全文获取类型
收费全文 | 32995篇 |
免费 | 4113篇 |
国内免费 | 366篇 |
专业分类
耳鼻咽喉 | 797篇 |
儿科学 | 856篇 |
妇产科学 | 603篇 |
基础医学 | 3009篇 |
口腔科学 | 945篇 |
临床医学 | 3229篇 |
内科学 | 8225篇 |
皮肤病学 | 943篇 |
神经病学 | 3200篇 |
特种医学 | 1282篇 |
外科学 | 6645篇 |
综合类 | 169篇 |
现状与发展 | 2篇 |
一般理论 | 1篇 |
预防医学 | 1376篇 |
眼科学 | 702篇 |
药学 | 1759篇 |
中国医学 | 28篇 |
肿瘤学 | 3703篇 |
出版年
2023年 | 621篇 |
2022年 | 338篇 |
2021年 | 702篇 |
2020年 | 956篇 |
2019年 | 506篇 |
2018年 | 1091篇 |
2017年 | 926篇 |
2016年 | 1141篇 |
2015年 | 1117篇 |
2014年 | 1455篇 |
2013年 | 1682篇 |
2012年 | 1279篇 |
2011年 | 1323篇 |
2010年 | 1240篇 |
2009年 | 1356篇 |
2008年 | 1217篇 |
2007年 | 1247篇 |
2006年 | 1275篇 |
2005年 | 1193篇 |
2004年 | 1082篇 |
2003年 | 998篇 |
2002年 | 1034篇 |
2001年 | 1108篇 |
2000年 | 1014篇 |
1999年 | 1019篇 |
1998年 | 546篇 |
1997年 | 498篇 |
1996年 | 585篇 |
1995年 | 443篇 |
1994年 | 333篇 |
1993年 | 272篇 |
1992年 | 658篇 |
1991年 | 618篇 |
1990年 | 575篇 |
1989年 | 582篇 |
1988年 | 529篇 |
1987年 | 508篇 |
1986年 | 461篇 |
1985年 | 478篇 |
1984年 | 365篇 |
1983年 | 259篇 |
1982年 | 186篇 |
1981年 | 148篇 |
1979年 | 243篇 |
1978年 | 187篇 |
1977年 | 183篇 |
1975年 | 153篇 |
1974年 | 150篇 |
1971年 | 154篇 |
1970年 | 148篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
101.
Jocelyn M. Cottrell BS Marjolein C. H. van der Meulen PhD Joseph M. Lane MD Elizabeth R. Myers PhD 《HSS journal》2006,2(1):12-18
The clinical goal of spinal fusion is to reduce motion and the associated pain. Therefore, measuring motion under loading
is critical. The purpose of this study was to validate four-point bending as a means to mechanically evaluate simulated fusions
in dog and rabbit spines. We hypothesized that this method would be more sensitive than manual palpation and would be able
to distinguish unilateral vs bilateral fusion. Spines from four mixed breed dogs and four New Zealand white rabbits were used
to simulate posterolateral fusion with polymethyl methacrylate as the fusion mass. We performed manual palpation and nondestructive
mechanical testing in four-point bending in four planes of motion: flexion, extension, and right and left bending. This testing
protocol was used for each specimen in three fusion modes: intact, unilateral, and bilateral fusion. Under manual palpation,
all intact spines were rated as not fused, and all unilateral and bilateral simulated fusions were rated as fused. In four-point
bending, dog spines were significantly stiffer after unilateral fusion compared with intact in all directions. Additionally,
rabbit spines were stiffer in flexion and left bending after unilateral fusion. All specimens exhibited significant differences
between intact and bilateral fusion except the rabbit in extension. For unilateral vs bilateral fusion, significant differences
were present for right bending in the dog model and for flexion in the rabbit. Unilateral fusion can provide enough stability
to constitute a fused grade by manual palpation but may not provide structural stiffness comparable to bilateral fusion. 相似文献
102.
103.
T Yamagami S Iida T Kato T Hirota T Nishimura 《Journal of Medical Imaging and Radiation Oncology》2006,50(1):75-78
We present a patient with gastric varices complicating portal hypertension caused by liver cirrhosis related to hepatitis C virus. The patient underwent balloon‐occluded retrograde transvenous obliteration. The gastric varices almost completely disappeared, without any sclerotic agent being used, after iatrogenic injury of the gastrorenal shunt at the time of the interventional procedure. 相似文献
104.
Senichiro Kikuchi Kazuhiko Iwata Yasunori Onishi Fumio Kubota Koichi Nisijima Hideaki Tamai Yuiko Koizumi Eiju Watanabe Satoshi Kato 《Psychiatry Research: Neuroimaging》2007,156(3):199-208
We conducted a noninvasive near-infrared spectroscopy (NIRS) study using the game of rock, paper, scissors (RPS) as a simple neurocognitive task for the prefrontal cortex (PFC) in 15 healthy volunteers. We employed an opposite “to lose” RPS task coupled with a normal “to win” RPS task, since the former requires inhibition of behavior, one of the most important functions of the prefrontal cortex. During the NIRS examination, subjects had to present one of the three RPS hands in response to hands displayed randomly on a computer screen every 1.5 s, and were required to show hands that lose to the computer, or that beat the computer. We measured the relative concentrations of oxyhemoglobin (oxy-Hb) using the prefrontal probes of the NIRS system during the tasks. The increases in oxy-Hb during the “to win” RPS task were small, but were quite large and laterally dominant during the “to lose” RPS task. The difference between the two tasks might have been due to the participants’ cognitive conflict with losing on the RPS. We conclude that losing is better than winning on the RPS as a sensitive indicator in the NIRS examination of PFC. 相似文献
105.
Cytochrome P450IIE1 genetic polymorphisms, racial variation, and lung cancer risk. 总被引:10,自引:0,他引:10
S Kato P G Shields N E Caporaso R N Hoover B F Trump H Sugimura A Weston C C Harris 《Cancer research》1992,52(23):6712-6715
106.
107.
Reduction of scar formation in full-thickness wounds with topical celecoxib treatment 总被引:4,自引:0,他引:4
Traci A. Wilgus PhD ; Yael Vodovotz PhD ; Elena Vittadini PhD ; Elizabeth A. Clubbs BS ; Tatiana M. Oberyszyn PhD 《Wound repair and regeneration》2003,11(1):25-34
Adult wound repair occurs with an initial inflammatory response, reepithelialization, and the formation of a permanent scar. Although the inflammatory phase is often considered a necessity for successful adult wound healing, fetal healing studies have shown the ability to regenerate skin and to heal wounds in a scarless manner in the absence of inflammation. The cyclooxygenase-2 (COX-2) enzyme, a known mediator of inflammation, has been shown to contribute to a variety of inflammatory conditions and to the development of cancer in many organs. To examine the role of COX-2 in the wound healing process, incisional wounds were treated topically with the anti-inflammatory COX-2 inhibitor celecoxib. Acutely, celecoxib inhibited several parameters of inflammation in the wound site. This decrease in the early inflammatory phase of wound healing had a significant effect on later events in the wound healing process, namely a reduction in scar tissue formation, without disrupting reepithelialization or decreasing tensile strength. Our data suggest that in the absence of infection, adult wound healing is able to commence with decreased inflammation and that anti-inflammatory drugs may be used to improve the outcome of the repair process in the skin by limiting scar formation. 相似文献
108.
LY Chow MRCPsych D Chung MRCPsych V Leung MB BS TF Leung MB ChB CM Leung MRCPsych 《International journal of clinical practice》1997,51(5):330-331
Akathisia as a side-effect of metoclopramide has received increasing attention in consultation-liaison psychiatry in recent years. A case of metoclopramide-induced akathisia resulting in a suicide attempt is reported in order to highlight the suffering of such patients and the factors that lead to misdiagnosis. 相似文献
109.
110.
Hitoshi Taguchi Koh Yamada Hideo Matsumoto Akira Kato Toshihiro Imanishi Koh Shingu 《Journal of anesthesia》1997,11(3):173-178
Purpose Several case reports indicate critical respiratory complications in relation to the double-lumen endobronchial tube (DLT).
A prospective survey for the airway problems in using the DLT is presented.
Methods One hundred adult patients undergoing thoracotomy for lung cancer were investigated. Tube malposition and airway obstruction
were searched using a fiber-optic scope. The endobronchial cuff was positioned just below the trachcal carina while the trachea
was intubated with a DLT (Rüsch). The distances of displacement, from the tracheal carina to the bronchial cuff, were measured
during anesthesia using an epidural catheter, which had marks every 5 mm. The distances for correcting the tube position were
measured at both the bronchial cuff and the level of the teethPaO2,PaCO2 andSPO2 were also measured.
Results Malposition (displacement over 5 mm from the correct position) was found in 42 patients, and 40 of them were in a withdrawal
direction, occurring at the postural change and during one-lung ventilation, especially during manipulation of the lung hilum.
Correcting distances at the level of the teeth were 15.3–3-times longer than those at the bronchial cuff. Airway deformities
and gradual withdrawal of the bronchial cuff were found in association with surgical manipulation. Obstruction occurred at
the tips of the tracheal tube in four patients and the bronchial tube in six patients, and at the tip of both in two patients.
Hypoxemia (PaO2<60 mmHg) occurred in four patients and hypercapnea (PaCO2>60 mm Hg) in two patients.
Conclusion Most of the DLT obstructions were associated with withdrawal malposition. Great attention to DLT displacement and airway deformity
is advised. 相似文献