全文获取类型
收费全文 | 8093篇 |
免费 | 307篇 |
国内免费 | 50篇 |
专业分类
耳鼻咽喉 | 74篇 |
儿科学 | 129篇 |
妇产科学 | 114篇 |
基础医学 | 971篇 |
口腔科学 | 130篇 |
临床医学 | 475篇 |
内科学 | 2304篇 |
皮肤病学 | 107篇 |
神经病学 | 590篇 |
特种医学 | 253篇 |
外科学 | 1330篇 |
综合类 | 30篇 |
一般理论 | 1篇 |
预防医学 | 158篇 |
眼科学 | 202篇 |
药学 | 629篇 |
中国医学 | 22篇 |
肿瘤学 | 931篇 |
出版年
2023年 | 36篇 |
2022年 | 76篇 |
2021年 | 157篇 |
2020年 | 82篇 |
2019年 | 106篇 |
2018年 | 107篇 |
2017年 | 100篇 |
2016年 | 148篇 |
2015年 | 156篇 |
2014年 | 218篇 |
2013年 | 269篇 |
2012年 | 431篇 |
2011年 | 496篇 |
2010年 | 239篇 |
2009年 | 221篇 |
2008年 | 409篇 |
2007年 | 472篇 |
2006年 | 448篇 |
2005年 | 462篇 |
2004年 | 473篇 |
2003年 | 443篇 |
2002年 | 467篇 |
2001年 | 156篇 |
2000年 | 185篇 |
1999年 | 218篇 |
1998年 | 97篇 |
1997年 | 92篇 |
1996年 | 92篇 |
1995年 | 79篇 |
1994年 | 78篇 |
1993年 | 95篇 |
1992年 | 133篇 |
1991年 | 104篇 |
1990年 | 93篇 |
1989年 | 106篇 |
1988年 | 96篇 |
1987年 | 85篇 |
1986年 | 58篇 |
1985年 | 76篇 |
1984年 | 61篇 |
1983年 | 64篇 |
1982年 | 37篇 |
1981年 | 34篇 |
1980年 | 30篇 |
1979年 | 52篇 |
1978年 | 28篇 |
1975年 | 23篇 |
1973年 | 23篇 |
1972年 | 22篇 |
1968年 | 26篇 |
排序方式: 共有8450条查询结果,搜索用时 31 毫秒
991.
T Hirata K Akagi S Baba F Tsurumi T Nakata T Ikeda H Doi 《Journal of cardiothoracic surgery》2012,7(1):77
ABSTRACT: Congenital pulmonary arteriovenous fistula (PAVF) is a rare disease which causes hypoxemia by shunting deoxygenated blood from the pulmonary artery into pulmonary venous return. Lung transplantation is the most effective therapy to treat severe, diffuse PAVF. However, the availability of lungs for transplantation is limited in most parts in the world. For patients with diffuse PAVF affecting only one side of the lungs, ipsilateral pulmonary artery banding (PAB) is an effective treatment, but not yet standard of care. We report successful treatment of a patient with diffuse left-sided PAVF with PAB. We believe that PAB is an effective therapy for severe unilateral PAVF and may serve as a bridge to lung transplantation. 相似文献
992.
Shiro Miyayama Masashi Yamashiro Masaya Ikuno Kennichiro Okumura Miki Yoshida 《Abdominal imaging》2014,39(3):645-656
Purpose
To analyze the technical success and tumor response of ultraselective transcatheter arterial chemoembolization (TACE) for small hepatocellular carcinoma (HCC) using automated tumor-feeders detection (AFD) software.Methods
Prototype AFD software was prospectively applied to cone-beam computed tomography images acquired during TACE for 155 consecutive HCCs ≤50 mm in 81 patients. The detectability of tumor-feeding subsubsegmental arteries was analyzed. Technical success of TACE was classified into three grades according to 1-week CT; the tumor was embolized with a safety margin (5 mm wide for tumors <25 mm, and 10 mm wide for tumors ≥25 mm) (grade A), without a margin in parts (grade B), or the entire tumor was not embolized (grade C). Tumor response at 2–3 months after TACE was also evaluated in 71 patients using the modified Response Evaluation Criteria in Solid Tumors.Results
One-hundred and twenty-eight (82.6%) tumors were classed as grade A, 17 (11%) as grade B, and 10 (6.5%) as grade C. AFD software could identify 211 (85.4%) of 247 tumor-feeders but not 36 (14.6%). Eighteen (7.9%) were false positive. The tumor response of target lesions in each patient was complete response (CR) in 49 (69%) patients, partial response (PR) in 19 (26.8%), and stable disease (SD) in 3 (4.2%). The overall tumor response was CR in 39 (54.9%) patients, PR in 15 (21.2%), SD in 1 (1.4%), and progressive disease in 16 (22.5%).Conclusions
AFD software has sufficient performance to identify tumor-feeders and contributes to the high technical success in ultraselective TACE. 相似文献993.
Shiro Matsumoto Naohiro Sata Masaru Koizumi Alan Lefor Yoshikazu Yasuda 《Pancreatology》2013,13(3):320-323
We present three patients with T2 acinar cell carcinomas (ACC) (two of which were small) and discuss their clinical and pathological features. Case 1: A 34 year-old woman had a 2.6 cm iso- or hyperdense tumor. Enucleation was performed but final diagnosis was ACC and a pylorus preserving pancreaticoduodenectomy was performed. Case 2: A 35 year-old woman was found to have a 4.5 cm hypervascular tumor in the tail of the pancreas. Distal pancreatectomy was performed. Case 3: A 61 year-old man suffered from acute pancreatitis and was found to have an encapsulated 2.5 cm hypervascular tumor in the head of pancreas. Pylorus-preserving pancreaticoduodenectomy was performed. These three patients with T2 ACCs had common characteristics including well-demarcated exophytic tumors with slow and limited progress, distinctively different from large ACCs and pancreatic ductal adenocarcinomas. ACCs are important in the differential diagnosis of homogeneously or heterogeneously enhancing small pancreatic tumors. 相似文献
994.
Takahiro Ochi Takashi Sawai Kenya Murakami Akihisa Kamataki Miwa Uzuki Tetsuya Tomita 《Modern rheumatology / the Japan Rheumatism Association》2013,23(3):401-405
AbstractNurse-like cells (NLCs) established from bone marrow and synovial tissue of rheumatoid arthritis (RA) patients were found to promote maturation and differentiation of B lineage cells as well as T cells. In co-culture of RA-NLCs and B cells, tight physical interactions (pseudoemperipolesis) developed, which resulted in activation of both cell types. RA-NLCs also supported myeloid cell maturation, promoting their differentiation into tartrate-resistant acid phosphatase-positive mononuclear cells, which are precursor cells of osteoclasts. In RA synovial tissue, the characteristic dendritic-shaped cells (the DCs) were electron microscopically found to form direct physical interactions with adjacent plasma cells (PCs) suspecting to be pseudoemperipolesis. The numbers of PCs accumulating in various areas tended to correlate with the numbers of the DCs, which appeared to have RA-NLC functions forming survival niches for PCs. Immunohistochemical staining analysis indicated that CD14+ cells including the DCs formed survival niches for CD138+ PCs by RA-NLC functions. Quantitative dual immunofluorescence staining studies of these areas indicated that the majority of CD14+ cells were of myeloid lineage. These survival niches promoted by RA-NLCs appear to play important roles in supporting immunological functions in RA bone marrow and synovial tissues. 相似文献
995.
996.
997.
998.
Tatsunori Miyata Masayuki Watanabe Yohei Nagai Masaaki Iwatsuki Shiro Iwagami Yoshifumi Baba Chiyo Furushou Yoshihiro Ikuta Tatsuro Yamamoto Hideo Baba 《Esophagus》2013,10(1):27-29
A 63-year-old man with esophageal achalasia for more than 20 years complained of respiratory distress. He was admitted as an emergency to the referral hospital three months previously. Computed tomography revealed tracheobronchial stenosis due to advanced esophageal cancer with tracheal invasion. He underwent tracheobronchial stenting and chemoradiotherapy. A large tracheoesophageal fistula (TEF) developed after irradiation (18 Gy) and chemotherapy, and he was unable to eat. Thereafter, he was referred to our hospital, where we performed esophageal bypass surgery using a gastric conduit. A percutaneous cardiopulmonary support system was prepared due to the risk of airway obstruction during anesthesia. A small-diameter tracheal tube inserted into the stent achieved ordinary respiratory management. No anesthesia-related problems were encountered. Oral intake commenced on postoperative day 9. He was discharged on postoperative day 23 and was able to take in sustenance orally right up to the last moment of his life. Esophageal bypass under general anesthesia can be performed in patients with large TEF with sufficient preparation for anesthetic management. 相似文献
999.
Takashi Kadowaki Asahiro Morishita Toshiro Niki Junko Hara Miwa Sato Joji Tani Hisaaki Miyoshi Hirohito Yoneyama Tsutomu Masaki Toshio Hattori Akihiro Matsukawa Mitsuomi Hirashima 《Critical care (London, England)》2013,17(6):R284