Between diverging discourses of the child: juveniles’ self-construction in coercive residential care

Based on a qualitative study, this article explores how Norwegian juveniles construct themselves through stories of everyday life in coercive residential care and how this is related to diverging discourses of the child’s status in society. The findings reveal two dominant positions of identification—the autonomy position and the responsibility position—which are discussed as made possible by the child-as-citizen discourse. The article argues that juveniles self-constructions primarily contrast but also are intervened with the dominant discourse of the vulnerable child in social work. The article concludes that recognising juveniles’ in residential care as citizens implies a critical evaluation of practices inherent in the discourse of the vulnerable child.     

Assessment of the Suitability of Phytotoxkit Plastic Vertical Containers Compared with Petri Dishes for Standard Seedling Growth Tests

This study compares two cultivation methods (Petri dishes vs. Phytotoxkit containers; tap water vs. Knop’s solution) for standard seedling growth tests. Seeds and young seedlings of Sinapis alba and Hordeum vulgare were used as study subjects and the adverse effect of Cd was assessed. Under testing conditions, only H. vulgare showed a significant decrease in seed germination in Petri dishes when tap water was used as the growth medium (70.8 % ± 46.4 %). No significant differences in IC₅₀ values were found in either plant type for root growth between plants cultivated in Phytotoxkit containers and those cultivated in Petri dishes. The same findings were confirmed for shoot growth in H. vulgare, but not in S. alba. Suitability of Phytotoxkit containers over traditionally used Petri dishes for phytotoxicity determination was confirmed by higher correlation coefficients for all tests.     

Rejuvenation of chondrogenic potential in a young stem cell microenvironment

Autologous cells suffer from limited cell number and senescence during ex vivo expansion for cartilage repair. Here we found that expansion on extracellular matrix (ECM) deposited by fetal synovium-derived stem cells (SDSCs) (FE) was superior to ECM deposited by adult SDSCs (AE) in promoting cell proliferation and chondrogenic potential. Unique proteins in FE might be responsible for the rejuvenation effect of FE while advantageous proteins in AE might contribute to differentiation more than to proliferation. Compared to AE, the lower elasticity of FE yielded expanded adult SDSCs with lower elasticity which could be responsible for the enhancement of chondrogenic and adipogenic differentiation. MAPK and noncanonical Wnt signals were actively involved in ECM-mediated adult SDSC rejuvenation.     

Wczesna niehematologiczna toksyczność po chemioterapii w wysokich dawkach i autologicznym przeszczepieniu komórek krwiotwórczych u chorych na nowotwory limfoidalne powyżej 60. roku życia

Early non-haematological toxicity of high dose therapy (HDT) and autologous haematopoietic cell transplantation (autoHCT) can be more hazardous in older patients (pts) with comorbidities. The aim of the study was to analyze incidence and grade of the organ-related early complications up to 30 days post-transplant period in elderly lymphoma patients. Between January 2005 and November 2011, 44 consecutive lymphoma pts underwent HDT followed by autoHCT. Median age of pts was 62 years (range 60–67). Conditioning regimens were: BEAM(carmustine, etoposide, cytarabine, melphalan) in 16, melphalan 200 in 22, cytarabine, melphalan or cyclophosphamide – in 6 pts. 32% pts had comorbidities: in 71% cardiovascular. Early non-haematologic complications within 30 days after autoHCT were reported in 84% of pts. The most common events were gastrointestinal (77%): 55% pts had prolonged (more than 7 days) diarrhoea grade III—IV, nausea and vomiting occurred in 40% of pts, 50% of pts demonstrated mucositis (grade III—IV in 34% of pts). Neutropenic fever was reported in 59% of pts with sepsis in 1.9% of pts. Cardiac events occurred in 9% of pts. Median hospitalization was 21 days (range 16—45). One patient died from transplanted related toxicity. HDT resulted in high incidence of non-hematologic toxicity in elderly patients during early post-transplant period. The toxicity of this procedure is acceptable, with mortality rate of only 2% in the elderly transplanted patients. The most common toxicities were: neutropenic fever, gastrointestinal toxicity and cardiac complications