High resolution MR imaging of the bilateral hips with dual phased-array coil

We applied dual-flex coils in a phased-array configuration to obtain high resolution MR images of the bilateral hips and compared the image quality with non-phased-array imaging. Multiple fast spin-echo images of both hips were obtained in a single acquisition. Two consecutive acquisitions with and without phased-array capability were performed in 22 hips and a fluid-filled phantom. The signal-to-noise ratio (S/N) enhancement values were calculated. Subjective image analysis was also obtained from three independent reviewers. High quality MR images were obtained using dual-array coils with a S/N enhancement value of 1.40 for a phantom and 1.83 to 2.22 for subject hips. On subjective analysis, the dual array enhanced delineation of the acetabular labrum, articular cartilage, and retained fluid. The dual array may be of diagnostic value with a higher S/N enhancement and subjective superiority of the images obtained.     

Morphological Changes Induced in the Central Nervous System of Rats by Steroid Drug

Abstract: Wistar strain male rats (body weight 180 g) were given 0.5 mg β-methasone per kilogram of body weight orally each day for 180 days. Histopathologically, remarkable changes occurred only in the hypothalamus and thalamus. The mitochondria showed vacuolar degeneration not only in the nerve cells but also in the nerve fibers and glia cells, and the Golgi apparatus was well developed in the nerve cells. By the freeze fracture method, the intramembranous large globular molecules of mitochondria and nuclei of the nerve cells decreased in number. The steroid affects mainly the hypothalamus and thalamus. This might have a close relation to steroid psychosis.     

Neuro-Behçet's disease showing severe atrophy of the cerebrum

Summary A 38-year-old female died 6 years after the onset of what was, clinically and histopathologically, consistent with Neuro-Behçet's disease. Pathologically the cerebrum showed severe atrophy. The main changes were observed in the grey and white matter, the diencephalon and the basal ganglia by light microscopy. All these changes originated in softenings around blood vessels, especially small vessels or capillaries. These foci fused together to form large regions of softening. Glial or mesenchymal reactions were minimal. In the white matter there was slight perivascular-infiltration, mainly consisting of lymphocytes. In view of these findings, it is suggested that these changes were caused by an allergic vasculitis. The present case of Neuro-Behçet's disease is the first one showing general atrophy of the cerebrum. It is very important in relation to demyelinating encephalitis.