全文获取类型
收费全文 | 237650篇 |
免费 | 10573篇 |
国内免费 | 634篇 |
专业分类
耳鼻咽喉 | 3067篇 |
儿科学 | 7202篇 |
妇产科学 | 5960篇 |
基础医学 | 34138篇 |
口腔科学 | 7449篇 |
临床医学 | 15268篇 |
内科学 | 53315篇 |
皮肤病学 | 7218篇 |
神经病学 | 19767篇 |
特种医学 | 5912篇 |
外国民族医学 | 30篇 |
外科学 | 28097篇 |
综合类 | 1157篇 |
一般理论 | 45篇 |
预防医学 | 25560篇 |
眼科学 | 5539篇 |
药学 | 17817篇 |
中国医学 | 885篇 |
肿瘤学 | 10431篇 |
出版年
2023年 | 1295篇 |
2022年 | 2131篇 |
2021年 | 4953篇 |
2020年 | 2682篇 |
2019年 | 4815篇 |
2018年 | 6808篇 |
2017年 | 4354篇 |
2016年 | 4564篇 |
2015年 | 4999篇 |
2014年 | 6308篇 |
2013年 | 9189篇 |
2012年 | 14396篇 |
2011年 | 14991篇 |
2010年 | 8000篇 |
2009年 | 6589篇 |
2008年 | 12264篇 |
2007年 | 12934篇 |
2006年 | 12430篇 |
2005年 | 12102篇 |
2004年 | 11128篇 |
2003年 | 10331篇 |
2002年 | 9949篇 |
2001年 | 6894篇 |
2000年 | 7414篇 |
1999年 | 5993篇 |
1998年 | 1569篇 |
1997年 | 1131篇 |
1996年 | 1030篇 |
1992年 | 3129篇 |
1991年 | 2907篇 |
1990年 | 2851篇 |
1989年 | 2468篇 |
1988年 | 2297篇 |
1987年 | 2149篇 |
1986年 | 2163篇 |
1985年 | 2012篇 |
1984年 | 1481篇 |
1983年 | 1298篇 |
1979年 | 1590篇 |
1978年 | 1071篇 |
1975年 | 1156篇 |
1974年 | 1437篇 |
1973年 | 1465篇 |
1972年 | 1377篇 |
1971年 | 1329篇 |
1970年 | 1266篇 |
1969年 | 1325篇 |
1968年 | 1306篇 |
1967年 | 1175篇 |
1966年 | 1068篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
11.
12.
Jose M. Morales Jose Angel Martinez-Flores Manuel Serrano Maria José Castro Francisco Javier Alfaro Florencio García Miguel Angel Martínez Amado Andrés Esther González Manuel Praga Estela Paz-Artal Antonio Serrano 《Journal of the American Society of Nephrology : JASN》2015,26(3):735-745
In the current immunosuppressive therapy era, vessel thrombosis is the most common cause of early graft loss after renal transplantation. The prevalence of IgA anti–β2-glycoprotein I antibodies (IgA-aB2GPI-ab) in patients on dialysis is elevated (>30%), and these antibodies correlate with mortality and cardiovascular morbidity. To evaluate the effect of IgA-aB2GPI-ab in patients with transplants, we followed all patients transplanted from 2000 to 2002 in the Hospital 12 de Octubre prospectively for 10 years. Presence of IgA-aB2GPI-ab in pretransplant serum was examined retrospectively. Of 269 patients, 89 patients were positive for IgA-aB2GPI-ab (33%; group 1), and the remaining patients were negative (67%; group 2). Graft loss at 6 months post-transplant was significantly higher in group 1 (10 of 89 versus 3 of 180 patients in group 2; P=0.002). The most frequent cause of graft loss was thrombosis of the vessels, which was observed only in group 1 (8 of 10 versus 0 of 3 patients in group 2; P=0.04). Multivariate analysis showed that the presence of IgA-aB2GPI-ab was an independent risk factor for early graft loss (P=0.04) and delayed graft function (P=0.04). There were no significant differences regarding patient survival between the two groups. Graft survival was similar in both groups after 6 months. In conclusion, patients with pretransplant IgA-aB2GPI-ab have a high risk of early graft loss caused by thrombosis and a high risk of delayed graft function. Therefore, pretransplant IgA-aB2GPI-ab may have a detrimental effect on early clinical outcomes after renal transplantation. 相似文献
13.
Ruiz-Úcar Elena Acín-Gándara Débora Medina-García Manuel Ronda Diego Cruzado Pereira-Pérez Fernando 《Obesity surgery》2022,32(2):569-570
Obesity Surgery - Laparoscopic sleeve gastrectomy (LSG) is increasingly playing a key role in obesity management. Such operations, however, carry complications sometimes including leaks. The... 相似文献
14.
Bień Agnieszka Rzońca Ewa Zarajczyk Marta Wilkosz Katarzyna Wdowiak Artur Iwanowicz-Palus Grażyna 《Quality of life research》2020,29(10):2669-2677
Quality of Life Research - The aim of the study was to assess QoL and identify and analyse its determinants in women with endometriosis. The study was performed in 2019 in health centres in Lublin... 相似文献
15.
16.
17.
R. Di Raimondo J. Sanz-Esporrn R. Pl I. Sanz-Martn F. Luengo F. Vignoletti J. Nuez Mariano Sanz 《Clinical oral investigations》2020,24(7):2351-2361
To evaluate the changes in alveolar contour after guided bone regeneration (GBR) with two different combinations of biomaterials in dehiscence defects arou 相似文献
18.
Andres Eduardo Campuzano-García Bertha Torres-Alvarez Diana Hernández-Blanco 《Journal of cosmetic and laser therapy》2015,17(4):213-215
Hailey–Hailey disease (HHD), also known as benign familial pemphigus, is an autosomal dominant skin condition that affects the adhesion of epidermal keratinocytes. Although the initial manifestation of flaccid vesicles on erythematous or normal skin in flexure sites frequently goes unnoticed, large, macerated, exudative plaques of superficial erosions with crusting are observed at the time of diagnosis. There is no specific treatment for HHD, and most cases are symptomatically supported. However, infrared laser ablation has been somewhat helpful. We present a case successfully treated with fractional CO2 laser showing a long-term favourable outcome and no adverse effects. Thus, this modality could be an alternative to full ablation for this condition. 相似文献
19.
20.
Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean 《World journal of gastrointestinal surgery》2015,7(8):170-173
Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. 相似文献