全文获取类型
收费全文 | 9248篇 |
免费 | 626篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 170篇 |
儿科学 | 257篇 |
妇产科学 | 190篇 |
基础医学 | 1042篇 |
口腔科学 | 197篇 |
临床医学 | 1100篇 |
内科学 | 1707篇 |
皮肤病学 | 129篇 |
神经病学 | 780篇 |
特种医学 | 241篇 |
外国民族医学 | 2篇 |
外科学 | 1415篇 |
综合类 | 163篇 |
一般理论 | 12篇 |
预防医学 | 1043篇 |
眼科学 | 257篇 |
药学 | 669篇 |
中国医学 | 24篇 |
肿瘤学 | 499篇 |
出版年
2023年 | 52篇 |
2022年 | 102篇 |
2021年 | 227篇 |
2020年 | 135篇 |
2019年 | 174篇 |
2018年 | 195篇 |
2017年 | 148篇 |
2016年 | 169篇 |
2015年 | 218篇 |
2014年 | 315篇 |
2013年 | 411篇 |
2012年 | 561篇 |
2011年 | 530篇 |
2010年 | 294篇 |
2009年 | 267篇 |
2008年 | 475篇 |
2007年 | 450篇 |
2006年 | 402篇 |
2005年 | 437篇 |
2004年 | 360篇 |
2003年 | 341篇 |
2002年 | 326篇 |
2001年 | 230篇 |
2000年 | 249篇 |
1999年 | 235篇 |
1998年 | 87篇 |
1997年 | 74篇 |
1996年 | 66篇 |
1995年 | 67篇 |
1994年 | 64篇 |
1993年 | 50篇 |
1992年 | 143篇 |
1991年 | 131篇 |
1990年 | 156篇 |
1989年 | 106篇 |
1988年 | 118篇 |
1987年 | 116篇 |
1986年 | 102篇 |
1985年 | 109篇 |
1984年 | 84篇 |
1983年 | 75篇 |
1982年 | 64篇 |
1979年 | 80篇 |
1978年 | 67篇 |
1975年 | 54篇 |
1974年 | 48篇 |
1973年 | 65篇 |
1972年 | 56篇 |
1971年 | 53篇 |
1969年 | 58篇 |
排序方式: 共有9897条查询结果,搜索用时 15 毫秒
1.
C. Jacquet F. Goehringer E. Baux J.A. Conrad M.O. Ganne Devonec J.L. Schmutz G. Mathey H. Tronel T. Moulinet I. Chary-Valckenaere T. May C. Rabaud 《Médecine et maladies infectieuses》2019,49(2):112-120
Objective
The teaching hospital of Nancy, France, implemented a specific multidisciplinary care pathway (French acronym AMDPL) to improve the management of patients presenting with Lyme borreliosis (LB) suspicion. We aimed to assess the first year of activity of this care pathway.Patients and methods
We included all patients managed in the AMDPL pathway from November 1, 2016 to October 31, 2017. The first step was a dedicated Lyme disease consultation with an infectious disease specialist. Following this consultation, the LB diagnosis was either confirmed and adequate treatment was prescribed, or a differential diagnosis was established and patients received adequate management, or further investigations were required and patients were offered multidisciplinary management as part of a day hospitalization.Results
A total of 468 patients were included. LB diagnosis was confirmed in 15% of patients (69/468), 49% of patients received a differential diagnosis, and 26% (122/468) of patients had the LB diagnosis ruled out without receiving any other diagnosis.Conclusions
This is to our knowledge the first multidisciplinary center implemented in France for the management of patients presenting with LB suspicion related to polymorphous signs and symptoms. Several diagnoses could be confirmed or corrected, although some symptoms and complaints could not be explained. This cohort could improve our knowledge of LB and its differential diagnoses. 相似文献2.
3.
Prevalence of Potentially Inappropriate Prescribing Among Hong Kong Older Adults: A Comparison of the Beers 2003, Beers 2012, and Screening Tool of Older Person's Prescriptions and Screening Tool to Alert doctors to Right Treatment Criteria 下载免费PDF全文
4.
5.
The effect of bracing on proprioception of knees with anterior cruciate ligament injury. 总被引:2,自引:0,他引:2
Bruce D Beynnon Lars Good May Arna Risberg 《The Journal of orthopaedic and sports physical therapy》2002,32(1):11-15
This paper is a comprehensive review on the effect of bandaging, bracing, and neoprene sleeves on knee proprioception following anterior cruciate ligament (ACL) injury and reconstruction with a focus on studies that have measured joint position sense and threshold to detection of passive knee motion. Disruption of the ACL does not appear to alter joint position sense soon after injury, although there is evidence that in some subjects deterioration may occur over time. An ACL tear creates a deficit in the threshold to detection of passive knee motion soon after injury and in those with chronic tears. The magnitude of worsening is less then 1.0 degree of movement in flexion-extension and of questionable concern from a clinical and functional perspective. Application of a functional brace or neoprene sleeve to the ACL-deficient limb does not improve the threshold to detection of passive knee motion; however, application of an elastic bandage to a knee with an ACL tear improves joint position sense. Reconstruction of a torn ACL is associated with a deficit in the threshold to detection of passive knee motion, and during the first year of healing the use of a neoprene sleeve provides improvement. Two years following ACL reconstruction there is no deficit in the threshold to detection of passive knee motion and the use of a brace has no effect on this outcome. 相似文献
6.
7.
8.
The interpretation of the total phenytoin (PT) concentration can be problematic if valproic acid (VPA) is given as a comedication, because VPA displaces PT from the protein binding sites and can increase the free fraction of PT. In order to estimate the free or unbound PT concentration (PTf) from the total PT concentration (PTt) and VPA concentration, a nomogram was constructed and evaluated. Data of 84 patients on combined therapy with PT and VPA were used in drawing up the regression equation (PTf = 0.0792.PTt + 0.000636.PTt.VPA) from which the nomogram was constructed. The predictions were checked using another 33 patients whose serum concentrations were determined in the morning and in addition several times during the day. The results show that using this method the PTf concentrations can be accurately estimated from the PTt and VPA concentrations. 相似文献
9.
G?khan Tun?bilek Serdar Nasir Omer Ozkan Aycan Kayik?io?lu Emin Mavili 《Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi》2004,38(2):94-99
Defects in the sacrococcygeal and ischial soft tissues can be treated with gluteus maximus and posterior thigh V-Y advancement flaps. However, late complications include recurrence and dehiscence of the suture line. Increasing the amount of the soft tissues over the bony prominences and multilayered closure may have an advantage for long-term durability. We modified the V-Y advancement technique by de-epithelialising the medial parts of the flap and burying them under the opposing edge of the wound or the flap. Sixteen patients with various defects of the sacrococcygeal and ischial soft tissues were operated on using this technique. All the flaps healed well with no partial or complete loss of the flap. Three patients developed complications. The main advantage of our technique is the use of healthy tissues to obliterate the dead spaces under the edges of the wound or the opposing flap. In this way, not only the defect in the skin but the defect in the subcutaneous tissue, with its iceberg tip at the surface, is treated effectively. To have an additional layer of tissue between the bone and the superficial tissues provides an extra cushion of soft tissue and avoids putting the suture line directly over the bony prominences. We used this modification safely for both unilateral and bilateral flaps. It could also be used successfully in other parts of the body. 相似文献
10.
The effect of prolonged, 22 h long, intracerebroventricular (i.c.v.) infusion of corticotropin-releasing hormone (CRF) on plasma cortisol, corticosterone and electrolyte concentrations, mean arterial blood pressure (MAP) and heart rate (HR) were investigated in conscious rabbits. During i.c.v. infusion of CRF, 1 and 3 μ/h, at a rate of 17 μl/h, plasma cortisol and corticosterone concentrations rose to the level noted after ACTH stimulation in rabbits. Plasma [Na] did not change, but plasma [K] was reduced and plasma osmolality increased during the infusion of CRF, 3 μ/h. MAP and HR, recorded continuously during i.c.v. infusion of CRF, changed only with the higher dose of CRF: MAP was elevated during the first 5 h of infusion, and then returned to the control level. HR was lower than control at the end of the first hour of infusion and again between 9 and 15 h of infusion. The prolonged rise of CRF concentration in the brain induced a sustained rise in circulating adrenal steroid hormones. MAP did not increase to the level noted after bolus i.c.v. injection of CRF and the rise in MAP was not sustained. 相似文献