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141.
142.
Aims and Objectives The significance of beaten copper appearance (BCA) on skull radiographs in children following surgery for isolated sagittal
craniosynostosis has not been studied. This study was designed to look for any correlation between BCA and symptoms suggestive
of intracranial hypertension in this group of patients.
Materials and Methods Forty-eight consecutive children, who were operated for isolated sagittal synostosis from1987 to 2000 and had postoperative
skull radiographs, were included. Patients were divided into: (a) BCA group (n = 20), consisting of children who had beaten copper appearance on skull radiographs at last follow up, and (b) Non-BCA group
(n = 28), consisting of children who did not have this finding. Records were reviewed to look for symptoms suggestive of intracranial
hypertension, such as headache, head banging, and irritability.
Results Median age at surgery was 4.8 months for BCA group and 4 months for the non-BCA group. Follow up ranged from 4 to 156 months
with a mean of 36.2 months. Total of 28.6% (n = 6) of the children with follow up radiographs done at ≤18 months of age had BCA. The incidence of BCA increased to 83.3%
in children with skull radiographs performed after 48 months of age. In 18 (90%) children, the BCA was ‘diffuse’ with 5 (25%)
children having the maximum possible score of 8. In the BCA group, 45% (n = 9) had symptoms compared to 10.7% (n = 3) in the control group (p = 0.0068).
Conclusions This study suggests a significant number of children with BCA on radiographs develop symptoms suggestive of raised ICP following
surgical treatment in infancy and prolonged follow up may be warranted in this group of patients. 相似文献
143.
144.
145.
Background
Studies have found that deaf individuals have higher rates of psychiatric disorder than those who are hearing, while at the same time encountering difficulties in accessing mental health services. These factors might increase the risk of suicide. However, the burden of suicidal behaviour in deaf people is currently unknown. 相似文献146.
Late-onset and Recurrent Neonatal Group B Streptococcal Disease Associated with Breast-milk Transmission 总被引:2,自引:0,他引:2
Michael Kotiw Gwang W. Zhang Grant Daggard Elizabeth Reiss-Levy John W. Tapsall Andrew Numa 《Pediatric and developmental pathology》2003,6(3):251-256
The purpose of the study was to determine the epidemiological relationships in three unrelated cases of neonatal late-onset Group B streptococcal (GBS) disease and maternal breast-milk infection with GBS. All deliveries were by cesarean section; case 1 was at term, and cases 2 and 3 were at 32- and 33-wk gestation, respectively. Case 1 relates to a mother with clinical mastitis and recurrent GBS infection in a 20-day-old male infant. Following antibiotic therapy and cessation of breast-feeding, the infant recovered without sequelae. Case 2 refers to a mother with clinical mastitis and the occurrence of late-onset GBS disease in 5-wk-old male twins. Despite intervention, one infant died and the second became ill. Following antibiotic therapy and cessation of breast-feeding, the surviving infant recovered without sequelae. Case 3 refers to a mother with sub-clinical mastitis and late-onset GBS infection occurring in a 6-day-old female twin. Following intervention, the infant recovered but suffered a bilateral thalamic infarction resulting in developmental delay and a severe seizure disorder. Following recovery of GBS from an inapparent mastitis and cessation of breast-feeding, the second infant remained well. Blood cultures from all affected infants and maternal breast milk were positive for GBS. Epidemiological relationships between neonatal- and maternal-derived GBS isolates were confirmed by a random amplified polymorphic DNA polymerase chain reaction assay (RAPD-PCR). This study is significant in that it has demonstrated that maternal milk (in cases of either clinical or sub-clinical mastitis) can be a potential source of infection resulting in either late-onset or recurrent neonatal GBS disease. 相似文献
147.
Ona Faye-Petersen 《Pediatric and developmental pathology》2003,6(6):599-600
148.
Recent reports of sexually transmitted infection-rate increases among men indicate the need for renewed study of male sexual risk behavior to aid development of updated and novel risk reduction interventions. Men who have childhood sexual abuse (CSA) histories consistently report frequent sexual risk behavior. The objective of this sturdy is to explore whether posttraumatic stress disorder (PTSD) and depression are moderators and/or mediators of the association between CSA and sexual risk in adult men. A cross-sectional survey study employing random digit dial recruitment was administered to men aged 18–49 years from Philadelphia County. Two bundred ninety eight men were recruited and screened for CSA history, administered items from the Posttraumatic Stress Diagnostic Scale (PDS) and Center for Epidemiologic Studies—Depression (CES-D), and asked to estimate their number of lifetime sexual partners (LSPs). Effects of sociodemographic characteristics, CSA, PTSD, and depression on the number of LSPs were modeled using Poisson regression. Results show that 197 (66%) men participated; 43 (22%) had CSA histories. CSA was significantly associated with PTSD/depression (P=.03). Four sociodemographic variables (age, race, sexual identity, and education), CSA (incidence rate ratio, IRR=1.47, P<.001), PTSD (IRR=1.19, P=.04), depression (IRR=1.29, P=.001), all 2-way interactions, and the 3-way CSA/PTSD/depression interaction (IRR=11.00, P<.001) were associated with the number of LSPs (R2=0.27). In conclusion, sexual partnership patterns unique to men with CSA histories and comorbid PTSD/depression appear to lead to substantially higher numbers of LSPs. Estimates of this relationship may have been biased toward the null by underreporting that can occur with phone surveys. Cross-sectional studies do not support causal inferences; however, the identification of a moderating and mediating influence of PTSD/depression on the relationship between CSA and sexual risk behavior is important and suggests the need for future studies with larger samples that examine trajectories for CSA, psychiatric illness, and sexual partnerships. 相似文献
149.
The patella and tibial condyle position after combined and after closing wedge high tibial osteotomy
Miklós Papp Zoltán Csernátony Sándor Kazai Zoltán Károlyi László Róde 《Knee surgery, sports traumatology, arthroscopy》2007,15(6):769-780
High tibial osteotomy changes the patella and tibial condyle position, which makes the subsequent total knee replacement technically
demanding. From 1 January 1993 to 31 December 2000, combined osteotomy [After the first osteotomy made 2 cm distally to the
joint line, a bone wedge is removed based laterally. Its tip ends at the center of the tibial condyle (half bone wedge). The
distal part of the tibia is placed into the valgus position and the half bone wedge is placed into the gap opened medially.]
was performed on 103 knees and closing wedge osteotomy was performed on 47 consecutive knees. Eighty combined (group A) and
41 closing wedge (group B) osteotomy were studied. All knees were assessed radiologically before surgery, in the 10th postoperative
week, in the 12th postoperative month and at the time of the final follow-up (in group A—66.15 months, in group B—66.61 months).
We examined the change of the femorotibial angle, of the patellar height according to the method of Insall and Salvati, of
the tibial slope angle according to the method of Bonnin, of the tibial condylar offset according to the method of Yoshida
and of the distance between the lateral tibial plateau and the top of the fibular head. In group A and B, the recurrence of
the varus deformity was not noted and valgus alignment did not increase in any case. In group-A, the Insall–Salvati ratio
remained unchanged in 65% of knees. The tibial slope angle decreased in both groups. There was correlation between the change
of the tibial condylar offset and the angle of the correction in both groups. There was correlation between the change of
the distance between the lateral tibial plateau and the top of the fibular head. After combined osteotomy, the transposition
of the tibial condyle and the decrease of the distance between the lateral tibial plateau and the top of the fibular head
was less than after closing wedge osteotomy, although the average angle of correction was more after combined osteotomy (11.835°),
than after closing wedge osteotomy (9.465°). Theoretically, the recurrence of the varus deformity, the increase of the valgus
alignment and (in majority of cases) the shortening of the patellar tendon do not compromise the likelihood of successful
conversion to the subsequent total knee replacement, either after combined or after closing wedge osteotomy. The combined
osteotomy does not lead to considerable transposition of the tibial condyle and to considerable lateral tibial bone loss;
therefore, theoretically, the combined osteotomy does not impair the subsequent total knee replacement. 相似文献
150.