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排序方式: 共有10000条查询结果,搜索用时 46 毫秒
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Ewout S. Veltman Michel P.J. van den Bekerom Job N. Doornberg Diederik O. Verbeek Stefan Rammelt Ernst Ph. Steller Tim Schepers 《Injury》2014
This study determined inter- and intra-observer reliability for measurement of the angles of Böhler and Gissane, for the decision between surgical or conservative management and for the three mostly used classification systems for calcaneal fractures with the use of 2D-CT imaging versus 2D- and 3D-CT imaging. 相似文献
997.
Michel A Pontari 《Asian journal of andrology》2014,16(5):784-784
Vicari et al. present the results of using rifaximn, a nonabsorbable antibiotic, and the probiotic VSL#3 in infertile men with bacteria in the semen and leukocytes in the expressed prostatic secretions (EPS) who were initially cured by antibiotics. Use of this combination reduces the recurrence rate of the infection as well as sonographic evidence of spread to other parts of the reproductive tract. The theoretical basis for simultaneous treatment of the genitourinary and gastrointestinal tract has become more compelling given the evidence of overlapping innervation of the colon and bladder, and influence of inflammation in one organ on the other. These results are very promising and intriguing, but it is very important to keep clear the outcome measures in this study. The outcome parameters were related to the effects on sperm cultures, leukocytes in the EPS and ultrasonographic findings in the seminal vesicles and epididymis. A tender prostate was also considered a positive sign. Symptoms of "prostatitis" as with the National Institutes of Health Chronic Prostatitis Symptom Index were not assessed. 相似文献
998.
Michel Lucas Eilis J. O’Reilly An Pan Fariba Mirzaei Walter C. Willett Olivia I. Okereke 《The world journal of biological psychiatry》2014,15(5):377-386
Objective.To evaluate the association between coffee and caffeine consumption and suicide risk in three large-scale cohorts of US men and women. Methods. We accessed data of 43,599 men enrolled in the Health Professionals Follow-up Study (HPFS, 1988–2008), 73,820 women in the Nurses’ Health Study (NHS, 1992–2008), and 91,005 women in the NHS II (1993–2007). Consumption of caffeine, coffee, and decaffeinated coffee, was assessed every 4 years by validated food-frequency questionnaires. Deaths from suicide were determined by physician review of death certificates. Multivariate adjusted relative risks (RRs) were estimated with Cox proportional hazard models. Cohort specific RRs were pooled using random-effect models. Results. We documented 277 deaths from suicide. Compared to those consuming ≤ 1 cup/week of caffeinated coffee (< 8 oz/237 ml), the pooled multivariate RR (95% confidence interval [CI]) of suicide was 0.55 (0.38–0.78) for those consuming 2–3 cups/day and 0.47 (0.27–0.81) for those consuming ≥ 4 cups/day (P trend < 0.001). The pooled multivariate RR (95% CI) for suicide was 0.75 (0.63–0.90) for each increment of 2 cups/day of caffeinated coffee and 0.77 (0.63–0.93) for each increment of 300 mg/day of caffeine. Conclusions. These results from three large cohorts support an association between caffeine consumption and lower risk of suicide. 相似文献
999.
Gilles Klein Lothar Burghaus Michel Vaillant Vannina Pieri Gereon R. Fink Nico Diederich 《JOURNAL OF CLINICAL NEUROLOGY》2014,10(4):314-319
Background and Purpose
Excessive daytime sleepiness and sudden sleep attacks are the main features of narcolepsy, but rapid-eye-movement sleep behavior disorder (RBD), hyposmia, and depression can also occur. The latter symptoms are nonmotor features in idiopathic Parkinson''s disease (IPD). In the present study, IPD-proven diagnostic tools were tested to determine whether they are also applicable in the assessment of narcolepsy.Methods
This was a case-control study comparing 15 patients with narcolepsy (PN) and 15 control subjects (CS) using the Scales for Outcomes in Parkinson''s Autonomic Test (SCOPA-AUT), Parkinson''s Disease Nonmotor Symptoms (PDNMS), University of Pennsylvania Smell Test, Farnsworth-Munsell 100 Hue test, Beck Depression Inventory, and the RBD screening questionnaire.Results
Both the PN and CS exhibited mild hyposmia and no deficits in visual tests. Frequent dysautonomia in all domains except sexuality was found for the PN. The total SCOPA-AUT score was higher for the PN (18.47±10.08, mean±SD) than for the CS (4.40±3.09), as was the PDNMS score (10.53±4.78 and 1.80±2.31, respectively). RBD was present in 87% of the PN and 0% of the CS. The PN were more depressed than the CS. The differences between the PN and CS for all of these variables were statistically significant (all p<0.05).Conclusions
The results of this study provide evidence for the presence of dysautonomia and confirm the comorbidities of depression and RBD in narcolepsy patients. The spectrum, which is comparable to the nonmotor complex in IPD, suggests wide-ranging, clinically detectable dysfunction beyond the narcoleptic core syndrome. 相似文献1000.