全文获取类型
收费全文 | 20618篇 |
免费 | 1101篇 |
国内免费 | 112篇 |
专业分类
耳鼻咽喉 | 221篇 |
儿科学 | 410篇 |
妇产科学 | 453篇 |
基础医学 | 2642篇 |
口腔科学 | 577篇 |
临床医学 | 1606篇 |
内科学 | 5528篇 |
皮肤病学 | 514篇 |
神经病学 | 1841篇 |
特种医学 | 507篇 |
外科学 | 3190篇 |
综合类 | 102篇 |
现状与发展 | 1篇 |
一般理论 | 4篇 |
预防医学 | 1508篇 |
眼科学 | 391篇 |
药学 | 1028篇 |
中国医学 | 43篇 |
肿瘤学 | 1265篇 |
出版年
2023年 | 163篇 |
2022年 | 366篇 |
2021年 | 803篇 |
2020年 | 349篇 |
2019年 | 697篇 |
2018年 | 803篇 |
2017年 | 460篇 |
2016年 | 471篇 |
2015年 | 551篇 |
2014年 | 753篇 |
2013年 | 1055篇 |
2012年 | 1716篇 |
2011年 | 1623篇 |
2010年 | 939篇 |
2009年 | 873篇 |
2008年 | 1376篇 |
2007年 | 1405篇 |
2006年 | 1319篇 |
2005年 | 1296篇 |
2004年 | 1051篇 |
2003年 | 990篇 |
2002年 | 940篇 |
2001年 | 116篇 |
2000年 | 62篇 |
1999年 | 125篇 |
1998年 | 142篇 |
1997年 | 139篇 |
1996年 | 115篇 |
1995年 | 119篇 |
1994年 | 99篇 |
1993年 | 83篇 |
1992年 | 63篇 |
1991年 | 60篇 |
1990年 | 39篇 |
1989年 | 36篇 |
1988年 | 35篇 |
1987年 | 34篇 |
1986年 | 37篇 |
1985年 | 40篇 |
1984年 | 38篇 |
1983年 | 22篇 |
1982年 | 28篇 |
1981年 | 38篇 |
1980年 | 26篇 |
1979年 | 32篇 |
1978年 | 33篇 |
1977年 | 21篇 |
1976年 | 28篇 |
1975年 | 19篇 |
1974年 | 21篇 |
排序方式: 共有10000条查询结果,搜索用时 10 毫秒
31.
Juan M. Verdeguer M.D. Dolores Ramon M.D. Manuel Moragon M.D. Isabel Betlloch M.D. Esperanza Jorda M.D. M.D Victoria Planelles M.D. † 《Pediatric dermatology》1988,5(1):56-57
Abstract: Hydantoin is an anticonvulsant drug with several side effects. A teralogenic potential has been suggested. The fetal hydantoin syndrome is an entity that consists of a broad range of morphologic and developmental disorders in children born of epileptic mothers exposed to hydantoin during pregnancy. We treated a girl in whom onychopathy was a monosymptomatic or mild form of this syndrome. 相似文献
32.
Mehernoor F. Watcha Manuel Ramirez-Ruiz Paul F. White M. Barry Jones Richard G. Lagueruela Raghu P. Terkonda 《Journal canadien d'anesthésie》1992,39(7):649-654
Prophylactic administration of analgesics before surgery can decrease the intraoperative anaesthetic requirement and decrease pain during the early postoperative period. In a double-blind, placebo-controlled study involving 90 healthy ASA physical status I or II children undergoing bilateral myringotomy, we compared the postoperative analgesic effects of oral acetaminophen and ketorolac, when administered 30 min before induction of anaesthesia. Patients were randomized to receive saline (0.1 ml.kg-1), acetaminophen (10 mg.kg-1) or ketorolac (1 mg.kg-1) diluted in cherry syrup to a total volume of 5 ml. Anaesthesia was induced and maintained with halothane and nitrous oxide via a face mask. Postoperative pain was assessed by a blinded observer using an objective pain scale. The three study groups were similar with respect to demographic data, duration of anaesthesia and surgery, induction behaviour, oxygen saturation, incidence of postoperative emesis and, recovery times. The ketorolac group had lower postoperative pain scores and required less frequent analgesic therapy in the early postoperative period compared with the acetaminophen and placebo groups. In contrast, there were no differences in pain scores or analgesic requirements between the acetaminophen and the placebo groups. We conclude that the preoperative administration of oral ketorolac, but not acetaminophen, provided better postoperative pain control than placebo in children undergoing bilateral myringotomy. 相似文献
33.
34.
35.
Although tricyclic antidepressant are especially useful in the treatment of chronic pain conditions, most of the work about its mechanism of action has been made on acute pain tests. The present study was aimed at studying the role played by noradrenergic and opioidergic influences on the antinociceptive activity of subchronically administered clomipramine in the formalin test (a tonic pain model) in rats. Clomipramine produced antinociception after 7 days, administration (2.5 mg/kg/day), an effect equivalent to that obtained by acute morphine (5 mg/kg). The antinociceptive effect of clomipramine was inhibited by the following: nonspecific blocking of alpha1-and alpha2-adrenoceptors by phentolamine, specific blocking of alpha1-adrenoceptors by prazosin; stimulation of alpha2 receptors by clonidine; and blocking of the opioid receptors by naloxone. Blocking the alpha2-receptors with yohimbine did not antagonize the effect of clomipramine. These results suggest that clomipramine produces antinociception in this test, partly via the participation of the endogenous opioid system and partly by further activating or potentiating previously activated noradrenergic pathways which are involved in the control of pain information. 相似文献
36.
Background. Port-wine stains (PWSs) are capillary malformations that usually show progressive stasis of the vascular channels and cause slow hyperplasia of the soft and hard tissues. When these lesions involve the lower lip, macrocheilia may be developed along the time. Vascular-specific lasers are not adequate to correct these three-dimensional tissue deformities, and surgical management becomes necessary, resulting in considerable morbidity and aesthetic disturbances.
Objective. To report a case of macrocheilia secondary to PWS treated by combination of surgery and carbon dioxide laser.
Methods. A 51-year-old man with macrocheilia of the lower lip and severe functional impairment, secondary to long evolution PWS, received treatment with carbon dioxide laser vaporization and minimal surgical correction, resulting in significant improvement of the lower lip hypertrophy, good aesthetic and functional status, and preservation of the muscular function.
Conclusions. Combined carbon dioxide laser and surgery treatment may constitute a valuable alternative in treatment of macrocheilia secondary to PWS because bleeding risk is minimized and improves the preservation of muscular function and aesthetic results in relationship to conventional surgical approaches. 相似文献
Objective. To report a case of macrocheilia secondary to PWS treated by combination of surgery and carbon dioxide laser.
Methods. A 51-year-old man with macrocheilia of the lower lip and severe functional impairment, secondary to long evolution PWS, received treatment with carbon dioxide laser vaporization and minimal surgical correction, resulting in significant improvement of the lower lip hypertrophy, good aesthetic and functional status, and preservation of the muscular function.
Conclusions. Combined carbon dioxide laser and surgery treatment may constitute a valuable alternative in treatment of macrocheilia secondary to PWS because bleeding risk is minimized and improves the preservation of muscular function and aesthetic results in relationship to conventional surgical approaches. 相似文献
37.
Rogelio Leira José Castillo Francisco Martinez José Maria Prieto Manuel Noya 《Cephalalgia : an international journal of headache》1993,13(5):346-348
We measured platelet-rich plasma (PRP) serotonin in patients suffering from tension-type headache, before and after treatment with amitriptyline, comparing them with a healthy control group and patients with untreated depression. We evaluated the severity of headache and depression in each group. PRP serotonin levels were higher in patients with headache than in controls and depressed patients. We observed a fall of PRP serotonin in patients with tension-type headache to similar levels after treatment as the depressed group. This fall was correlated with the improvement of headache but not with depression scales. Our data suggest that the rise of platelet serotonin levels in tension-type headache is related to pain and not depression. 相似文献
38.
39.
40.
Ossifying fibromyxoid tumor of soft parts 总被引:1,自引:0,他引:1
A. Manuel Velasco-Pastor J. Martinez-Escribano M. del Pino Gil-Mateo E. Quecedo-Estébanez J. Miguel Fortea-Baixauli A. Aliaga-Boniche 《Journal of cutaneous pathology》1996,23(4):381-384
Ossifying fibromyxoid tumors (OFT) of soft parts are very rare neoplasms recently described by Enzinger et al. (1). They usually present as well-circumscribed, slow-growing, asymptomatic subcutaneous masses. A characteristic finding is a fibrous capsule and an incomplete peripheral shell of mature bone. Although most cases behave as benign tumors, a high rate of local recurrences have been described. We describe a 43-year-old male with a perianal subcutaneous tumor of 10 years evolution. The histopathology was compatible with OFT. Due to the subcutaneous location of OFF, both the dermatologist and dermatopathologist need to know about this rare tumor. 相似文献