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排序方式: 共有931条查询结果,搜索用时 31 毫秒
31.
Mirella M. Nascimento Belmiro C. Vasconcelos Gabriela G. Porto Greiciane Ferdinanda Cyntia M. Nogueira Ronaldo C. Raimundo 《Medicina oral, patología oral y cirugía bucal》2013,18(1):e81-e85
Purpose: the aim of this study was to evaluate the use of physical therapy and anesthetic blockage of the auriculotemporal nerve as a treatment for temporomandibular joint disorders.
Methods: the sample comprised of twenty patients with a diagnosis of disc displacement with/ without reduction and arthralgia according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD Axis I Group IIa, IIb and IIIa). Ten patients (group 1) underwent a cycle of eight anesthetic blockages of the auriculotemporal nerve with injections (1 per week) of 1 ml of bupivacaine 0.5% without vasoconstrictor for 8 weeks. The other 10 patients (group 2) received anesthetic blockage and physical therapy (massage and muscular stretching exercises). After the end of treatment all patients were evaluated at baseline, 1st week, 4th week and 2 months. The t-Student and F (ANOVA) tests were used for statistical analysis, with a significance rate of 5%.
Results: there was a significant difference when both groups were compared according to VAS score (p=0.027). There was no significant difference for the other variables: MMO and jaw protrusion.
Conclusion: the anesthetic blockage and physical therapy, when used together, are effective in the reduction of pain in patients with TMD.
Key words:Temporomandibular joint disorders, physical therapy, physiotherapy and nerve block, local anesthetic, bupivacaine. 相似文献
32.
Daniele Pastori Evaristo Ettorre Gregory Y.H. Lip Angela Sciacqua Francesco Perticone Francesco Melillo Cosmo Godino Rossella Marcucci Martina Berteotti Francesco Violi Pasquale Pignatelli Mirella Saliola Danilo Menichelli Marco Antonio Casciaro Vito Menafra 《British journal of clinical pharmacology》2020,86(12):2455
33.
Neuhaus Emily Kang Veronica Youn Kresse Anna Corrigan Sarah Aylward Elizabeth Bernier Raphael Bookheimer Susan Dapretto Mirella Jack Allison Jeste Shafali McPartland James C. Van Horn John D. Pelphrey Kevin Webb Sara Jane 《Journal of autism and developmental disorders》2022,52(1):454-462
Journal of Autism and Developmental Disorders - Aggressive behaviors are common among youth with autism spectrum disorder (ASD) and correlate with pervasive social-emotional difficulties.... 相似文献
34.
Colli A Colucci A Paggi S Fraquelli M Massironi S Andreoletti M Michela V Conte D 《World journal of gastroenterology : WJG》2005,11(46):7318-7322
AIM: To assess the accuracy of a model in diagnosing severe fibrosis/cirrhosis in chronic hepatitis C virus (HCV) infection. METHODS: The model, based on the sequential combination of the Bonacini score (BS: ALT/AST ratio, platelet count and INR) and ultrasonography liver surface characteristics, was applied to 176 patients with chronic HCV infection. Assuming a pre-test probability of 35%, the model defined four levels of post-test probability of severe fibrosis/cirrhosis: <10% (low), 10-74% (not diagnostic), 75-90% (high) and >90% (almost absolute). The predicted probabilities were compared with the observed patients' distribution according to the histology (METAVIR). RESULTS: Severe fibrosis/cirrhosis was found in 67 patients (38%). The model discriminated patients in three comparable groups: 34% with a very high (>90%) or low (<10%) probability of severe fibrosis, 33% with a probability ranging from 75% to 90%, and 33% with an uncertain diagnosis (i.e., a probability ranging from 10% to 74%). The observed frequency of severe fibrosis/ cirrhosis was within the predefined ranges. CONCLUSION: The model can correctly identify 67% of patients with a high (>75%) or low (<10%) probability of cirrhosis, leaving only 33% of the patients still requiring liver biopsy. 相似文献
35.
Sarah Tosato Martina Zanoni Chiara Bonetto Federica Tozzi Clyde Francks Elisa Ira Simona Tomassi Mariaelena Bertani Dan Rujescu Ina Giegling David St Clair Michele Tansella Mirella Ruggeri Pierandrea Muglia 《Neuromolecular medicine》2014,16(4):742-751
Neuregulin 1 (NRG1) and v-erb-a erythroblastic leukemia viral oncogene homolog 4 (ErbB4) have been extensively studied in schizophrenia susceptibility because of their pivotal role in key neurodevelopmental processes. One of the reasons for the inconsistencies in results could be the fact that the phenotype investigated has mostly the diagnosis of schizophrenia per se, which is widely heterogeneous, both clinically and biologically. In the present study we tested, in a large cohort of 461 schizophrenia patients recruited in Scotland, whether several SNPs in NRG1 and/or ErbB4 are associated with schizophrenia symptom dimensions as evaluated by the Positive and Negative Syndrome Scale (PANSS). We then followed up nominally significant results in a second cohort of 439 schizophrenia subjects recruited in Germany. Using linear regression, we observed two different groups of polymorphisms in NRG1 gene: one showing a nominal association with higher scores of the PANSS positive dimension and the other one with higher scores of the PANSS negative dimension. Regarding ErbB4, a small cluster located in the 5′ end of the gene was detected, showing nominal association mainly with negative, general and total dimensions of the PANSS. These findings suggest that some regions of NRG1 and ErbB4 are functionally involved in biological processes that underlie some of the phenotypic manifestations of schizophrenia. Because of the lack of significant association after correction for multiple testing, our analyses should be considered as exploratory and hypothesis generating for future studies. 相似文献
36.
Andrea Mazzanti Ajita Kanthan Nicola Monteforte Mirella Memmi Raffaella Bloise Valeria Novelli Carlotta Miceli Sean O'Rourke Gianluca Borio Agnieszka Zienciuk-Krajka Antonio Curcio Andreea Elena Surducan Mario Colombo Carlo Napolitano Silvia G. Priori 《Journal of the American College of Cardiology》2014
37.
Stefano Molica Diana Giannarelli Luciano Levato Rosanna Mirabelli Massimo Gentile Mirella Lentini Fortunato Morabito 《International journal of hematology》2014,100(3):290-295
We propose an algorithm based on a slightly modified version of MD Anderson Cancer Center (MDACC) score (i.e., mutational status of IgVH, LDH, presence of high-risk FISH abnormalities), β2-microglobulin and separation of clinical monoclonal B-cell lymphocytosis (cMBL) from chronic lymphocytic leukemia (CLL) to predict time to first treatment (TTFT) of a prospective multicentre cohort including 83 cMBL and 136 CLL Rai stage 0 patients. Patients with MDACC score point ≥38, at any level of β2-microglobulin and irrespective of whether they fulfilled 2008 International Workshop on CLL (IWCLL) criteria for CLL Rai stage 0 or cMBL, experienced the worst clinical outcome (5-year TTFT, 24 %) and formed the high-risk group. In contrast, subjects with a diagnosis of cMBL, MDACC score point <38 and β2-microglobulin ≤ UNL had the best clinical outcome (5-year TTFT, 100 %) and constituted the low-risk group. The intermediate group included patients in Rai stage 0, MDACC score point <38, and any level of β2-microglobulin, and patients with cMBL, MDACC score point <38, and β2-microglobulin ≥ UNL. Cases showing these features can be grouped together to form the intermediate-risk group (5-year TTFT, 65 %). Although the separation between cMBL and Rai stage 0, as proposed by the 2008 IWCLL guidelines, has clinical implications, the model we propose may help to classify patients with cMBL and Rai stage 0 into more precise subgroups suggesting that a prognostic separation of these entities based solely on clonal B-cell threshold may be unsatisfactory. 相似文献
38.
39.
Definition of minimal duplicated region encompassing the XIAP and STAG2 genes in the Xq25 microduplication syndrome
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Daniela Di Benedetto Sebastiano Antonino Musumeci Emanuela Avola Antonino Alberti Serafino Buono Carmela Scuderi Lucia Grillo Ornella Galesi Angela Spalletta Mariangela Lo Giudice Daniela Luciano Mirella Vinci Sebastiano Bianca Corrado Romano Marco Fichera 《American journal of medical genetics. Part A》2014,164(8):1923-1930
40.
The need for water security pushes for the development of sensing technologies that allow online and real-time assessments and are capable of autonomous and stable long-term operation in the field. In this context, Microbial Fuel Cell (MFC) based biosensors have shown great potential due to cost-effectiveness, simplicity of operation, robustness and the possibility of self-powered applications. This review focuses on the progress of the technology in real scenarios and in-field applications and discusses the technological bottlenecks that must be overcome for its success. An overview of the most relevant findings and challenges of MFC sensors for practical implementation is provided. First, performance indicators for in-field applications, which may diverge from lab-based only studies, are defined. Progress on MFC designs for off-grid monitoring of water quality is then presented with a focus on solutions that enhance robustness and long-term stability. Finally, calibration methods and detection algorithms for applications in real scenarios are discussed.Overview of challenges and opportunities in microbial fuel cells for in-field operation. 相似文献