Use of sodium hypochlorite in therapy for acute intoxications with methemoglobin formers

The study of these intoxications has demonstrated that the blood level of methemoglobin (MH) is in conformity with the severity of intoxication. The pathospecific therapeutic effect of sodium hypochlorite (SHC) in acute intoxications of varying severity has been found to appear as a significant intensification of demethemoglobinization and as a three-fold reduction in the half-life of MH. The nonspecific effect of SHC manifests itself in correcting metabolic acidosis and in improving blood oxygenation. The use of SHC accelerates the regression of clinical manifestations of disease and reduces the length of inpatient treatment.     

Effect of sodium hypochlorite on the biotransformation of toxicants in acute poisoning by psychotropic agents

In acute poisoning by amitriptyline, carbazepine, barbiturates, and ethanol, the effect of sodium hypochlorite on the metabolism of toxicants is manifested as a considerable reduction in their high blood concentrations through oxidative transformation to inactive water-soluble derivatives and as the enhanced urinary elimination of the latter. The rate of the above process depends on the used dose of sodium hypochlorite.     

Diverticulosis of the large intestine]

Under observation were 47 patients with colonic diverticula. The clinical classification of diverticulosis of the colon is suggested. The principal method of treatment in patients with uncomplicated forms of the diverticulosis should be conservative. In profuse hemorrhage and intestinal obstruction as well as in perforation of the diverticulum, that would not respond to conservative therapy, surgery is indicated.     

Method of recording contractions of isolated blood vessels with the aid of a photoresistor

An apparatus for recording the tone and contractions of isolated vessels of various animals is described. The principle of the method consists of recording changes in the volume of an isolated vessel filled with Ringer-Locke solution by means of a photoresistor.     

Speech perception learning in patients with cochlear implants

A model of speech apprehensibility of postlingual patients after cochlear implantation has been developed. The study of filtrated speech comprehension by persons with normal hearing has used speech material in three 50 Hz spectral bands. The central frequencies were selected by tonotopics of the basilar cochlear membrane. Characteristics of speech comprehension and apprehensibility by recipients of cochlear implants are demonstrated. The model reveals problems of acoustic comprehension facing the implanted patients and shows importance of learning and personality features of the implanted patients for early rehabilitation.     

Histogenesis and structural organization of the walls of rat venae cavae and pulmonary veins

Using light and electron microscopic methods, the histogenesis and structural organization of the walls of rat venae cavae and pulmonary veins were studied in prenatal and postnatal periods of development. The special attention was paid to the appearance of the striated myocytes in the walls of these vessels during the process of ontogenesis. The time of initial divergent development of myoblastic differon was established, the stages of differentiation of striated myoblasts and the peculiarities of intercellular junctions were characterized, as well as the innervation and vascularization of the walls of venae cavae and pulmonary veins.     

Environmental hygiene and comprehensive processing of copper sulphate ore

The modern comprehensive processing of copper-sulphate ores is based on using the fire, chemical and combined fire-and-hydrometallurgy processes. The existing schemes of comprehensive ore processing do not provide for a total utilization of the metallurgical cycles wastes due to the inherent technological and design shortcomings; besides, they are a source of environmental pollution. Contamination of the atmospheric air with discharge elements has unfavorable effects on the health condition of population; it worsens the natural body resistance and contributes (through the induction of chromosome aberrations) to a higher general morbidity and mortality due to malignant neoplasms. Health-improve measures are supported by modern achievements in the sphere of copper-sulphate ore processing technologies--they ensure the hygienic and ecological rational management and usage at all stages of the processing of raw materials and secondary products. Institutions of the territorial medical-and-ecological monitoring are the corner stones for ecological safety of persons residing in areas of comprehensive copper-and-sulphate ore processing.