全文获取类型
收费全文 | 101297篇 |
免费 | 5171篇 |
国内免费 | 313篇 |
专业分类
耳鼻咽喉 | 1152篇 |
儿科学 | 2246篇 |
妇产科学 | 2184篇 |
基础医学 | 13517篇 |
口腔科学 | 3817篇 |
临床医学 | 7799篇 |
内科学 | 25121篇 |
皮肤病学 | 2394篇 |
神经病学 | 8680篇 |
特种医学 | 2303篇 |
外科学 | 13883篇 |
综合类 | 507篇 |
一般理论 | 35篇 |
预防医学 | 8607篇 |
眼科学 | 1836篇 |
药学 | 6675篇 |
中国医学 | 390篇 |
肿瘤学 | 5635篇 |
出版年
2024年 | 63篇 |
2023年 | 654篇 |
2022年 | 699篇 |
2021年 | 2038篇 |
2020年 | 1125篇 |
2019年 | 2012篇 |
2018年 | 3151篇 |
2017年 | 1995篇 |
2016年 | 2081篇 |
2015年 | 2755篇 |
2014年 | 3191篇 |
2013年 | 4380篇 |
2012年 | 8667篇 |
2011年 | 8931篇 |
2010年 | 4253篇 |
2009年 | 3301篇 |
2008年 | 7441篇 |
2007年 | 7668篇 |
2006年 | 7516篇 |
2005年 | 7108篇 |
2004年 | 6494篇 |
2003年 | 5984篇 |
2002年 | 5604篇 |
2001年 | 1750篇 |
2000年 | 2220篇 |
1999年 | 1203篇 |
1998年 | 446篇 |
1997年 | 333篇 |
1996年 | 335篇 |
1995年 | 297篇 |
1994年 | 237篇 |
1993年 | 219篇 |
1992年 | 211篇 |
1991年 | 181篇 |
1990年 | 129篇 |
1989年 | 128篇 |
1988年 | 102篇 |
1987年 | 89篇 |
1986年 | 95篇 |
1985年 | 122篇 |
1984年 | 148篇 |
1983年 | 110篇 |
1982年 | 141篇 |
1981年 | 126篇 |
1980年 | 129篇 |
1979年 | 66篇 |
1978年 | 68篇 |
1977年 | 67篇 |
1976年 | 56篇 |
1974年 | 65篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
31.
32.
33.
Teresa Nunes José Paulo Monteiro José Carlos Ferreira Pedro Vilela 《European radiology》2009,19(10):2551-2554
L1 disease is the most common genetic cause of congenital hydrocephalus. Mutations in the L1CAM gene are associated with an overlapping clinical spectrum of four X-linked neurological conditions, characterized by hydrocephalus, mental retardation, lower limb spasticity and adducted thumbs. Brain anomalies are frequently present in L1 disease. We describe these anomalies by reporting a case of a male newborn presenting with congenital hydrocephalus along with corpus callosum agenesis and enlargement of the massa intermedia. These findings, in association with the presence of clasped thumbs, raised the suspicion of L1 disease, which was confirmed by the detection of a mutation in the L1CAM gene. In cases of congenital hydrocephalus, recognition of the brain anomalies associated with L1 disease may contribute to pursuing the genetic analysis needed for the diagnosis and genetic counseling. 相似文献
34.
35.
36.
Raúl González-García Francisco J Rodríguez-Campo Verónica Escorial-Hernández Mario F Mu?oz-Guerra Jesús Sastre-Pérez Luis Naval-Gías José L Gil-Díez Usandizaga 《Journal of oral and maxillofacial surgery》2006,64(11):1587-1591
PURPOSE: Temporomandibular joint (TMJ) arthroscopy has been considered a safe surgical procedure in the treatment of TMJ derangement. However, it is not exempt from complications. This study evaluates the complications of arthroscopy in patients with internal derangement of TMJ. PATIENTS AND METHODS: Five hundred consecutive patients (670 joints) with TMJ derangement who underwent arthroscopy between 1995 and 2004 were retrospectively analyzed. All the patients were classified as II to V in the Wilkes classification. Lysis and lavage, electrocautery of the posterior ligament, injection of corticoids, injection of ethanolamine, myotomy of lateral pterygoid muscle attachments, myotomy and electrocautery, motor debridement, injection of sodium hyaluronate, and meniscal suture were performed in different patients. RESULTS: Complications were recognized during or immediately after the surgery. They were observed in 5 of 341 (1.26%) arthroscopies of the right TMJ and 4 of 329 (1.21%) arthroscopies of the left TMJ. A 1.34% complication rate was found in the whole series. No blood clots within the external auditory canal were observed. Bleeding within the superior TMJ space was observed in 57 cases (8.5%), 36 of them in the right TMJ and 21 in the left TMJ, but they were not considered as true complications. Lacerations of the external auditory canal were found in 2 cases (0.3%), with no cases of perforation of the tympanic membrane. Lesion of the auriculotemporal nerve was observed in a case. Paresia of the facial nerve was found in 4 cases (0.6%). Alteration of visual accuracy of the ipsilateral eye was also observed in a patient immediately after the surgery. CONCLUSION: Special care must be taken to reduce complications within the upper joint space by means of an adequate instrumentation and by paying attention to essential points of the arthroscopic technique. 相似文献
37.
Esparza-Gordillo Jorge; Goicoechea de Jorge Elena; Buil Alfonso; Berges Luis Carreras; Lopez-Trascasa Margarita; Sanchez-Corral Pilar; Rodriguez de Cordoba Santiago 《Human molecular genetics》2005,14(8):1107
Some MCP SNP and aHUS-associated MCP mutation 相似文献
38.
Selene Dall' Acqua Coutinho José Daniel Fedullo Sandra Helena Corrêa 《Medical mycology》2006,44(4):383-387
The objective of this study was to determine the presence of different species of the genus Malassezia in the healthy external auditory canal of wild felids maintained in captivity. One hundred and thirty-two adult animals (264 samples of cerumen), 77 males (58.3%) and 55 females (41.7%), were studied: large felids (55 animals) - 26 lions (Panthera leo), 13 tigers (Panthera tigris), 6 leopards (Panthera pardus), 6 jaguars (Panthera onca), 2 cheetahs (Acinonyx jubatus), 2 pumas (Puma concolor); small felids (77 animals) - 29 tiger cats (Leopardus tigrinus), 19 jaguarundis (Herpailurus yagouaroundi), 10 margays (Leopardus wiedii), 9 pampas cats (Oncifelis colocolo), 6 geoffroy's cats (Oncifelis geoffroyi), and 4 servals (Leptailurus serval). Samples were obtained by the introduction of a sterile swab into the ear canal after cleaning the auricle with an alcohol-ether solution. The swabs were seeded onto Petri dishes containing modified Mycosel agar and sterile olive oil was added to the surface of the medium before specimen seeding. The plates were incubated at 35oC for two weeks. The isolates were analyzed regarding macro-and micromorphology and identified through catalase tests and growth on Tween 20, 40, 60 and 80. Malassezia spp. were isolated from 58 of the felids studied (43.9%) and from 102 samples of cerumen (38.6%). Malassezia sympodialis was isolated exclusively in large felids (33 animals-56.9%), and Malassezia pachydermatis exclusively in smaller varieties (25 animals - 43.1%). The incidence of fungi was higher in lions, with yeast being isolated in 25 of 26 animals (96.2%). Forty-eight strains (47.1%) were isolated from the right ear canal and 54 (52.9%) from the left. Although M. pachydermatis is the species considered a member of the microbiota of the mammalian external ear canal these results suggest that M. sympodialis participates in the microbiota of large felids. 相似文献
39.
Guntur E Luis Chee-Khuen Yong Deepak A Singh S Sengupta David SK Choon 《Journal of orthopaedic surgery and research》2007,2(1):22-10
Background
Acromioclavicular injuries are common in sports medicine. Surgical intervention is generally advocated for chronic instability of Rockwood grade III and more severe injuries. Various methods of coracoclavicular ligament reconstruction and augmentation have been described. The objective of this study is to compare the biomechanical properties of a novel palmaris-longus tendon reconstruction with those of the native AC+CC ligaments, the modified Weaver-Dunn reconstruction, the ACJ capsuloligamentous complex repair, screw and clavicle hook plate augmentation. 相似文献40.
Expression of activation molecules in neutrophils, monocytes and lymphocytes from patients with unstable angina treated with stent implantation. 总被引:1,自引:0,他引:1
Víctor Sánchez-Margalet José M Cubero Consuelo Martín-Romero José Cubero José M Cruz-Fernández Raimundo Goberna 《Clinical chemistry and laboratory medicine》2004,42(3):273-278
Coronary angioplasty is known to mediate an inflammatory response. Recently, we have characterized the transient systemic inflammatory response after coronary stent implantation in patients with unstable angina by measuring different soluble protein markers. In the present study we have characterized the expression of various cellular activation markers in neutrophils, monocytes and lymphocytes from the same group of patients. Peripheral blood samples were taken before and 24 h, 48 h and 7 days after successful coronary stenting in 58 patients. Cell surface markers (CD11b/CD18 and CD38) were analyzed by flow cytometry to determine the activation of neutrophils, monocytes and T lymphocytes. We found that coronary angioplasty with stent implantation produces an increase in the cell surface expression of CD11b/CD18 in neutrophils and CD38 in monocytes, following a similar time-course with a peak after 24 h, returning to basal levels after 48 h and a second peak after 7 days. However, T lymphocytes were not found to be activated. These results suggest that coronary stent implantation induces a different pattern inducing soluble and cellular inflammation markers, and therefore, they should be taken into account in patients undergoing stent implantation to study clinical correlations. 相似文献