全文获取类型
收费全文 | 1679篇 |
免费 | 118篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 40篇 |
妇产科学 | 57篇 |
基础医学 | 288篇 |
口腔科学 | 29篇 |
临床医学 | 120篇 |
内科学 | 303篇 |
皮肤病学 | 50篇 |
神经病学 | 229篇 |
特种医学 | 37篇 |
外科学 | 155篇 |
综合类 | 20篇 |
一般理论 | 1篇 |
预防医学 | 198篇 |
眼科学 | 37篇 |
药学 | 100篇 |
中国医学 | 20篇 |
肿瘤学 | 120篇 |
出版年
2024年 | 1篇 |
2023年 | 7篇 |
2022年 | 38篇 |
2021年 | 62篇 |
2020年 | 41篇 |
2019年 | 67篇 |
2018年 | 61篇 |
2017年 | 56篇 |
2016年 | 47篇 |
2015年 | 74篇 |
2014年 | 86篇 |
2013年 | 100篇 |
2012年 | 145篇 |
2011年 | 147篇 |
2010年 | 71篇 |
2009年 | 74篇 |
2008年 | 122篇 |
2007年 | 120篇 |
2006年 | 110篇 |
2005年 | 105篇 |
2004年 | 90篇 |
2003年 | 60篇 |
2002年 | 58篇 |
2001年 | 7篇 |
2000年 | 3篇 |
1999年 | 4篇 |
1998年 | 12篇 |
1997年 | 14篇 |
1996年 | 4篇 |
1995年 | 8篇 |
1994年 | 5篇 |
1993年 | 1篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 3篇 |
1988年 | 1篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1973年 | 2篇 |
1968年 | 1篇 |
1905年 | 1篇 |
排序方式: 共有1816条查询结果,搜索用时 15 毫秒
31.
32.
Evelien Platje Lucres M.C. Jansen Adrian Raine Susan J.T. Branje Theo A.H. Doreleijers Marjan de Vries-Bouw Arne Popma Pol A.C. van Lier Hans M. Koot Wim H.J. Meeus Robert R.J.M. Vermeiren 《Biological psychology》2013
Although several studies have associated antisocial behavior with decreased cortisol awakening responses (CAR), studies in adolescent samples yielded inconsistent results. In adolescence however, the CAR develops and antisocial behavior is heterogeneous in type and persistence. Therefore this longitudinal study compared persistent aggressive and rule-breaking adolescents to low aggressive and rule-breaking adolescents on the development of the CAR from ages 15 to 17 (N = 390). Persistently high aggressive adolescents showed decreased cortisol levels at awakening consistently over the years (Δχ2(1) = 6.655, p = .01) as compared to low aggressive adolescents. No differences between adolescents showing persistent high rule-breaking and low rule-breaking were found. This longitudinal study is the first to show that persistent aggression, but not rule-breaking behavior, is related to neurobiological alterations. Moreover, despite development of the CAR over adolescence, the decrease in cortisol is consistent over time in persistent high aggressive adolescents, which is an important prerequisite for the prediction of persistent aggression. 相似文献
33.
34.
Liu Gengbo Mitra Debasis Jones Ella F. Franc Benjamin L. Behr Spencer C. Nguyen Alex Bolouri Marjan S. Wisner Dorota J. Joe Bonnie N. Esserman Laura J. Hylton Nola M. Seo Youngho 《Journal of digital imaging》2021,34(3):630-636
Journal of Digital Imaging - In this proof-of-concept work, we have developed a 3D-CNN architecture that is guided by the tumor mask for classifying several patient-outcomes in breast cancer from... 相似文献
35.
Multidimensional ultrasound imaging of the wrist: Changes of shape and displacement of the median nerve and tendons in carpal tunnel syndrome
下载免费PDF全文
![点击此处可从《Journal of orthopaedic research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Anika Filius Marjan Scheltens Hans G. Bosch Pieter A. van Doorn Henk J. Stam Steven E. R. Hovius Peter C. Amadio Ruud W. Selles 《Journal of orthopaedic research》2015,33(9):1332-1340
Dynamics of structures within the carpal tunnel may alter in carpal tunnel syndrome (CTS) due to fibrotic changes and increased carpal tunnel pressure. Ultrasound can visualize these potential changes, making ultrasound potentially an accurate diagnostic tool. To study this, we imaged the carpal tunnel of 113 patients and 42 controls. CTS severity was classified according to validated clinical and nerve conduction study (NCS) classifications. Transversal and longitudinal displacement and shape (changes) were calculated for the median nerve, tendons and surrounding tissue. To predict diagnostic value binary logistic regression modeling was applied. Reduced longitudinal nerve displacement (p≤ 0.019), increased nerve cross‐sectional area (p≤ 0.006) and perimeter (p≤ 0.007), and a trend of relatively changed tendon displacements were seen in patients. Changes were more convincing when CTS was classified as more severe. Binary logistic modeling to diagnose CTS using ultrasound showed a sensitivity of 70–71% and specificity of 80–84%. In conclusion, CTS patients have altered dynamics of structures within the carpal tunnel. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 33:1332–1340, 2015. 相似文献
36.
Analysis of immune reconstitution after autologous bone marrow transplantation in systemic sclerosis 总被引:4,自引:0,他引:4
Farge D Henegar C Carmagnat M Daneshpouy M Marjanovic Z Rabian C Ilie D Douay C Mounier N Clave E Bengoufa D Cabane J Marolleau JP Gluckman E Charron D Toubert A 《Arthritis and rheumatism》2005,52(5):1555-1563
OBJECTIVE: To analyze hematopoietic and immune reconstitution after autologous hematopoietic stem cell transplantation (HSCT) in 7 patients with systemic sclerosis (SSc). METHODS: Two groups of patients were retrospectively constituted according to whether they had a favorable clinical response (group A; n = 4) or no response or a relapse of disease (group B; n = 3) after HSCT. Immune reconstitution was analyzed every 3 months using lymphocyte immunophenotyping, alpha/beta T cell receptor (TCR) diversity analysis, and ex vivo thymic function analysis by quantification of TCR rearrangement excision circles (TRECs). RESULTS: Patients had similar characteristics at study entry, except for a lower modified Rodnan skin thickness score (P = 0.03) and a lower Health Assessment Questionnaire score (P = 0.05) in group A than in group B. The number of reinjected cells and the time to hematopoietic reconstitution were similar in both groups. The absolute numbers of CD19+ and CD20+ B cells were lower in group A than in normal controls (P < 0.05) and within the normal range in group B. Absolute numbers of T and natural killer lymphocytes were normal before HSCT. Numbers of CD3+ cells remained low thereafter. Numbers of CD8+ cells were back to normal 3 months after HSCT in both groups. B cell counts were low until 6 months after HSCT in group A and stayed in the normal range in group B. The CD3+ defect was sustained in group A, with an opposite trend and a faster CD4+ reconstitution profile in group B. The T cell repertoire was skewed before and until 1 year after HSCT, with shared expansions before and after transplant in a given individual. TREC values correlated negatively with C-reactive protein levels (r(s) = -0.41, P = 0.001) and positively with CD19+ (r(s) = 0.35, P = 0.001) and CD20+ (r(s) = 0.34, P = 0.002) lymphocyte counts. CONCLUSION: B and T lymphocyte populations remained disturbed for at least 1 year after HSCT in SSc patients, which may reflect the persistence of an underlying disease mechanism. 相似文献
37.
38.
39.
40.
Margo M.C. van Mol Esther C. Bakker Marjan D. Nijkamp Erwin J.O. Kompanje Jan Bakker Lisbeth Verharen 《Patient education and counseling》2014