全文获取类型
收费全文 | 8070篇 |
免费 | 434篇 |
国内免费 | 56篇 |
专业分类
耳鼻咽喉 | 60篇 |
儿科学 | 230篇 |
妇产科学 | 124篇 |
基础医学 | 1016篇 |
口腔科学 | 186篇 |
临床医学 | 599篇 |
内科学 | 2024篇 |
皮肤病学 | 247篇 |
神经病学 | 571篇 |
特种医学 | 350篇 |
外科学 | 1159篇 |
综合类 | 36篇 |
预防医学 | 299篇 |
眼科学 | 150篇 |
药学 | 634篇 |
中国医学 | 19篇 |
肿瘤学 | 856篇 |
出版年
2023年 | 44篇 |
2022年 | 88篇 |
2021年 | 144篇 |
2020年 | 105篇 |
2019年 | 139篇 |
2018年 | 158篇 |
2017年 | 106篇 |
2016年 | 158篇 |
2015年 | 184篇 |
2014年 | 209篇 |
2013年 | 260篇 |
2012年 | 441篇 |
2011年 | 487篇 |
2010年 | 277篇 |
2009年 | 246篇 |
2008年 | 420篇 |
2007年 | 409篇 |
2006年 | 426篇 |
2005年 | 402篇 |
2004年 | 409篇 |
2003年 | 362篇 |
2002年 | 409篇 |
2001年 | 247篇 |
2000年 | 247篇 |
1999年 | 230篇 |
1998年 | 96篇 |
1997年 | 90篇 |
1996年 | 89篇 |
1995年 | 57篇 |
1994年 | 64篇 |
1993年 | 47篇 |
1992年 | 162篇 |
1991年 | 149篇 |
1990年 | 124篇 |
1989年 | 146篇 |
1988年 | 101篇 |
1987年 | 93篇 |
1986年 | 90篇 |
1985年 | 84篇 |
1984年 | 68篇 |
1983年 | 53篇 |
1982年 | 26篇 |
1979年 | 55篇 |
1978年 | 31篇 |
1977年 | 36篇 |
1976年 | 25篇 |
1974年 | 26篇 |
1972年 | 25篇 |
1971年 | 22篇 |
1970年 | 26篇 |
排序方式: 共有8560条查询结果,搜索用时 15 毫秒
21.
22.
Katsumi Harasawa Osamu Kemmotsu Takahisa Mayumi Yoshiteru Kawano 《Journal of clinical monitoring and computing》1997,13(1):19-24
Objective. Tympanic temperature can be obtained instantaneously using an infrared emission detection (IRED) thermometer. Its accuracy has been documented in a variety of clinical settings, but its performance at low body temperatures is still unknown. In this study we evaluated its performance during coronary artery revascularization surgery in which mild hypothermic cardiopulmonary bypass (CPB) was used. Methods. Thirty adult patients undergoing coronary artery bypass graft surgery were enrolled in the study. Tympanic temperature obtained using IRED thermometry (Tt1) was compared with core temperatures from the esophagus (Te), and venous blood of CPB (Tv) before, during, and after CPB. We also measured tympanic temperature using a thermocouple probe (Tt2) in 16 of the 30 patients in order to study the agreement between the two methods. Values for correlation coefficients and limits of agreement were computed to assess the degree of agreement among the temperatures obtained. Results. The highest agreement with Tv during CPB was obtained from Tt1 (r = 0.94, 0.41 ± 1.73, limits of agreement) and from Te (0.91, 0.36 ± 2.46). Tt1 also showed good agreement with Tt2 during surgery. Conclusions. Infrared tympanic thermometry is a reliable, alternative method to measure tympanic temperature and may be useful to assess core temperature in both normothermic and mild hypothermic conditions. 相似文献
23.
24.
F Omata Y Ichikawa Y Kushibiki H Shimizu M Yoshida M Komatsuda S Arimori 《American journal of hematology》1992,40(2):160-161
25.
T Ohashi F Yamamoto H Yamamoto H Ichikawa T Shibata Y Shimada T Ishikawa K Kagisaki Y Kumada Y Kawashima 《[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai》1992,40(11):1998-2004
The effects of potassium in reperfusion solution (RS) and the influence of sodium on this effect were studied. Experimental time course was as followed: 20 min working perfusion, 3 min cardioplegic infusion with St. Thomas Cardioplegic Solution followed by global ischemia for 33 or 35 min at 37.5 degrees C, 15 min early Langendorff reperfusion with several different potassium concentration modified with Krebs Henseleit Bicarbonate Buffer (KHBB) containing 145 mM and 110 mM sodium and 5 min late reperfusion with KHBB, followed by 20 min working perfusion. Potassium in RS possessed bell shaped dose response nature with optimal concentration of 10 mM in the condition of 145 mM sodium but 6 m in the condition of 110 mM in terms of percent recovery of aortic flow. Although higher potassium reperfusion produced less Creatine Kinase leakage. 相似文献
26.
27.
Inhibitory action of tranilast, an anti-allergic drug, on the release of cytokines and PGE2 from human monocytes-macrophages. 总被引:1,自引:0,他引:1
Tranilast, an anti-allergic drug that inhibits the release of substances such as histamine and prostaglandins from mast cells, has been reported to improve keloids and hypertrophic scars which originate from the abnormal proliferation and excessive collagen accumulation of fibroblasts. It has been considered that various chemical mediators produced by inflammatory cells play important roles in the development of keloids and hypertrophic scars. We therefore studied the effect of tranilast on the release of chemical mediators including transforming growth factor (TGF)-beta 1, interleukin (IL)-1 beta and prostaglandin (PG) E2 which are produced by the human monocytes-macrophages, and estimated whether these mediators induce collagen synthesis and cell proliferation of normal skin fibroblasts. Tranilast inhibited the release of TGF-beta 1, IL-1 beta and PGE2 from the human monocytes-macrophages. TGF-beta 1 (25-200 pM) enhanced the collagen synthesis by fibroblasts. IL-1 (0.1-1 U/ml) increased the proliferation and conversely decreased the collagen synthesis. PGE2 (2 micrograms/ml) enhanced the collagen synthesis. These results suggest that tranilast suppresses collagen synthesis by fibroblasts through inhibiting TGF-beta 1 and PGE2 production and cell proliferation by fibroblasts through inhibiting IL-1 production by inflammatory cells such as macrophages. 相似文献
28.
Junichi Taki Akihiro Ichikawa Kenichi Nakajima Michio Kawasuji Norihisa Tonami 《European journal of nuclear medicine and molecular imaging》1997,24(12):1487-1493
Stress thallium-201 tomography was performed to compare the flow capacities of arterial and saphenous vein grafts in patients
with coronary artery bypass grafting (CABG). One hundred and seven consecutive patients (95 male and 12 female; mean age 58±9.1
years) underwent exercise-redistribution 201Tl myocardial single-photon emission tomography 4–5 weeks after CABG. When a reversible perfusion defect was present in the
area covered by a patent bypass graft, the flow capacity of the graft was defined as insufficient. Of all 285 grafts, 211
were considered as complete bypass. Reversible perfusion defects were present in 29 (27%) of 108 myocardial areas supplied
by patent arterial grafts but in only 5 (5%) of 103 myocardial areas supplied by patent saphenous vein grafts (P<0.0001). In the LAD area reversible defects were observed in 22 of 82 areas covered by arterial grafts, in contrast to only
1 of 29 areas covered by venous grafts (P<0.01); in the RCA area reversible defects were observed in 7 of 17 and 4 of 41 areas respectively (P<0.01). There was no difference between the native coronary artery stenosis bypassed by patent arterial and venous grafts
(88%±12% vs 86%±14% respectively, P=0.27). In conclusion, flow capacities during peak myocardial demand were more frequently insufficient in arterial bypass
grafts than in saphenous vein grafts.
Received 23 May and in revised form 7 August 1997 相似文献
29.
S Nagano N Fujimoto M Kyo Y Ichikawa M Ishibashi S Takahara H Ihara M Nojima Y Kato A Hirano 《Hinyokika kiyo. Acta urologica Japonica》1992,38(9):1083-1088
A statistic analysis was carried out on the 4,956 inpatients admitted to our Department of Urology from April 1972 to December 1991. The patients included 3,399 males and 1,557 females. A total of 4,105 operations including 255 renal allotransplantations were performed on 3,590 patients. Open surgery for upper urinary tract stones has been replaced by extracorporeal shock-wave lithotripsy (ESWL) in the last three years. 相似文献
30.