全文获取类型
收费全文 | 586篇 |
免费 | 11篇 |
国内免费 | 36篇 |
专业分类
儿科学 | 39篇 |
妇产科学 | 2篇 |
基础医学 | 58篇 |
口腔科学 | 8篇 |
临床医学 | 63篇 |
内科学 | 61篇 |
皮肤病学 | 8篇 |
神经病学 | 3篇 |
特种医学 | 195篇 |
外科学 | 56篇 |
综合类 | 19篇 |
预防医学 | 39篇 |
眼科学 | 11篇 |
药学 | 20篇 |
中国医学 | 1篇 |
肿瘤学 | 50篇 |
出版年
2022年 | 3篇 |
2020年 | 2篇 |
2018年 | 6篇 |
2017年 | 4篇 |
2016年 | 5篇 |
2015年 | 11篇 |
2014年 | 12篇 |
2013年 | 10篇 |
2012年 | 8篇 |
2011年 | 11篇 |
2010年 | 21篇 |
2009年 | 37篇 |
2008年 | 23篇 |
2007年 | 34篇 |
2006年 | 33篇 |
2005年 | 29篇 |
2004年 | 18篇 |
2003年 | 12篇 |
2002年 | 20篇 |
2001年 | 31篇 |
2000年 | 9篇 |
1999年 | 25篇 |
1998年 | 29篇 |
1997年 | 34篇 |
1996年 | 23篇 |
1995年 | 11篇 |
1994年 | 9篇 |
1993年 | 12篇 |
1992年 | 12篇 |
1991年 | 5篇 |
1990年 | 10篇 |
1989年 | 21篇 |
1988年 | 20篇 |
1987年 | 10篇 |
1986年 | 11篇 |
1985年 | 7篇 |
1984年 | 3篇 |
1983年 | 4篇 |
1982年 | 2篇 |
1981年 | 7篇 |
1979年 | 6篇 |
1978年 | 2篇 |
1977年 | 4篇 |
1975年 | 3篇 |
1972年 | 2篇 |
1931年 | 1篇 |
1929年 | 2篇 |
1927年 | 2篇 |
1926年 | 7篇 |
1925年 | 3篇 |
排序方式: 共有633条查询结果,搜索用时 0 毫秒
71.
SG Carbia A Hochman M Chaín I Dei-Cas C Lagodín A Devés A Woscoff 《Journal of the European Academy of Dermatology and Venereology》2002,16(4):401-404
Mycosis fungoides (MF) may present with atypical clinical manifestations. Usually it mimics various chronic dermatoses, with the appearance of ulcers during the tumour stage. Infrequently, cutaneous ulcers are the main or initial sign of lymphoma. We report the case of a man who presented multiple skin lesions that clinically appeared to be pyoderma gangrenosum (PG). However, histological and immunohistochemical examination revealed MF. This case illustrates that PG-like ulcers maybe atypical cutaneous manifestations of MF and exceptionally the presenting sign of this disease. 相似文献
72.
73.
SG Gelsenkirchen 《MedR Medizinrecht》2007,25(9):569-571
Abstrakt 1. Eine mit der Ausübung vertrags?rztlicher T?tigkeit unvereinbare Interessen- und Pflichtenkollision liegt vor bei einer
faktischen Wahrnehmung der T?tigkeit eines Krankenhausarztes durch einen zugelassenen Arzt.
2. Ein Konsiliararzt ist ein Arzt mit einer anderen Fachgebietsbezeichnung, der in einem konkreten Behandlungsfall w?hrend
eines station?ren Aufenthalts auf seinem Fachgebiet untersucht und Behandlungsvorschl?ge macht, weil die entsprechende Fachkompetenz
in dem Krankenhaus nicht vorhanden ist. (Leits?tze des Bearbeiters) 相似文献
74.
75.
The authors consider transient processes for modifying arterial impedance, peripheral and elastic resistances of the arterial system, as well as some major hemodynamic parameters early in muscular performance. The analysis was made by applying experimental findings from 74 athletes. The transient processes were derived by using the mathematical modelling techniques on a computer. The termination of transient processes of arterial impedance and its determinants was shown to be asynchronous. Whether the values of arterial impedance at rest and during exercises of unlimited power are comparatively invariant is also discussed in the paper. 相似文献
76.
Total triboluminescence, i.e. optic radiation induced as a result of mechanic activation of venous blood in a TPA-2 triboluminometer, was measured in patients with cancer of the gastric cardia and esophagus, and in healthy subjects. The parameter was assessed in control water samples, too. In the 252-649 nm range, five bands of emission were registered with peaks at 262, 280, 360, 422 and 649 nm subject to variation in certain segments of blood spectrum. Triboluminescence of the venous blood at 280 nm determines for the total triboluminescence registered in the entire spectrum. The triboluminescence of capillary blood at 302 and 418 nm calculated using K coefficient facilitates differentiating between inflammation and cancer. This express test takes less than 1 minute and requires a small blood sample (0.02 ml). The accuracy proved 88%. 相似文献
77.
SG Dortmund 《MedR Medizinrecht》2003,21(1):56-59
Ohne Zusammenfassung 相似文献
78.
Effect of flow on polymorphonuclear leukocyte/endothelial cell adhesion 总被引:24,自引:6,他引:24
The effect of flow on the adhesion of polymorphonuclear leukocytes (PMNL) to vascular endothelium was investigated using a parallel plate chamber with a well-defined flow field. Washed PMNL were perfused over a monolayer of primary human umbilical vein endothelial cells (HUVEC) pretreated with formyl-methionyl-leucyl-phenylalanine (FMLP, 1 X 10(-7) mol/L) for five minutes. In other experiments HUVEC were pretreated with interleukin 1 (IL1,2 U/mL) for four hours. PMNL adhesion to stimulated and control HUVEC was measured over a physiologic range of wall shear stresses. PMNL adhesion to nylon-coated surface was also studied. At a wall shear stress of 0.98 dynes/cm2,283 +/- 37.3 PMNL/mm2 (mean +/- SEM) adhered to FMLP-treated HUVEC while 195 +/- 20.3 PMNL/mm2 adhered to control HUVEC. At 1.96 dynes/cm2, 68 +/- 14.1 PMNL/mm2 adhered to FMLP-treated HUVEC and 42 +/- 6.0 PMNL/mm2 adhered to control HUVEC. At 3.92 dynes/cm2, virtually no PMNL adherence was noted on either control or FMLP-treated HUVEC. On IL 1-treated HUVEC at 1.96 dynes/cm2, 371 +/- 25.8 PMNL/mm2 adhered while 28 +/- 2.9 PMNL/mm2 adhered to control HUVEC. PMNL adhesion to IL 1-treated and control HUVEC dropped to 10.2 +/- 3.8 and 6.8 +/- 3.5 PMNL/mm2, respectively, at 3.01 dynes/cm2. The effect of flow on PMNL adhesion appears to be an important factor in determining the outcome of the PMNL/HUVEC adhesive interaction under these experimental conditions. 相似文献
79.
To explore the biochemical and physiologic basis of the overlapping effects of interleukin-1 alpha (IL-1 alpha) and tumor necrosis factor alpha (TNF-alpha) on myeloid cytokine production, we have studied the dynamics of granulocyte colony-stimulating factor (G-CSF) and granulocyte-monocyte colony-stimulating factor (GM-CSF) production as well as IL-1 receptor and TNF receptor expression in a clonally derived bone marrow stromal cell strain (CDCL). IL-1 alpha and TNF alpha act in a synergistic manner to stimulate G-CSF and GM-CSF production by CDCL, resulting in an increase in CSF secretion that is 250-fold greater than that observed with either cytokine alone. This synergism in protein secretion is paralleled by synergistic increases the steady-state level of GM- and G-CSF mRNA, with supra-additive levels achieved by 24 hours. Coincident with this synergistic induction of myeloid CSFs, treatment of CDCL cells with IL-1 alpha induces a 300% increase in the expression of TNF receptors. IL-1 alpha induction of TNF receptors reaches a peak after 6 hours and gradually returns to baseline level by 24 hours. IL-1 alpha does not affect TNF receptor ligand binding affinity. A kinetic study comparing IL-1/TNF synergistic induction of growth factor secretion with IL-1 alpha induction of TNF receptors shows that these events occur in parallel. In contrast with the induction of TNF receptors by IL-1 alpha, treatment with TNF alpha has no effect on either the number of IL-1 receptors expressed by CDCL cells or IL-1 receptor ligand binding affinity. Brief treatment of IL-1 alpha/TNF alpha-stimulated CDCL cells with cycloheximide before receptor induction reduces the synergistic increase in growth factor mRNA by 40% to 60% compared with cells not treated with CHX. Taken together, these results raise the possibility that IL-1 alpha cross-induction of TNF receptors may contribute to the biochemical mechanisms underlying the synergistic stimulation of G-CSF and GM-CSF production by IL-1 alpha and TNF alpha. 相似文献
80.