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排序方式: 共有574条查询结果,搜索用时 15 毫秒
61.
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A Kalovidouris D Voros A Gouliamos L Vlachos C Papavasiliou 《Gastrointestinal radiology》1992,17(4):353-356
Sixteen percent of hydatid cysts in the liver in 185 patients examined by computed tomography (CT) showed daughter cysts located exterior to the fibrinous membrane of the main hydatid cysts. We call these extracapsular or satellite cysts. Extracapsular cysts have the same appearance as endogenous daughter cysts. Preoperative demonstration of these cysts is useful for planning an appropriate surgical treatment and reduction of the recurrence rate. 相似文献
63.
Ensuring patient safety in the management of medicines requires the efficient collection, administration, analysis and distribution of huge amounts of data from different sources. This requires the development of generic methods and tools for tasks such as: (1) data mining and semantics-based inference; (2) integration of heterogeneous scientific information databases relating to drugs and diseases; (3) terminology and coding issues; (4) adverse drug events and signal detection; and (5) networking and security. Collaborative research and development will be required to develop coordinated health care information services. Easy access to high-quality information will provide better health care and increased cost efficiency. 相似文献
64.
Vlachos K Siafakas N Karameris A Athanasas G Theodoropoulos G Parassi E Peros G Papadopoulos J Hakim N 《International surgery》2006,91(6):320-325
The Fas/FasL system plays an important role in the regulation of tumor apoptosis. This study examined the correlation between the expression levels of Fas and WAF1 with the clinicopathological characteristics of esophageal squamous cell carcinoma (SCC) tumors. Paraffin-embedded sections from 19 surgically resected primary esophageal squamous cell carcinomas were examined by immunohistochemistry. At low expression levels (5% to 24%), a 4-fold higher expression of Fas relative to WAF1 expression was observed. High expression levels (50% to 74%) of Fas were not recorded, whereas such levels of expression for WAF1 were retained in a proportion of cells > 20%. Proteins WAF1 and Fas were both expressed in all lesions of SCCs. Lesions showing high expression levels of WAF1 have a high degree of differentiation, but a sample that expresses WAF1 and belongs to the morphology I category probably has a medium degree of differentiation. 相似文献
65.
Sotiropoulou M Haidopoulos D Vlachos G Pilalis A Rodolakis A Diakomanolis E 《Archives of gynecology and obstetrics》2005,271(3):265-267
Case report We report the case of a 74-year old woman who presented with an ulcerated mass of the vagina. Histology of the tumor showed malignant mixed mullerian tumor (MMMT) with squamous and spindle cell stromal components, associated with high-grade vaginal intraepithelial neoplasia (VaIN 3). Immunohistochemical study of the neoplasm revealed that the malignant stromal tumor was a high-grade leiomyosarcoma. Despite the multimodal therapeutic approach, the patient died within 11 months.Conclusion The vagina is a rare site of presentation of primary MMMTs and the present case is the second one immunohistochemically confirmed. 相似文献
66.
Kalantaridou SN Naka KK Papanikolaou E Kazakos N Kravariti M Calis KA Paraskevaidis EA Sideris DA Tsatsoulis A Chrousos GP Michalis LK 《The Journal of clinical endocrinology and metabolism》2004,89(8):3907-3913
Normal menopause is associated with vascular endothelial dysfunction, an early stage of atherosclerosis. The effect of premature ovarian failure (or premature menopause) on endothelial function in young women is unknown. Endothelial function was assessed in 18 women with premature ovarian failure before and after 6 months of hormone therapy and was compared with the endothelial function of 20 age- and body mass index-matched premenopausal women. Brachial artery diameter was measured both during hyperemia (an index of endothelium-dependent vasodilation) and in response to glyceryl trinitrate (an index of endothelium-independent vaso-dilation). Flow-mediated dilation was significantly lower in women with premature ovarian failure at baseline (increase in brachial artery diameter during hyperemia by 3.06 +/- 4.33%) than in control women (increase by 8.84 +/- 2.15%; P < 0.0005). Glyceryl trinitrate-induced vasodilation did not differ between the groups. After hormone therapy for 6 months, flow-mediated dilation was improved in women with premature ovarian failure, increasing by more than 2-fold (7.41 +/- 3.86%; P < 0.005 compared with pretreatment) and reaching normal values (P not significant compared with control women). Glyceryl trinitrate-induced vasodilation did not change after treatment in women with premature ovarian failure. Young women with premature ovarian failure have significant vascular endothelial dysfunction. Early onset of endothelial dysfunction associated with sex steroid deficiency may contribute to the increased risk of cardiovascular disease and mortality in young women with premature ovarian failure. Hormone therapy restores endothelial function within 6 months of treatment. 相似文献
67.
68.
Falidas E Vlachos K Mathioulakis S Archontovasilis F Villias C 《World journal of emergency surgery : WJES》2011,6(1):8
Multiple diverticulosis of jejunum represents an uncommon pathology of the small bowel. The disease is usually asymptomatic
and must be taken into consideration in cases of unexplained malabsorption, anemia, chronic abdominal pain or discomfort.
Related complications such as diverticulitis, perforation, bleeding or intestinal obstruction appear in 10-30% of the patients
increasing morbidity and mortality rates. We herein report a case of a 55 year-old man presented at the emergency department
with acute abdominal pain, vomiting and fever. Preoperative radiological examination followed by laparotomy revealed multiple
giant jejunal diverticula causing intestinal obstruction. We also review the literature for this uncommon disease. 相似文献
69.
70.
Blood–brain barrier opening using focused ultrasound and microbubbles has been experimentally established as a noninvasive and localized brain drug delivery technique. In this study, the permeability of the opening is assessed in the murine hippocampus after the application of focused ultrasound at three different acoustic pressures and microbubble sizes. Using dynamic contrast‐enhanced MRI, the transfer rates were estimated, yielding permeability maps and quantitative Ktrans values for a predefined region of interest. The volume of blood–brain barrier opening according to the Ktrans maps was proportional to both the pressure and the microbubble diameter. A Ktrans plateau of ~0.05 min?1 was reached at higher pressures (0.45 and 0.60 MPa) for the larger sized bubbles (4–5 and 6–8 μm), which was on the same order as the Ktrans of the epicranial muscle (no barrier). Smaller bubbles (1–2 μm) yielded significantly lower permeability values. A small percentage (7.5%) of mice showed signs of damage under histological examination, but no correlation with permeability was established. The assessment of the blood–brain barrier permeability properties and their dependence on both the pressure and the microbubble diameter suggests that Ktrans maps may constitute an in vivo tool for the quantification of the efficacy of the focused ultrasound‐induced blood–brain barrier opening. Magn Reson Med, 2011. © 2011 Wiley‐Liss, Inc. 相似文献