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91.
92.
Tomoko Noma Mai Kabayama Yasuyuki Gondo Saori Yasumoto Yukie Masui Ken Sugimoto Hiroshi Akasaka Kayo Godai Atsuko Higuchi Yuya Akagi Yoichi Takami Yasushi Takeya Koichi Yamamoto Kazunori Ikebe Yasumichi Arai Tatsuro Ishizaki Hiromi Rakugi Kei Kamide 《Geriatrics & Gerontology International》2020,20(7):720-726
93.
94.
Otani T Yoshimatsu K Yokomizo H Fujimoto T Umehara A Matsumoto A Osawa G Itagaki H Yano Y Ogawa K 《Hepato-gastroenterology》2012,59(114):395-399
Background/Aims: To investigate differences in clinicopathological features between proximal and distal pT3 colon cancers and to determine whether the depth of the cancer invasion beyond the muscularis propria (DBM) serves as an objective indicator of the depth of tumor invasion in proximal colon cancer and in distal colon cancer. Methodology: A total of 207 patients who underwent surgery for proximal and distal pT3 colon cancer between 1996 and 2001 were included in the analysis. Results: No differences were noted between proximal and distal cancers in lymph node metastasis, distant metastasis, lymphatic/venous invasion, histological type and curability of surgical resection, although proximal cancer patients were significantly older. High-grade malignancy appeared to be more commonly noted in the proximal colon cancer cases but there was no significant difference in prognosis between proximal and distal cancer patients. Conclusions: Regarding the correlation between DBM and prognosis, there was a significant decrease in the 5-year survival rate in patients with proximal lesions of DBM 3000μm or more, and patients with distal lesions of DBM 5000μm or more. DBM is thus an objective indicator of depth of tumor invasion for both proximal and distal lesions, a prognostic factor and a guide to determining whether postoperative adjuvant chemotherapy is indicated for pT3 colon cancer cases. 相似文献
95.
Minobu Shichiji Yasushi Ito Keiko Shimojima Hidetsugu Nakamu Hirokazu Oguni Makiko Osawa Toshiyuki Yamamoto 《American journal of medical genetics. Part A》2013,161(4):850-855
The 2q23.1 deletion syndrome has been recently recognized as a neurodevelopmental disorder associated with intellectual disability, epilepsy, and autism spectrum disorder. Recently, methyl‐CpG‐binding domain 5 gene (MBD5), located in the 2q23.1 region, has been considered as a single causative gene of this syndrome. We report on a female patient with a de novo reciprocal translocation between chromosomes 2 and 5. Chromosomal microarray testing revealed a cryptic 896 kb deletion that included MBD5. Although clinical manifestations of this patient are compatible with those of patients with 2q23.1 deletion syndrome, a focal pachygyria revealed by brain magnetic resonance imaging has never been observed in the previously reported cases. Obesity caused by hyperphagia was observed in our patient and 28% of the previously reported patients with the 2q23.1 deletion syndrome. For better medical management, appropriate dietary guidance against hyperphagia should be given to the patients' family. © 2013 Wiley Periodicals, Inc. 相似文献
96.
Masanori Aihara Hiroya Fujimaki Ryosuke Shintoku Tadashi Osawa Ken Asakura Mizuho Miyazaki Tetsuyoshi Horiuchi Junpei Nitta 《Acta neurochirurgica》2013,155(4):607-609
Background
Superficial temporal artery-to-middle cerebral artery (STA-MCA) anastomosis is a common procedure for neurosurgeons. The surgery necessarily requires accurate and speedy manipulation of microscope, for which a specific training is needed. Unexpected bypass occlusion sometimes happen during surgery.Objective
Generally, conventional interrupted or continuous suture has been used for vascular anastomosis, despite various ideas have been attempted in the other surgery fields. We propose a horizontal mattress suture technique for intracranial microvascular bypass surgery. This is the first report ever published on intracranial vascular anastomosis.Methods
We had four patients of STA-MCA bypass surgery with “mattress anastomosis” from March to May of 2012.Results
During the procedure, there was no bypass occlusion and good patency was confirmed in all cases.Conclusion
Intimae of the recipient and the donor blood vessel contact each other precisely with this technique. Although a long-term assessment of patency is needed, it is useful for the intracranial bypass surgery. 相似文献97.
98.
Terai T Sugimoto M Uozaki H Kitagawa T Kinoshita M Baba S Yamada T Osawa S Sugimoto K 《World journal of gastroenterology : WJG》2012,18(17):2140-2144
Extranodal natural killer (NK)/T-cell lymphoma, nasal type, exhibits aggressive tumor behavior and carries a poor prognosis. Recently, lymphomatoid gastropathy with NK/T cell infiltration into gastric mucosa has been recognized as a pseudo-malignant disease which regresses without treatment. Because the conventional immunohistochemical criteria of lymphomatoid gastropathy is similar to that of extranodal NK/T-cell lymphoma nasal type, it is difficult to distinguish between the two conditions by histopathological evaluation only. Here, we report a rare case of lymphomatoid gastropathy in a 57-year-old female. Gastroendoscopy on routine check-up revealed elevated reddish lesions < 1 cm in diameter in the gastric fornix and body. Although repeat endoscopies at 1 and 6 mo later revealed no gastric lesions at any locations without any treatments, at 12 mo later gastric lymphomatoid lesions recurred at gastric fornix and body. Histological examination of endoscopic biopsy specimens at 12 mo showed atypical NK cell infiltration with CD3+, CD4-, CD5-, CD7+, CD8-, CD20-, CD30-, CD56+, CD79a- and T-cell-restricted intracellular antigen-1+ into gastric mucosa. After treatment for Helicobacter pylori (H. pylori) eradication, the lesions disappeared in all locations of the gastric fornix and body over the subsequent 12 mo. Here, we report a case of H. pylori-positive lymphomatoid gastropathy with massive NK-cell proliferation, and also review the literature concerning newly identified lymphomatoid gastropathy based on comparison of extra nodal NK/T-cell lymphoma nasal type. In any case, these lesions are evaluated with biopsy specimens, the possibility of this benign entity should be considered, and excessive treatment should be carefully avoided. Close follow-up for this case of lymphomatoid gastropathy is necessary to exclude any underlying malignancy. 相似文献
99.
100.
Hideki Osawa Junichi Hasegawa Kazuma Yamakawa Nobuki Matsunami Shoki Mikata Junzo Shimizu Yong Kook Kim Hirotaka Morishima Masaki Hirota Yoshihito Souma Ho Min Kim Genta Sawada Riichiro Nezu 《Surgery today》2013,43(7):745-750