全文获取类型
收费全文 | 22714篇 |
免费 | 1748篇 |
国内免费 | 33篇 |
专业分类
耳鼻咽喉 | 195篇 |
儿科学 | 774篇 |
妇产科学 | 621篇 |
基础医学 | 2804篇 |
口腔科学 | 397篇 |
临床医学 | 2764篇 |
内科学 | 4041篇 |
皮肤病学 | 395篇 |
神经病学 | 2094篇 |
特种医学 | 701篇 |
外科学 | 3292篇 |
综合类 | 362篇 |
一般理论 | 38篇 |
预防医学 | 2368篇 |
眼科学 | 546篇 |
药学 | 1598篇 |
3篇 | |
中国医学 | 12篇 |
肿瘤学 | 1490篇 |
出版年
2022年 | 156篇 |
2021年 | 373篇 |
2020年 | 221篇 |
2019年 | 409篇 |
2018年 | 466篇 |
2017年 | 335篇 |
2016年 | 376篇 |
2015年 | 397篇 |
2014年 | 591篇 |
2013年 | 898篇 |
2012年 | 1328篇 |
2011年 | 1443篇 |
2010年 | 750篇 |
2009年 | 679篇 |
2008年 | 1159篇 |
2007年 | 1207篇 |
2006年 | 1205篇 |
2005年 | 1103篇 |
2004年 | 1043篇 |
2003年 | 1024篇 |
2002年 | 903篇 |
2001年 | 511篇 |
2000年 | 542篇 |
1999年 | 461篇 |
1998年 | 250篇 |
1997年 | 173篇 |
1996年 | 186篇 |
1995年 | 182篇 |
1994年 | 142篇 |
1993年 | 161篇 |
1992年 | 420篇 |
1991年 | 367篇 |
1990年 | 379篇 |
1989年 | 349篇 |
1988年 | 359篇 |
1987年 | 326篇 |
1986年 | 307篇 |
1985年 | 333篇 |
1984年 | 260篇 |
1983年 | 219篇 |
1982年 | 149篇 |
1981年 | 126篇 |
1980年 | 121篇 |
1979年 | 237篇 |
1978年 | 172篇 |
1977年 | 124篇 |
1976年 | 116篇 |
1974年 | 119篇 |
1973年 | 128篇 |
1970年 | 116篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Julia H. Vermylen Gordon J. Wood Elaine R. Cohen Jeffrey H. Barsuk William C. McGaghie Diane B. Wayne 《Journal of pain and symptom management》2019,57(3):682-687
Introduction
Physician communication impacts patient outcomes. However, communication skills, especially around difficult conversations, remain suboptimal, and there is no clear way to determine the validity of entrustment decisions. The aims of this study were to 1) describe the development of a simulation-based mastery learning (SBML) curriculum for breaking bad news (BBN) conversation skills and 2) set a defensible minimum passing standard (MPS) to ensure uniform skill acquisition among learners.Innovation
An SBML BBN curriculum was developed for fourth-year medical students. An assessment tool was created to evaluate the acquisition of skills involved in a BBN conversation. Pilot testing was completed to confirm improvement in skill acquisition and set the MPS.Outcomes
A BBN assessment tool containing a 15-item checklist and six scaled items was developed. Students' checklist performance improved significantly at post-test compared to baseline (mean 65.33%, SD = 12.09% vs mean 88.67%, SD = 9.45%, P < 0.001). Students were also significantly more likely to have at least a score of 4 (on a five-point scale) for the six scaled questions at post-test. The MPS was set at 80%, requiring a score of 12 items on the checklist and at least 4 of 5 for each scaled item. Using the MPS, 30% of students would require additional training after post-testing.Comments
We developed a SBML curriculum with a comprehensive assessment of BBN skills and a defensible competency standard. Future efforts will expand the mastery model to larger cohorts and assess the impact of rigorous education on patient care outcomes. 相似文献2.
3.
Recurrent erosion 总被引:1,自引:0,他引:1
4.
Measurement of cerebral monoamine oxidase B activity using L-[11C]deprenyl and dynamic positron emission tomography 总被引:3,自引:0,他引:3
A A Lammertsma C J Bench G W Price J E Cremer S K Luthra D Turton N D Wood R S Frackowiak 《Journal of cerebral blood flow and metabolism》1991,11(4):545-556
A tracer kinetic procedure was developed for the measurement of monoamine oxidase type B (MAO-B) activity using L-[11C]deprenyl and positron emission tomography (PET). The kinetic model consisted of two tissue compartments with irreversible binding to the second compartment (three rate constants). In addition, a blood volume component was included. Special attention was given to the accurate measurement of the plasma and whole blood input functions. The method was applied to the measurement of the dose-response curve of a reversible MAO-B inhibitor (Ro 19-6327). From the results, it followed that the rate constant for irreversible binding (k3) appeared to be a better index of MAO-B activity than the net influx constant Ki. Furthermore, regional analysis demonstrated that Ki, but not k3, was flow dependent. This implies that full kinetic analysis is required for an accurate assessment of MAO-B activity. 相似文献
5.
A cohort of 1163 pregnant women in two small towns in South Wales, UK, was identified and followed until the children born to them were five years of age. Growth in these children is described and a number of determinants identified. Social-class differences were very small at birth but differences in height became clear by the age of two years and in head circumference before this. In height the differences were largely accounted for by greater growth in social class I, but there was a gradient in head circumference throughout all the social classes. The social class effects gradually increased as the children became older. Parity of the mothers had a small effect on size at birth but age of the mother had no effect once parity was allowed for. Data on illnesses in the children were collected but no effect on growth could be detected. By far the most important determinant of growth which could be controlled is maternal smoking. About 40% of the women smoked, about 17% heavily (15 or more cigarettes per day) and the prevalence of smoking altered little during pregnancy. There was a graded effect of smoking on growth up to a 9% deficit in birth-weight, a 2% deficit in length at birth and a 1.5% deficit in head circumference in the babies born to the mothers who smoked most heavily (25 or more cigarettes per day) compared with non-smokers. There effects decreased with age but there were still residual effects at age five years. 相似文献
6.
7.
8.
Activation of the ras oncogene is associated with overproduction of the normal gene product (p21). Ninety one paraffin-embedded specimens were used to map the distribution of the normal form of p21 in normal, inflamed, cirrhotic and carcinomatous liver parenchyma. Monoclonal antibodies (Mo-RAP) were raised against the normal form of the ras-oncogene product and histological sections were stained by the peroxidase-antiperoxidase technique. Normal, inflamed and cirrhotic liver showed either minimal or moderate cytoplasmic staining. By contrast primary (n = 13) and secondary (n = 41) liver carcinomas exhibited intense staining. The differential pattern observed in p21 distribution could have useful clinical applications. 相似文献
9.
S Lori Brown Roselie A Bright Diane E Dwyer Betsy Foxman 《Journal of human lactation》2005,21(2):169-174
Breast pumps are medical devices used to express milk and maintain the milk supply. The purpose of this study was to characterize adverse events reported to the United States Food and Drug Administration (FDA) on breast pumps. Thirty-seven adverse event reports on breast pumps were identified from the Manufacturer and User Facility Device Experience database between 1992 and 2003. Four additional reports were found in the Device Experience Network database from 1992 to 1996. The most commonly reported adverse events for electric breast pumps were pain, soreness, or discomfort; the need for medical intervention; and breast tissue damage. Most frequently reported problems for manual breast pumps were breast tissue damage and infection. Contamination of breast milk during pumping was also reported. Breast pump adverse events are likely underreported to the FDA. Reporting adverse events is important for improving the design and manufacture of breast pumps and subsequently decreasing adverse events. 相似文献
10.