全文获取类型
收费全文 | 149239篇 |
免费 | 31160篇 |
国内免费 | 2388篇 |
专业分类
耳鼻咽喉 | 5158篇 |
儿科学 | 5332篇 |
妇产科学 | 2371篇 |
基础医学 | 2911篇 |
口腔科学 | 1461篇 |
临床医学 | 26528篇 |
内科学 | 46853篇 |
皮肤病学 | 7411篇 |
神经病学 | 14673篇 |
特种医学 | 6305篇 |
外科学 | 40740篇 |
综合类 | 228篇 |
现状与发展 | 72篇 |
预防医学 | 6938篇 |
眼科学 | 3328篇 |
药学 | 867篇 |
中国医学 | 8篇 |
肿瘤学 | 11603篇 |
出版年
2024年 | 684篇 |
2023年 | 4780篇 |
2022年 | 1170篇 |
2021年 | 3042篇 |
2020年 | 5999篇 |
2019年 | 2117篇 |
2018年 | 7336篇 |
2017年 | 7297篇 |
2016年 | 8371篇 |
2015年 | 8358篇 |
2014年 | 15420篇 |
2013年 | 15530篇 |
2012年 | 5332篇 |
2011年 | 5346篇 |
2010年 | 10269篇 |
2009年 | 14169篇 |
2008年 | 5664篇 |
2007年 | 3883篇 |
2006年 | 6363篇 |
2005年 | 3659篇 |
2004年 | 2916篇 |
2003年 | 1908篇 |
2002年 | 1991篇 |
2001年 | 3778篇 |
2000年 | 3002篇 |
1999年 | 3194篇 |
1998年 | 3629篇 |
1997年 | 3450篇 |
1996年 | 3354篇 |
1995年 | 3203篇 |
1994年 | 1933篇 |
1993年 | 1562篇 |
1992年 | 1378篇 |
1991年 | 1410篇 |
1990年 | 1056篇 |
1989年 | 1175篇 |
1988年 | 1019篇 |
1987年 | 848篇 |
1986年 | 882篇 |
1985年 | 715篇 |
1984年 | 548篇 |
1983年 | 519篇 |
1982年 | 512篇 |
1981年 | 400篇 |
1980年 | 359篇 |
1979年 | 307篇 |
1978年 | 328篇 |
1977年 | 399篇 |
1975年 | 282篇 |
1972年 | 303篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
111.
112.
113.
S. MD. Iqbal A. K. Garg C. M. Kalaiah 《Indian journal of otolaryngology and head and neck surgery》1987,39(1):38-39
A case of Goldenhar’s Syndrome in a 10 year old girl is reported. The unusual features are the absence of epibulbar dermoid which is one of the major hallmarks of the Syndrome and the presence of an associated Cyanotic Heart disease. 相似文献
114.
Central Sensitization Theory of Migraine: Clinical Implications 总被引:4,自引:2,他引:2
The clinical science of migraine headache continues to evolve. Theories of the pathophysiology of migraine have progressed from the early vascular basis of migraine to more complex current theories that emphasize the centrality of neuronal dysfunction. The most recently articulated theory of migraine is the central sensitization hypothesis, which proposes that altered processing of sensory input in the brainstem, principally the trigeminal nucleus caudalis, could account for many of the temporal and symptomatic features of migraine, as well as its poor response to triptan therapy when such treatment is initiated hours after the onset of pain. Both preclinical and clinical data support the central sensitization theory. A critical clinical implication of this theory is that drugs that are capable of either aborting or arresting the process of central sensitization, most prominently dihydroergotamine, may have a unique role in the treatment of migraine. An additional, and highly practical, implication is based upon the finding that cutaneous allodynia—pain arising from innocuous stimulation of the skin, as in hair brushing or the application of cosmetics—is an easily identifiable marker of central sensitization. Thus, the presence or absence of cutaneous allodynia can be integrated into the routine clinical assessment of migraine and utilized as a determinant of treatment. Future basic and clinical research on central sensitization is likely to be of ongoing importance to the field. 相似文献
115.
An Analysis of the Buy-Vs-Lease Decision 总被引:1,自引:0,他引:1
116.
Theodore Berk MD Robert F. Crochelt BA Dr. Steven R. Peikin MD 《Digestive diseases and sciences》1986,31(5):502-505
Obese Zucker rats are less responsive than their lean littermates to the effects of cholecystokinin-octapeptide on satiety and pancreatic growth and exocrine function. We hypothesized that the hyperphagia observed in obese Zucker rats may be caused by a decreased pyloric contractile response to cholecystokinin, resulting in an increased rate of gastric emptying, decreased postprandial gastric distention, and thus decreased satiety. Pyloric muscle strips from six obese Zucker rats and six lean littermates were mounted in separate tissue baths and isometric contraction was measured in response to acetylcholine and cholecystokinin-octapeptide. The dose-response curves for acetylcholine-and cholecystokinin-octapeptide-stimulated pyloric muscle contraction were similar for both the obese and the lean rats. (For cholecystokinin, D50 obese=4.0±0.6 nM, D50 lean=3.4±0.2 nM;P=0.16). We conclude that the decreased satiety response to cholecystokinin-octapeptide observed in obese Zucker rats is not secondary to a decreased pyloric responsiveness to cholecystokinin.This work was supported by NIH grant AM28303-03. 相似文献
117.
118.
119.
Chemoprevention refers to suppression or reversal of the carcinogenic process using pharmacologic or nutritional agents. Colorectal
carcinogenesis is a protracted, multistep process that offers opportunities for prevention. Aspirin and selective cyclooxygenase-2
inhibitors (coxibs) have been evaluated for the prevention of sporadic adenoma recurrence. Aspirin was shown to reduce adenoma
recurrence rates in patients with prior colorectal neoplasms; however, the optimal dosage remains unclear. Recent studies
of coxibs indicate that these agents are effective in reducing sporadic adenoma recurrence, but chronic use can result in
serious cardiovascular toxicity. These data underscore the need for chemopreventive agents with acceptable risk-to-benefit
ratios. In this regard, nitric-oxide-releasing aspirin shows chemopreventive efficacy in preclinical models and holds promise
for reduced toxicity in humans. Furthermore, ongoing chemoprevention trials are evaluating nutritional supplements, such as
folic acid and selenium, and results are eagerly awaited. 相似文献
120.