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91.
PC Ng TF Fok CH Lee KL Cheung CK Li KW So W Wong PMP Yuen 《Acta paediatrica (Oslo, Norway : 1992)》1998,87(11):1197-1199
Two cases of homozygous α-thalassaemia who received active treatment in accordance with parental wishes are reported. One infant survived and the other, although successfully weaned off mechanical respiratory support, unexpectedly developed portal vein thrombosis and died. Homozygous a-thalassaemia, a condition previously considered to be universally fatal, and an indication for therapeutic abortion, is now potentially curable with advances in diagnostic technology and treatment. However, active management of these cases raises serious ethical questions and has major financial implications on the health-care system. Invasive prenatal and intensive postnatal interventions should remain experimental and cannot be recommended as routine clinical practice until the questions of long-term neurodevelopmental outcome, and the morbidity and mortality associated with bone-marrow transplantation have been fully addressed. As a result of advances in information technology, more and more parents of affected foetuses are likely to request active treatment. 相似文献
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Major A. K. Mehta P. C. Chamyal 《Indian journal of otolaryngology and head and neck surgery》1995,47(1):54-55
The present study has confirmed that EACA may be tried topically upon mild to moderate patients of Epistaxis at random without
any possibility of any major complication. 相似文献
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96.
P. C. Chamyal Maj P. S. Sukthankar 《Indian journal of otolaryngology and head and neck surgery》1997,49(4):364-367
Three rare and interesting cases of complete branchial cleft fistulae including two cases with unusual presentation are reported. Total excision of the fistulae was carried out by step ladder technique in all the three cases resulting in their successful surgical management. Relevant available literature on the subject has been reviewed. 相似文献
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99.
Thyrotoxicosis in children: thirty years'experience 总被引:3,自引:0,他引:3
Optimal treatment for thyrotoxicosis remains controversial in adults, but more so in paediatric practice. We have conducted a retrospective review of the records of 76 paediatric patients seen between 1965 and 1995 to determine management practice and outcome of therapeutic interventions. Seventeen are currently on antithyroid drug (ATD) treatment, while four have had their care transferred. Of the remaining 55, 21 (38%) achieved long-term remission with ATD alone following a mean treatment duration of 3.3 y (range 0.5-7 y). Block-replacement (high dose of ATD with thyroxine replacement) was more convenient than the titration regimen (3.4+/-0.3 visits to hospital per year versus 6.1+/-0.4, p<0.001). Surgery (subtotal/total thyroidectomy) was carried out in 27 patients, of whom 24 subsequently became hypothyroid and were treated with thyroxine. I131 was used successfully in six patients, two following surgery. ATD should remain the first-line therapy; a block-replacement regimen is more convenient. Surgery in a specialized centre carries a low risk. Caution should still be exercised in the use of I131 in young children. 相似文献
100.