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91.
SAGARA KATSURO; ARAKI KAZUFUMI; ETSUO MATSUNAGA; ETOH KENJI; FUJIYAMA SHIGETOSHI; KATAOKA KOUICHIRO; SAKAGUCHI USHIO 《Japanese journal of clinical oncology》1978,8(1):63-70
A 42-year-old woman with leiomyoblastoma of the stomach is described.She is living well for more than five years following operation.The clinical findings of 40 Japanese patients with leiomyoblastomawere also reviewed. In this series, the tumor was essentiallyseen in adults. The average age of the patients was 53, andthe sex ratio was equal. The most important and valuable diagnosticaid was roentogenography. The tumors are usually found in theantrum, but rarely in the cardia. Endoscopically, a polypoidmass, which is frequently umbilicated or ulcerated, can be visualized.The size of tumor varies from 1.2 cm to 11 cm in diameter andthe growth usually occurs singly. No metastatic case was found,but four had concomitant gastric cancer and two had gastricleiomyoma among the 40 Japanese cases. 相似文献
92.
KUSUMOTO SHIZUO; KOGA KENJI; TSUKINO HARUAKI; NAGAMACHI SHIGEKI; NISHIKAWA KIYOSHI; WATANABE KATSUSHI 《Japanese journal of clinical oncology》1986,16(4):319-323
Results of radiotherapy for lung cancer in the elderly werecompared with those in younger patients. A total of 129 patientswere treated by radiation therapy with or without chemotherapy.Fifty-six patients (43.4%) were 70 years old or more (elderlygroup) at the time of treatment, and the remaining 73 patientswere below age 70 (younger group). Treatment results in the elderly group were nearly the sameas those in the younger group in all stages of the disease.Survival time was longer for patients with performance status(PS) of 0 to 2 than for those with PS 3 or 4 regardless of age(p < 0.05). The survival time of the elderly group was nearlythe same as that of the younger group for squamous cell carcinoma,but somewhat shorter for adenocarcinoma although the differencewas not statistically significant. There was no difference insurvival between the two groups when they were treated by combinedradiation therapy and chemotherapy. Our results suggest thatelderly patients can be treated as safely as younger patientsby radiotherapy alone or combined radiation therapy and chemotherapy. 相似文献
93.
SHUNICHI SHIBATA KENJI FUKADA SHOICHI SUZUKI YASUO YAMASHITA 《Journal of anatomy》1997,191(4):561-570
We investigated the immunohistochemical localisation of types II and X collagen as well as the cytochemical localisation of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible on d 14–16 of pregnancy. On d 14 of pregnancy, although no immunostaining for types II and X collagen was observed, alkaline phosphatase activity was detected in all cells in the anlage of the future condylar process. On d 15 of pregnancy, immunostaining for both collagen types was simultaneously detected in the primarily formed condylar cartilage. Alkaline phosphatase activity was also detected in chondrocytes at this stage. By d 16 of pregnancy, the hypertrophic cell zone rapidly increased in size. These findings strongly support a periosteal origin for the condylar cartilage of the fetal mouse mandible, and show that progenitor cells for condylar cartilage rapidly or directly differentiate into hypertrophic chondrocytes. 相似文献
94.
TAISHI KUWAHARA M.D. ATSUSHI TAKAHASHI M.D. YOSHIHIDE TAKAHASHI M.D. ATUSHI KOBORI M.D. SHINSUKE MIYAZAKI M.D. ASUMI TAKEI M.D. TADASHI FUJINO M.D. KENJI OKUBO M.D. KATSUMASA TAKAGI M.D. AKIRA FUJII M.D. MASATERU TAKIGAWA M.D. YUJI WATARI M.D. HIROYUKI HIKITA M.D. AKIRA SATO M.D. KAZUTAKA AONUMA M.D. 《Journal of cardiovascular electrophysiology》2013,24(8):847-851
95.
MASAO TAKEMOTO M.D. § ATSUHIRO NAKASHIMA M.D. † § JUN MUNEUCHI M.D. ‡ § KEN-ICHIRO YAMAMURA M.D. ‡ § YUICHI SHIOKAWA M.D. † § KENJI SUNAGAWA M.D. RYUJI TOMINAGA M.D. † 《Pacing and clinical electrophysiology : PACE》2010,33(1):e4-e7
We report a pediatric patient with a congenitally corrected transposition of the great arteries (ccTGA)(SLL) in which permanent para-Hisian pacing (PPHP) could improve dyssynchrony-associated systemic ventricular (SV) dysfunction resulting from permanent morphologic left ventricular pacing for complete atrioventricular block. Since, in patients with ccTGA(SLL), an elongated His-bundle runs medially toward the upper septum to the site of the fibrous continuity between the right-sided mitral valve and pulmonary artery, the His-bundle may easily be captured by a pacing lead, unlike in normal hearts. Thus, PPHP may be an effective therapeutic strategy for the treatment of dyssynchrony-associated SV dysfunction associated with ccTGA (SLL). (PACE 2010; e4–e7) 相似文献
96.
MASAYUKI TSUCHIDA M.D. MASA‐AKI KAWASHIRI M.D. KATSUHARU UCHIYAMA M.D. KENJI SAKATA M.D. CHIAKI NAKANISHI M.D. TOSHINARI TSUBOKAWA M.D. SHU TAKABATAKE M.D. TETSUO KONNO M.D. HIDEKAZU INO M.D. MASAKAZU YAMAGISHI M.D. 《Journal of interventional cardiology》2010,23(3):264-270
Background: Although efforts have been focused on developing endovascular procedures by which intravascular devices such as stents could be effectively deployed, few data exist regarding devices for the nonsurgical retrieval of deployed stents. Therefore, we designed to enable retrieval of deployed stents without a surgical procedure. Methods: The device consisted of four components: ultra‐low profile forceps with 2.0 mm in diameter, conducting shaft with 1.8 mm in diameter, control handle by which the forceps is opened or closed, and a covering sheath. This device was designed to advance into the vessel lumen along a 0.014‐inch guidewire by over the wire fashion. Results: The forceps could firmly catch nonexpanded as well as expanded tubular‐type stents with open cells in an in vitro model that was 4.0 mm in diameter. Then, we used this device in porcine renal arteries with 2.5–5.0 mm in diameter. At first, a fragmented 0.014‐inch guidewire could be safely removed without vessel damage that was confirmed by intravascular ultrasound. This device could successfully remove four of five inappropriately and 11 of 14 appropriately deployed stents. Under these conditions, intravascular ultrasound demonstrated minor vessel wall dissection in two‐third of cases. Conclusions: These results demonstrate that the present device can be used for transluminal removal of foreign bodies such as nonexpanded as well as expanded stents in acute phase. Further miniaturization may enable using this type of device in the renal as well as coronary arteries. (J Interven Cardiol 2010;23:264–270) 相似文献
97.
KENJI SHIMADA FUMI MATSUMOTO AKIRA TOHDA KEIKO AINOYA 《International journal of urology》2005,12(7):631-636
PURPOSE: Urinary control after definitive repair of a cloacal anomaly is difficult to achieve. The present report aims to describe the clinical course of urinary control, and the need for the management of bladder dysfunction after reconstruction. METHODS: The present consecutive series consisted of 11 girls who underwent definitive repair of cloacal anomalies over a period of 11 years. Eight patients were associated with hydrocolpos. Radiological examination included a plain X-ray radiograph of the lumbosacral spine and a voiding cystourethrography with or without a urodynamic study. RESULTS: Reconstruction of the cloaca was performed on patients aged between 1 and 3 years using a posterior sagittal approach. Vaginal reconstruction was carried out 13 times in 11 patients using tubularized vaginal flap, distal rectal segment, perineal skin flap, or total urogenital sinus mobilization. Cystostomy or vesicostomy was carried out in four newborns/infants. Another seven patients could void spontaneously but incompletely with residual urine. Occult spinal dysraphism was found in five patients and hemisacrum in two patients. After definitive reconstruction, most patients acquired an adequate to normal bladder volume for 1-year-olds. Normal detrusor-sphincter function was seen in three patients. Detrusor areflexia was seen in two patients who underwent in utero vesico-amniotic shunt. Detrusor underactivity was observed in six patients. Bladder compliance was good in all patients except for one. No patients in the present series showed persistent urinary incontinence from the bladder neck or urethral dysfunction. CONCLUSION: It is postulated that wetting after definitive repair may be the result of overflow incontinence and poor bladder contractility rather than sphincter injury. The main clinical characteristic of bladder dysfunction was a failure to empty. We could not define the exact etiology, but iatrogenic injury from extensive dissection can lead to the higher risks of peripheral nerve damage. Accomplishment of definitive repair involves not only anatomical reconstruction, but also postoperative urinary control, including the initiation of clean intermittent catheterizations under repeated urodynamic evaluations. 相似文献
98.
KOJI NISHIZAWA TAKASHI KOBAYASHI KENJI MITSUMORI YOSHIHIRO IDE JUN WATANABE KEIJI OGURA 《International journal of urology》2005,12(5):506-508
A characteristic clinical course of a patient with micropapillary bladder cancer, a rare histological variant with high metastatic potential, is presented. An 80-year-old woman had locally advanced high-grade bladder cancer with a focal micropapillary variant identified which was treated with intra-arterial chemotherapy with radiation therapy. Standard follow-ups involving cystoscopy with cold-cup biopsies and computed tomography could not detail the bladder carcinoma; however, the patient died of carcinomatosis 20 months after treatment. At autopsy, carcinomas proliferated under benign mucosa and infiltrated diffusely in the retro peritoneum. This behavior differs from the normal pattern of invasive transitional cell carcinoma, which usually proliferates forming a mass lesion. Thus, it may be difficult to detect micropapillary bladder cancer by computed tomography which demonstrates only increased tissue density in retroperitoneal fascia; therefore, care should be taken in the follow-up of micropapillary bladder cancer. 相似文献
99.
KENJI HOSHINO KIYOSHI OGAWA TAKASHI HISHITANI REIKO KITAZAWA 《Pediatrics international》2003,45(1):39-44
BACKGROUND: There have been only a few investigations into the effects of cardiopulmonary bypass (CPB) on the magnesium (Mg) concentrations in pediatric patients. The purpose of the present study was to compare the postoperative Mg concentrations and their recovery time to pre-surgical values in pediatric patients undergoing CPB for surgical repair of congenital heart disease. The incidence of dysrhythmia was also determined. METHODS: Twenty-seven pediatric patients undergoing open-heart surgery with CPB were enrolled in this study. Controls were 23 pediatric patients undergoing palliative surgery without CPB. Serum Mg (SMg) concentrations and ionized Mg (iMg) concentrations were measured at four sample points: 24 h before the surgery, immediately after the surgery, 24 h after the surgery and 48 h after the surgery. RESULTS: Serum Mg and iMg concentrations were significantly decreased after open-heart surgery. Immediately after the surgery, the mean SMg concentration was 64.1% and the mean iMg concentration was 68.8% of the pre-surgical values. The concentration of iMg showed quicker recovery than that of SMg, and returned to normal range 48 h after surgery. However, SMg and iMg concentrations after palliative surgery did not show significant differences from the pre-surgical values. The incidence of dysrhythmia was almost the same between the two groups; dysrhythmia was observed in two patients in the open-heart surgery group and in three patients in the palliative surgery group. CONCLUSIONS: Mg concentrations showed significant decrease after CPB; however, they showed quick recovery and did not increase the incidence of dysrhythmia in pediatric patients. 相似文献
100.
SEIJI FUTAGAMI TETSURO HIRATSUKA KENJI SUZUKI MASANORI KUSUNOKI KEN WADA KAZUMASA MIYAKE KAZUSHI OHASHI MASUMI SHIMIZU HIDEMI TAKAHASHI KATYA GUDIS SHUNJI KATO TAKU TSUKUI CHOITSU SAKAMOTO 《Journal of gastroenterology and hepatology》2006,21(1):32-40
Background and Aims: The purpose of this study was to investigate possible factors that could impact on γδ T cell accumulation in the gastric mucosa. Method: Subjects were 22 Helicobacter pylori (H. pylori)‐free and 75 H. pylori‐infected mucosa biopsies classified into grades I~III gastritis as per our previous study. The number of γδ‐ and 45 RO‐positive T cells were determined by immunostaining. Gastric mucosal anti‐H. pylori urease specific antibodies and interleukin (IL)‐1β, IL‐2, 4, 7, 10 and IL‐12 levels were assayed by enzyme‐linked immunosorbent assay (ELISA). CC chemokine receptor 2 (CCR2) expression levels, migration, and cytokine production in γδ T cells stimulated by H. pylori urease were also evaluated. Results: The γδ T cell count was significantly higher in grade III gastritis which exhibits strong immunoglobulin (Ig)A and IgG responses to H. pylori urease with lymphoid follicles than in other groups. γδ T cell count was significantly correlated with IL‐1β and interleukin‐7 (IL‐7) levels in the gastric mucosa. H. pylori urease immunoreactivity was detected in lamina propria of grade III gastritis, along with many γδ T cells. After H. pylori eradication therapy, the γδ T cell count in grade III gastritis significantly decreased. H. pylori urease stimulated significant increases in CCR2 expression levels, although to a lesser degree than those induced by IL‐7 stimulation in both peripheral and mucosal γδ T cells. Interferon (IFN)‐γ and IL‐10 production was also stimulated by H. pylori urease in peripheral γδ T cells. Conclusions: Gastric mucosal increases in IL‐7 and IL‐1β closely corresponded to the accumulation of γδ T cells in gastric mucosa. An association was also seen between γδ T cell accumulation and H. pylori urease‐specific Ig levels. 相似文献