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101.
102.
Amanda Rodrigues Amorim Adegboye Danilo Dias Santana Pedro Paulo Teixeira dos Santos Paula Guedes Cocate Camila Benaim Maria Beatriz Trindade de Castro Michael Maia Schlüssel Gilberto Kac Berit Lilienthal Heitmann 《Nutrients》2021,13(3)
In this 2 × 2 factorial, outcome-assessor blinded, feasibility randomised trial we explored the effect of a non-pharmaceutical multi-component intervention on periodontal health and metabolic and inflammatory profiles among pregnant women with periodontitis receiving prenatal care in a Brazilian public health centre. 69 pregnant women (gestational age ≤20 weeks, T0) were randomly allocated into four groups: (1) fortified sachet (vitamin D and calcium) and powdered milk plus periodontal therapy during pregnancy (early PT) (n = 17); (2) placebo sachet and powdered milk plus early PT (n = 15); (3) fortified sachet and powdered milk plus late PT (after delivery) (n = 19); (4) placebo sachet and powdered milk plus late PT (n = 18). Third trimester (T1) and 6–8 weeks postpartum (T2) exploratory outcomes included periodontal health (% sites with bleeding on probing (BOP)), glucose, insulin, C-Reactive Protein, serum calcium and vitamin D. The mean BOP was significantly reduced in the early PT groups, while BOP worsened in the late PT groups. No significant effect of fortification on BOP was observed. Changes in glucose levels and variation on birthweight did not differ among groups This feasibility trial provides preliminary evidence for estimating the minimum clinically important differences for selected maternal outcomes. A large-scale trial to evaluate the interventions’ clinical benefits and cost-effectiveness is warranted. 相似文献
103.
Paula Francekovi Lucía García-Torralba Eleni Sakoulogeorga Tea Vu
kovi Federico J. A. Perez-Cueto 《Nutrients》2021,13(4)
The meat production industry is one of the leading contributors of greenhouse gas emissions. Cultured meat presents itself as a potential eco- and animal-friendly meat substitute which has the potential to eradicate animal cruelty and reduce both the environmental footprint and the risk of zoonotic illnesses, while delivering a nutrient-dense product. The purpose of this study was to investigate how consumers perceive cultured meat and if the frequency of meat consumption is related to their intention of trying or purchasing cultured meat. Data were collected online in 2020 from Croatia, Greece, and Spain. Among the 2007 respondents, three segments were identified according to meat consumption and variety, plus an a priori identified group of “non-meat eaters”. Sixty percent perceived cultured meat as kind to animals, 57% as unnatural, 45% as healthy and environmentally-friendly, 21% as disgusting, and only 16% as tasty. Although 47% of the respondents had not heard of cultured meat before, 47% would taste it and 41% would purchase it for the same price as conventional meat. This indicates that consumers from Croatia, Greece and Spain might be likely to purchase cultured meat if sold at an affordable price. 相似文献
104.
María-Jos de Castro Paula Snchez-Pintos Nisreem Abdelaziz-Salem Rosaura Leis María L. Couce 《Nutrients》2021,13(6)
Children with inborn errors of intermediary metabolism (IEiM) must follow special diets that restrict their intake of essential nutrients and may compromise normal growth and development. We evaluated body composition, bone mineral density, physical activity, and food intake in IEiM patients undergoing dietary treatment. IEiM patients (n = 99) aged 5–19 years and healthy age- and sex-matched controls (n = 98) were recruited and underwent dual-energy X-ray absorptiometry to evaluate anthropometric characteristics and body composition. Data on food intake and physical activity were also collected using validated questionnaires. The height z-score was significantly lower in IEiM patients than controls (−0.28 vs. 0.15; p = 0.008), particularly in those with carbohydrate and amino acid metabolism disorders. Significant differences in adiposity were observed between patients and controls for the waist circumference z-score (−0.08 vs. −0.58; p = 0.005), but not the body mass index z-score (0.56 vs. 0.42; p = 0.279). IEiM patients had a significantly lower total bone mineral density (BMD) than controls (0.89 vs. 1.6; p = 0.001) and a higher risk of osteopenia (z-score < −2, 33.3% vs. 20.4%) and osteoporosis (z-score < −2.5, 7.1% vs. 0%), but none presented fractures. There was a significant positive correlation between natural protein intake and BMD. Our results indicate that patients with IEiM undergoing dietary treatment, especially those with amino acid and carbohydrate metabolism disorders, present alterations in body composition, including a reduced height, a tendency towards overweight and obesity, and a reduced BMD. 相似文献
105.
Habib Ndema Steyn Petrus S. Boydell Victoria Cordero Joanna Paula Nguyen My Huong Thwin Soe Soe Nai Dela Shamba Donat Kiarie James 《Health services & outcomes research methodology》2021,21(2):188-205
Health Services and Outcomes Research Methodology - An interrupted time series with a parallel control group (ITS-CG) design is a powerful quasi-experimental design commonly used to evaluate the... 相似文献
106.
Stehr Paula Weber Winja Rossmann Constanze 《Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz》2021,64(1):37-44
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz - Der Anteil älterer Personen in der Bevölkerung wächst stetig. Gleichzeitig steigen im Alter die Risiken für... 相似文献
107.
Kelly C. Young-Wolff Julia Wei Nicole Varnado Normelena Rios Mary Staunton Carey Watson 《Women's health issues》2021,31(2):100-106
BackgroundThis study examined whether adverse childhood experiences (ACEs) are associated with increased risk of having an unwanted or mistimed pregnancy.MethodsWomen in two medical centers within an integrated health system were screened for ACEs during standard prenatal care (N = 745). Multinomial multivariable logistic regression analyses examined the associations of ACEs (count and type) with pregnancy intentions, adjusting for covariates.ResultsOverall, 58.3% of pregnant women reported no ACEs, 19.1% reported one ACE, and 22.7% reported two or more ACEs; 76.2% reported wanting to get pregnant, 18.5% reported wanting to get pregnant but not at this time (i.e., mistimed pregnancy), and 5.2% reported not wanting to get pregnant at all (i.e., unwanted pregnancy). Having two or more (vs. 0) ACEs was associated with higher odds of an unwanted pregnancy (odds ratio, 2.60; 95% confidence interval, 1.19–5.68). Further, childhood loss of parent (odds ratio, 2.20; 95% confidence interval, 1.03–4.71) and neglect (odds ratio, 5.67; 95% confidence interval, 1.72–18.72) were each associated with higher odds of an unwanted pregnancy in separate analyses. ACEs count and type were not significantly associated with having a mistimed pregnancy.ConclusionsAmong women screened for ACEs during standard prenatal care, ACEs were associated with increased odds of having an unwanted pregnancy, but not a mistimed pregnancy. Additional research is needed to better understand the mechanisms through which ACEs and other individual, social, and contextual factors impact pregnancy intentions to better support women and provide appropriate resources to help prevent unintended pregnancies. 相似文献
108.
Tony Wawina-Bokalanga Bert Vanmechelen Valentine Lhermitte Joan Martí-Carreras Valentijn Vergote Fara Raymond Koundouno Joseph Akoi-Bor Ruth Thom Tom Tipton Kimberley Steeds Kita Balla Moussa Ablam Amento Lies Laenen Sophie Duraffour Martin Gabriel Paula Ruibal Yper Hall Mandy Kader-Kond Stephan Günther Guy Baele Cesar Muoz-Fontela Johan Van Weyenbergh Miles W. Carroll Piet Maes 《Emerging infectious diseases》2021,27(1):76
We investigated the genetic profiles of killer cell immunoglobulin-like receptors (KIRs) in Ebola virus–infected patients. We studied the relationship between KIR–human leukocyte antigen (HLA) combinations and the clinical outcomes of patients with Ebola virus disease (EVD). We genotyped KIRs and HLA class I alleles using DNA from uninfected controls, EVD survivors, and persons who died of EVD. The activating 2DS4–003 and inhibitory 2DL5 genes were significantly more common among persons who died of EVD; 2DL2 was more common among survivors. We used logistic regression analysis and Bayesian modeling to identify 2DL2, 2DL5, 2DS4–003, HLA-B-Bw4-Thr, and HLA-B-Bw4-Ile as probably having a significant relationship with disease outcome. Our findings highlight the importance of innate immune response against Ebola virus and show the association between KIRs and the clinical outcome of EVD. 相似文献
109.
Evangelista André Nobre dos Santos Flávia Franciele de Oliveira Martins Lorena Pacheco Gaiad Thais Peixoto Machado Alex Sander Dias Rocha-Vieira Etel Costa Karine Beatriz Santos Ana Paula Oliveira Murilo Xavier 《Lasers in medical science》2021,36(6):1201-1208
Lasers in Medical Science - The aim of the present study was to investigate the effects of photobiomodulation (PBM) therapy on the expression of heat shock protein 70 (HSP70) and tissue repair in... 相似文献
110.
Barroso Rosmeire Aparecida Navarro Ricardo Tim Carla Roberta de Paula Ramos Lucas de Oliveira Luciane Dias Araki Ângela Toshie Fernandes Karina Gonzales Camara Macedo Daniela Assis Lívia 《Lasers in medical science》2021,36(6):1235-1240
Lasers in Medical Science - Acne vulgaris is the most recurring skin condition in the world, causing great harm to the physical and psychological well-being of many patients. Antimicrobial... 相似文献