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81.
82.
Jalal Zamani M.D. Ahmad Ali Amirghofran M.D. Ali Reza Moaref M.D. Sasan Afifi M.D. Gholam Reza Rezaian M.D. F.I.C.A. 《Journal of cardiac surgery》2010,25(6):670-671
Abstract The combination of posttraumatic coronary artery‐right ventricular fistula and multiple ventricular septal defects is a rare and interesting phenomenon. We describe a case of a 19‐year‐old male with these findings following a blunt chest trauma after a motorcycle accident . (J Card Surg 2010;25:670‐671) 相似文献
83.
N. Li A. Tieng S. Novak A. Fernandes P.K. Jalal M. Akerman K. Sideridis S. Bank 《Pancreatology》2010,10(2-3):238-242
Background and Aims: Drug-induced pancreatitis accounts for about 2% of acute pancreatitis. The aim of this study is to determine whether propofol and other medications are associated with increased risk for post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. Methods: A retrospective study was conducted at a single tertiary care hospital. All patients who underwent ERCP from 2001 to 2004 were included. Diagnosis of acute post-ERCP pancreatitis was based on a consensus definition. Results: A total of 506 patients underwent ERCP. The total incidence of post-ERCP pancreatitis was 7.1%. There was no significant difference in post-ERCP pancreatitis between patients who received propofol compared to patients who received midazolam and fentanyl (9.0 vs. 5.9%, p = 0.18). Patients receiving an angiotensin receptor blocker were approximately 4 times more likely to develop post-ERCP pancreatitis (OR = 4.1, 95% CI 1.6–10.9). Patients younger than 65 years and smokers also had higher risk of developing acute post-ERCP pancreatitis than those who were older than 65 years (OR = 3.9, 95% CI 1.7–9.1) and non-smokers (OR = 2.8, 95% CI 1.3–6.2). Conclusions: Propofol is a safe sedative drug for ERCP without additional risk of developing acute post-ERCP pancreatitis. Use of angiotensin receptor blockers, smoking and younger age are independent risk factors for post-ERCP pancreatitis. 相似文献
84.
Ghali JK Massie BM Mann DL Rich MW 《Journal of the American College of Cardiology》2010,56(25):2077-2080
Guidelines have rather quickly assumed a central role in health care delivery in the U.S. They have become the foundation on which performance measures are built and, therefore, a major player in assessing the quality of care provided by individuals and institutions, the ramifications of which involve reputation, reimbursement, and litigation. We are concerned, however, that in our enthusiasm for collectively endorsing these guidelines, we are marginalizing the importance of physician judgment and inadvertently risking the conversion of guidelines into "cookbooks." We believe that this viewpoint, while unequivocally acknowledging the fundamental importance of guidelines, simultaneously provides a critically important perspective on the potential for misuse of both guidelines and performance measures. Further, we hope that publication of this viewpoint will help temper enthusiasm for overzealous conversion of guidelines into performance measures, thereby restoring the vital role of physician judgment and insight into patient management. 相似文献
85.
Seraj JM Yazdani N Ashtiani ZO Seraj SM Hasheminasab SM Memar B Mirashrafi F Borghei H Yazdani J Mostaan LV 《Pathology, research and practice》2011,207(12):758-761
In this study, we investigated the prevalence of human papilloma virus (HPV) infection and TP53 expression in patients with squamous cell carcinoma (SCC) of the tongue and, subsequently, its significance in cervical lymph node metastases and tumor differentiation. Sections of formalin-fixed, paraffin-embedded tissue blocks from 94 histologically confirmed tongue SCC cases were investigated in this study. Immunohistochemistry was used to study TP53 expression, and polymerase chain reaction (PCR) was performed for the detection of high risk HPV types (16 and 18). The frequency of HPV-16 and HPV-18 infection was 10.6% and 16%, respectively. Overexpression of TP53 was observed in 70.2% of patients. Young patients (aged below 45 years) comprised 20% of all patients. There was no significant association between TP53, HPV-16, or HPV 18 presence and higher stages of the tumor, tumor differentiation, or presence of nodal metastasis. Although an association between head and neck SCC and HPV infection is being recognized and reported, our data implicate that HPV infection or TP53 expression does not play a significant role in oral tongue SCC pathogenesis, differentiation, or metastasis, as seen in our patients. 相似文献
86.
Ghali JK 《The New England journal of medicine》2011,365(5):470; author reply 470-470; author reply 471
87.
Behzad Einollahi Mahboob Lessan-Pezeshki Mohammad Hossein Nourbala Naser Simforoosh Vahid Pourfarziani Eghlim Nemati Mohsen Nafar Abbas Basiri Fatemeh Pour-Reza-Gholi Ahmad Firoozan Mohammad Hassan Ghadiani Khadijeh Makhdoomi Ali Ghafari Pedram Ahmadpour Farshid Oliaei Mohammad Reza Ardalan Atieh Makhlogh Hamid Reza Samimagham Jalal Azmandian 《International urology and nephrology》2009,41(3):679-685
Introduction Kaposi’s sarcoma (KS) is one of the most common tumors to occur in kidney recipients, especially in the Middle East countries.
Limited data with adequate sample size exist about the development of KS in living kidney recipients.
Methods Therefore, we made a plan for a multicenter study, accounting for up to 36% (n = 7,939) of all kidney transplantation in Iran, to determine the incidence of KS after kidney transplantation between 1984
and 2007.
Results Fifty-five (0.69%) recipients who developed KS after kidney transplantation were retrospectively evaluated with a median follow-up
of 24 (1–180) months. KS occurred more often in older age when compared to patients without KS (49 ± 12 vs. 38 ± 15 years,
P = 0.000). KS was frequently found during the first 2 years after transplantation (72.7%). Skin involvement was universal.
Furthermore, overall mortality rate was 18%, and it was higher in patients with visceral involvement compared to those with
mucocutaneous lesions (P = 0.01). However, KS had no adverse affect on patient and graft survival rates compared to those without KS. Forty-four patients
with limited mucocutaneous disease and four with visceral disease responded to withdrawal or reduction of immunosuppression
with or without other treatment modalities. Renal function was preserved when immunosuppression was reduced instead of withdrawn
in patients with and without visceral involvement (P = 0.001 and 0.008, respectively).
Conclusion The high incidence of KS in this large population studied, as compared to that reported in other transplant patient groups,
suggests that genetic predisposition may play a pathogenetic role. 相似文献
88.
Aniba K Ghannane H Jalal H Belhaj Z Ousehal A Lmejjati M Benali SA 《Neuro-Chirurgie》2009,55(3):337-339
Background
Isolated central nervous system (CNS) tuberculoma is rare. Central nervous system tuberculosis (TB) is associated with high morbidity and mortality despite modern methods of detection and treatment. The authors report a case of a giant cerebellar tuberculoma mimicking a malignant tumor and review the literature.Observation
A six-year-old girl, with no past medical history, vaccinated for her age, presented with a three-month history of occipitocervical cephalalgia, complicated by gait disturbances. The MRI showed a left cerebellar tumor suggestive of a medulloblastoma. At surgery, a nodular, avascular lesion was found and pathological examination confirmed tuberculoma. Intracranial tuberculoma is an uncommon variety of central nervous system tuberculosis. The prognosis is related to the rapidity of diagnosis, surgical resection and the complementary antituberculosis treatment.Conclusion
Intracranial tuberculoma is an uncommon variety of central nervous system infection. Prognosis is improved by a quick diagnosis, surgical removal, and associated antituberculoma therapy. 相似文献89.
90.
Jalal H Stephen H Bibby DF Sonnex C Carne CA 《International journal of STD & AIDS》2007,18(9):617-621
High-risk subtypes of human papillomavirus (HPV) are the main causative agents of cervical cancer, for which Chlamydia trachomatis (CT) may sometimes be a co-factor. Vaccines have been developed against some subtypes of human papillomavirus and a vaccine against CT is in development. The objective of this study was to determine the prevalence of the subtypes of HPV and CT in genitourinary (GU) medicine clinic attenders. In total, 1000 consecutive patients attending the GU clinic participated in this anonymized point-prevalence study. Urethral swabs from 437 men and urethral plus cervical swabs as a single specimen from 563 women were tested for the subtypes of both organisms. Nested major outer membrane protein (MOMP) polymerase chain reaction detected CT chromosomal DNA in 44/437 (10%) of the men and 73/563 (13%) of the women. Genotypes E, F, and D were the most common. In all, 55/437 (13%) of men and 244/563 (43%) of women were infected with at least one high-risk HPV type. In conclusion, the new HPV vaccines, Gardasil and Cervarix, would have protected against 58% and 45%, respectively, of the high-risk subtypes found in women in this population. The rate of high-risk HPV infection (43%) found in women in this study raises concern. 相似文献