全文获取类型
收费全文 | 19348篇 |
免费 | 2033篇 |
国内免费 | 44篇 |
专业分类
耳鼻咽喉 | 165篇 |
儿科学 | 543篇 |
妇产科学 | 507篇 |
基础医学 | 2617篇 |
口腔科学 | 370篇 |
临床医学 | 2163篇 |
内科学 | 3914篇 |
皮肤病学 | 188篇 |
神经病学 | 2048篇 |
特种医学 | 837篇 |
外科学 | 2799篇 |
综合类 | 369篇 |
一般理论 | 14篇 |
预防医学 | 1859篇 |
眼科学 | 281篇 |
药学 | 1200篇 |
中国医学 | 5篇 |
肿瘤学 | 1546篇 |
出版年
2021年 | 265篇 |
2020年 | 166篇 |
2019年 | 270篇 |
2018年 | 304篇 |
2017年 | 240篇 |
2016年 | 269篇 |
2015年 | 280篇 |
2014年 | 394篇 |
2013年 | 674篇 |
2012年 | 862篇 |
2011年 | 939篇 |
2010年 | 500篇 |
2009年 | 561篇 |
2008年 | 819篇 |
2007年 | 880篇 |
2006年 | 844篇 |
2005年 | 918篇 |
2004年 | 843篇 |
2003年 | 788篇 |
2002年 | 766篇 |
2001年 | 628篇 |
2000年 | 651篇 |
1999年 | 604篇 |
1998年 | 283篇 |
1997年 | 231篇 |
1996年 | 243篇 |
1995年 | 201篇 |
1994年 | 216篇 |
1993年 | 194篇 |
1992年 | 433篇 |
1991年 | 425篇 |
1990年 | 419篇 |
1989年 | 446篇 |
1988年 | 370篇 |
1987年 | 359篇 |
1986年 | 352篇 |
1985年 | 322篇 |
1984年 | 263篇 |
1983年 | 213篇 |
1982年 | 174篇 |
1981年 | 148篇 |
1980年 | 138篇 |
1979年 | 214篇 |
1978年 | 176篇 |
1977年 | 148篇 |
1976年 | 143篇 |
1974年 | 176篇 |
1973年 | 140篇 |
1972年 | 152篇 |
1971年 | 139篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
G K Hulse V Stalenberg D McCallum W Smit G O'neil N Morris R J Tait 《Journal of controlled release》2005,108(1):43-55
In order to assess the histological tissue changes over time around the site of implant, tissue biopsies were taken at 1 to 38 months post-implant from 54 (34 male) consenting human subjects who had received the Australian subcutaneous naltrexone-poly(DL-lactide) implant for heroin dependence. The implant consists of multiple tablets containing compressed naltrexone-poly[trans-3,6-dimethyl-1,4-dioxane-2,5-dione] (DL-lactide) loaded microspheres. Assessment of tissue samples by pathologists showed an early phase (up to 12 months post-implant) of inflammation, foreign body reaction, and fibrosis. This subsided gradually over the next 12 months until tissue returned to normal by 25+ months. Sufficient evidence was not available to conclude that the poly(DL-lactide) implant matrix was totally biodegradable within the study period. While implant material was not identified in most of the latter biopsies, its presence was noted in one biopsy at 26 months post-implant. Nevertheless the study results did demonstrate the implant's biocompatibility by the lack of inflammation, foreign body reaction, and fibrosis detected by 25+ months. It seems highly probable that surgical technique rather than the implant itself was associated with the additional finding of fat necrosis. Moderate fat necrosis was observed as a common feature of biopsies carried out during the first 6 months following implant. It subsided to mild levels over the next 18 months, and was notably absent by 25+ months. The results of the study indicated that the Australian naltrexone-poly(DL-lactide) implant is well tolerated and may have a role for use in the management of medical conditions such as heroin dependence. 相似文献
12.
Paul H. Lysaker Louanne W. Davis Gary J. Bryson Morris D. Bell 《Schizophrenia Research》2009,107(2-3):186-191
Designed to help persons with schizophrenia to persist and perform better at job placements, the Indianapolis Vocational Intervention Program (IVIP) is a program of cognitive-behavioral group and individual interventions. While its feasibility has been previously demonstrated, it is unknown whether IVIP assists persons to achieve greater levels of participation in vocational rehabilitation and higher levels of job performance. In this study, 100 participants with schizophrenia or schizoaffective disorder were offered a six month job placement and randomized to receive IVIP (n = 50) or support services (n = 50) matched for treatment intensity. Number of hours worked was recorded weekly and job performance was assessed biweekly using the Work Behavior Inventory with raters blind to condition. t-tests revealed that participants in the IVIP group worked a significantly greater number of weeks than those in the support condition. Also, repeated measures ANOVA revealed the IVIP group worked more hours across that 26 week period as well. And with regards to work performance, repeated measures of the 56 participants who worked for at least two-thirds of the intervention revealed that participants in the IVIP group had generally better work performance than those in the support condition. Results suggest a connection between cognitive-behavioral interventions and higher levels of work performance in people with schizophrenia. 相似文献
13.
The cytoskeleton is susceptible to oxidative stress and this occurs prior to membrane blebbing and cell lysis. Vimentin intermediary filaments in rheumatoid synoviocytes are more susceptible than in normal synoviocytes and this may have pathological significance. They are however no more susceptible to heat shock than other cell types. 相似文献
14.
INTRODUCTION: We report successful management of aortic endograft infection without graft explantation or extra-anatomic bypass. REPORT: A 66 year-old male who had undergone endovascular repair of an aortic aneurysm presented with abdominal pain and raised inflammatory markers following embolisation of a type-2 'endoleak'. CT scanning revealed a left psoas fluid collection. Endograft infection was diagnosed. Following failure of CT-guided drainage and conservative management, surgical drainage with irrigation drain placement was undertaken with preservation of the endograft. There was no evidence of recurrent infection after follow-up at 30 months. DISCUSSION: Aortic endograft infection may be managed without endograft removal and extra-anatomic bypass. 相似文献
15.
16.
Carcinoma of the gallbladder 总被引:1,自引:0,他引:1
Gallbladder carcinoma is the fourth commonest gastrointestinal malignancy. Its growth is insidious and the majority of cases are advanced at the time of diagnosis. The recognized radiological features occur only in those with advanced disease. Cholecystectomy may be curative when carcinoma is confined to the gallbladder but the place of extensive surgery, chemotherapy or radiotherapy is unproven. 相似文献
17.
18.
19.
D M Morris R Haskins A A Marino R P Misra S Rogers S Fronczak J A Albright 《Surgery》1990,107(6):627-631
Carbon in the form of 8-micron fibers induces growth of connective tissue. The purpose of this study was to measure and histologically characterize tissue ingrowth occurring in carbon fibers implanted for up to 12 months in abdominal-wall defects in rats, compared with polypropylene mesh. Carbon fibers induced significantly more tissue ingrowth than polypropylene mesh at 6 to 12 months postoperatively. The predominant tissues associated with carbon fibers and polypropylene mesh were dense connective tissue and fat, respectively. Fragmentation of the implants did not occur, and implant debris was not found in the regional lymph nodes. Carbon fibers are potentially useful for reinforcing abdominal-wall defects. 相似文献
20.
This article identifies common characteristics of educationally related programs that form a common basis for understanding and working with gifted programs. Special approaches and programs for educational enrichment as well as specific activities that have been successful are discussed. 相似文献