学 | 329篇 |
神经病学 | 2529篇 |
特种医学 | 862篇 |
外国民族医学 | 1篇 |
外科学 | 4772篇 |
综合类 | 161篇 |
一般理论 | 9篇 |
预防医学 | 1574篇 |
眼科学 | 286篇 |
药学 | 1546篇 |
中国医学 | 77篇 |
肿瘤学 | 1988篇 |
出版年
2023年 | 120篇 |
2022年 | 243篇 |
2021年 | 489篇 |
2020年 | 360篇 |
2019年 | 596篇 |
2018年 | 649篇 |
2017年 | 492篇 |
2016年 | 537篇 |
2015年 | 631篇 |
2014年 | 887篇 |
2013年 | 1209篇 |
2012年 | 1815篇 |
2011年 | 1960篇 |
2010年 | 1192篇 |
2009年 | 1123篇 |
2008年 | 1719篇 |
2007年 | 1765篇 |
2006年 | 1653篇 |
2005年 | 1730篇 |
2004年 | 1526篇 |
2003年 | 1550篇 |
2002年 | 1575篇 |
2001年 | 232篇 |
2000年 | 192篇 |
1999年 | 261篇 |
1998年 | 338篇 |
1997年 | 321篇 |
1996年 | 225篇 |
1995年 | 218篇 |
1994年 | 174篇 |
1993年 | 172篇 |
1992年 | 140篇 |
1991年 | 122篇 |
1990年 | 115篇 |
1989年 | 90篇 |
1988年 | 87篇 |
1987年 | 67篇 |
1986年 | 101篇 |
1985年 | 85篇 |
1984年 | 90篇 |
1983年 | 91篇 |
1982年 | 100篇 |
1981年 | 90篇 |
1980年 | 88篇 |
1979年 | 55篇 |
1978年 | 45篇 |
1977年 | 37篇 |
1976年 | 37篇 |
1975年 | 35篇 |
1974年 | 35篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
61.
62.
Claude Linassier Pascale Poumier-Gaschard Jean-Louis Bremond Carole Barin Oliver Haillot Jean Pierre Lamagnere Philippe Colombat 《Cancer chemotherapy and pharmacology》1992,30(3):233-234
Summary Simultaneous tumors are rarely encountered during the course of acute leukemias. We report on a case of seminoma of the testis that occurred during the evolution of acute myelogenous leukemia. To our knowledge, this stimultaneous association has not previously been described, but a causal relationship was not apparent in the present case. The likelihood of a common carcinogenesis existed, but direct exposure to carcinogens could not be established. Although the results of a physical examination and echography were normal at the time of diagnosis, we cannot exclude the presence of microscopic cancer of the testis. Since the dissemination pattern of seminoma is usually slower than that observed in this case and the disease remains limited to the lymph nodes for long periods following dissemination, the rapid development of the present case might have been attributable to the immunosuppression and the scrotal sepsis that occurred during the induction therapy. Immunosuppression might have stimulated the progression of a primary microscopic seminoma and the development of metastasis, whereas the scrotal sepsis and inflammation might have favored the occurrence of metastasis through bypass of the lymphatic barrier. 相似文献
63.
64.
Chemotherapeutics: antibiotics and other antimicrobials 总被引:3,自引:0,他引:3
65.
Robert G Kitchen Dale Mierau David Cassidy Pierre Dupuis 《The Journal of the Canadian Chiropractic Association》1988,32(1):11-15
Congenital dislocation of the hip (CDH) in an adult can accompany or cause mechanical low-back pain. This in turn, can create confusion in making the proper diagnosis. The mechanical alterations caused by CDH create an added strain to the lumbosacral spine. Manipulative treatment for back pain in these patients must not subject the dislocated hips to undue torque. 相似文献
66.
F. Pierre F. Baruthio F. Diebold P. Wild M. Goutet 《International archives of occupational and environmental health》1988,60(2):95-97
Summary During an epidemiological survey on arc welders, serum copper and ceruloplasmin were determined in two groups of workers. One group consisted of aluminum welders who were divided into two groups: 13 welders working inside aluminum tanks (confined atmosphere) and 8 welders engaged in the production of vans for dump trucks (nonconfined atmosphere). The reference group consisted of 26 workers of the same plant who were not exposed to welding fumes. Ozone, the major pollutant in aluminum arc welding, was thought to be the principal factor in the significant decrease (P < 0.01) of mean ceruloplasmin in confined welders. This decrease in the level of ceruloplasmin was still within the reference values and was not linked to age or to tobacco consumption. We found a linear relationship between ceruloplasmin concentration and the cumulated worktime along the week. This effect could be a sign in the serum of a lung reaction against oxidant activity in this type occupational exposure. 相似文献
67.
Alexander Kulik Marc Ruel Michael E Bourke Lynn Sawyer John Penning Howard J Nathan Thierry G Mesana Pierre Bédard 《European journal of cardio-thoracic surgery》2004,26(4):694-700
OBJECTIVE: Non-steroidal anti-inflammatory drugs (NSAIDs) are routinely used after coronary artery bypass surgery (CABG), yet their effects have seldom been evaluated in randomized controlled settings. The aim of this study was to examine the efficacy and safety of a commonly used NSAID, naproxen. We hypothesized that naproxen would reduce postoperative pain following CABG without increasing complications. METHODS: Patients (N=98) undergoing primary CABG were randomized to receive naproxen (500 mg q12hX5 doses via suppository started 1h after operation, followed by oral 250 mg q8hX6 doses) or placebo. Standard analgesic and anti-emetic regimens were available to both patient groups. Interventions were double-blinded. Primary end-points were postoperative pain measured before and after chest physiotherapy by visual analog scale and pulmonary slow vital capacity (SVC). RESULTS: Baseline characteristics were equivalent between the two groups. Over the first 4 postoperative days, naproxen decreased pain by 47+/-17% on average before chest physiotherapy (P=0.034), and 44+/-13% after chest physiotherapy (P=0.0092). Patients who received naproxen also had better preservation of SVC over the first 4 postoperative days (mean loss of SVC from baseline: 2.1+/-0.1 vs. 2.5+/-0.1l, naproxen vs. placebo, P=0.0032). This was concomitant with a lower white blood cell count observed in naproxen patients (9.2+/-0.3 vs. 12.7+/-1.5x10(9)/l, naproxen vs. placebo, P=0.03). Patients who received naproxen had more chest tube drainage after 4h postoperatively, but there was no difference in the incidence or amount of transfusions. There was no difference in medication use, length of stay, or in the incidence of atrial fibrillation, azotemia, and other complications. CONCLUSIONS: Naproxen is an effective and low-cost adjunct for optimization of pain control and lung recovery after CABG. Its use may result in increased chest tube drainage, but no apparent increase in other complications. 相似文献
68.
69.
70.
Alexandre Castro-Caldas Paul Delwaide Wolfgang Jost Marcelo Merello Adrian Williams Paolo Lamberti Miguel Aguilar Susanna Del Signore Pierre Cesaro 《Movement disorders》2006,21(4):500-509
Dopamine agonists have been recommended as early treatment for Parkinson's disease (PD), alone or combined with levodopa. Piribedil is a non-ergot selective D(2)/D(3) agonist with alpha(2) antagonist properties shown to be effective in the treatment of PD. This 12-month international, randomized, double-blind trial aimed to assess the efficacy of piribedil 150 mg versus bromocriptine 25 mg, in early combination with levodopa in Stage I to III PD patients. Motor efficacy was assessed using the Unified Parkinson's Disease Rating Scale (UPDRS III, Items 18-31) as improvement from baseline. Response rate was defined as a 30% improvement. Among the 425 randomly assigned patients, 178 were also included in a substudy on cognitive follow-up evaluated by a dysexecutive syndrome oriented battery. A relevant improvement in UPDRS III over the 12-month study duration was observed both in the piribedil and bromocriptine groups (-7.9 +/- 9.7 points from baseline versus -8.0 +/- 9.5; not significant [n.s.]) with a response rate of 58.4% and 55.3% (n.s.), respectively. Piribedil and bromocriptine resulted in similar improvement on all UPDRS III subscores. Piribedil patients required less levodopa dose increase than those on bromocriptine. Cognitive performance remained generally unchanged in both groups, with a significant effect of piribedil limited to the Wisconsin Card Sorting Test. An overall good tolerability of piribedil was observed. Early combination of piribedil 150 mg with levodopa resulted in significant long-term improvement of all motor symptoms in PD patients insufficiently controlled by levodopa alone. Taking into account both efficacy and acceptability in the long-term, piribedil proved in this bromocriptine controlled study to be an effective and safe treatment for PD. 相似文献