全文获取类型
收费全文 | 8114篇 |
免费 | 447篇 |
国内免费 | 124篇 |
专业分类
耳鼻咽喉 | 55篇 |
儿科学 | 182篇 |
妇产科学 | 643篇 |
基础医学 | 911篇 |
口腔科学 | 128篇 |
临床医学 | 938篇 |
内科学 | 1674篇 |
皮肤病学 | 89篇 |
神经病学 | 525篇 |
特种医学 | 262篇 |
外科学 | 1072篇 |
综合类 | 185篇 |
预防医学 | 413篇 |
眼科学 | 86篇 |
药学 | 632篇 |
中国医学 | 115篇 |
肿瘤学 | 775篇 |
出版年
2023年 | 40篇 |
2022年 | 96篇 |
2021年 | 180篇 |
2020年 | 96篇 |
2019年 | 149篇 |
2018年 | 251篇 |
2017年 | 169篇 |
2016年 | 162篇 |
2015年 | 216篇 |
2014年 | 248篇 |
2013年 | 387篇 |
2012年 | 568篇 |
2011年 | 583篇 |
2010年 | 384篇 |
2009年 | 321篇 |
2008年 | 496篇 |
2007年 | 574篇 |
2006年 | 544篇 |
2005年 | 440篇 |
2004年 | 380篇 |
2003年 | 319篇 |
2002年 | 313篇 |
2001年 | 270篇 |
2000年 | 273篇 |
1999年 | 210篇 |
1998年 | 64篇 |
1997年 | 68篇 |
1996年 | 71篇 |
1995年 | 35篇 |
1994年 | 49篇 |
1993年 | 36篇 |
1992年 | 132篇 |
1991年 | 99篇 |
1990年 | 73篇 |
1989年 | 45篇 |
1988年 | 51篇 |
1987年 | 47篇 |
1986年 | 44篇 |
1985年 | 30篇 |
1984年 | 35篇 |
1983年 | 13篇 |
1982年 | 10篇 |
1981年 | 13篇 |
1980年 | 7篇 |
1979年 | 16篇 |
1977年 | 7篇 |
1976年 | 5篇 |
1973年 | 7篇 |
1972年 | 7篇 |
1971年 | 10篇 |
排序方式: 共有8685条查询结果,搜索用时 0 毫秒
981.
Wang JY Hsieh JS Tsai KB Huang YS Hou MF Huang TJ 《The Kaohsiung journal of medical sciences》2001,17(6):327-330
Primary abscess of the omentum is an infrequent disease entity. We report a case of 60-year-old male patient who suffered from left lower quadrant abdominal pain with localized abdominal wall tenderness, nausea and high-grade fever for the previous few days. Computerized tomography scan revealed a heterogeneous lesion that adhered to the abdominal wall. A pre-operative diagnosis of colonic diverticulitis complicated with intra-abdominal abscess was made and a laparotomy was done. At surgical exploration, an indurate mass consisting of abscess within the omentum was identified. The surgical procedure consisted of resection of the omental abscess with abdominal wall debridement, and subsequent antimicrobial therapy was administered. Postoperatively, the patient recovered uneventfully. Clinicians who treated such patients should be aware of this problem because of the difficulty of preoperative diagnosis. 相似文献
982.
Waist-to-height ratio, a simple and practical index for assessing central fat distribution and metabolic risk in Japanese men and women 总被引:4,自引:0,他引:4
OBJECTIVE: The normal body mass index (BMI) range, as defined by the World Health Organization (WHO), is quite wide, and some people within this range may have excessive central fat accumulation and elevated metabolic risks. We hypothesize that the waist-to-height ratio (W/Ht), an effective index for assessing central fat distribution among Japanese people, can be used to identify subjects who are at higher metabolic risk within the normal as well as the overweight range. METHODS: We investigated: (1). the values of BMI, waist circumference, and W/Ht in 6141 men and 2137 women at various age intervals and calculated gender (female to male) ratios for all these anthropometric indices; (2). the relation between age and each anthropometric index, between age and morbidity index for coronary risk factors (sum of the scores for hyperglycemia, hypertension, hypertriglyceridemia, hypercholesterolemia, and low HDL cholesterol; one point for each condition if present), and between morbidity index for coronary risk factors and each anthropometric index; (3). the distributions of the subjects, using various proposed indices of waist circumference (those suggested by WHO, the Japan Society for the Study of Obesity, and the Asia-Pacific perspective), and our proposed boundary value, W/Ht 0.5, among the WHO categories based on BMI; (4). the metabolic risks (coronary risk factors, hyperuricemia, high gamma-glutamyltransferase, and fatty liver diagnosed by ultrasonography), and exercise habits among normal-weight subjects with W/Ht<0.5 or >or=0.5. RESULTS: (1). For the various anthropometric indices in all age groups, the gender ratio for W/Ht was closest to 1, indicating that a single set of values for W/Ht can be used for men and women. (2). Height correlated negatively with age. Among the anthropometric indices, only W/Ht correlated positively with age for both men and women, while age and all anthropometric indices, except height, correlated positively with the morbidity index for coronary risk factors. For both men and women, the highest correlation coefficient was between W/Ht and the morbidity index for coronary risk factors. (3). Nearly all overweight men and women (BMI>or=25) had W/Ht>or=0.5 (98.5% of men and 97.5% of women). None of the underweight subjects had W/Ht>or=0.5. However, 45.5% of men and 28.3% of women of normal weight (BMI 18.5-<25) had W/Ht>or=0.5. W/Ht, of all the indices investigated, was the best index for signaling metabolic risk in the normal-weight subjects as well as the overweight subjects. (4). Age- and BMI-adjusted odds ratios for multiple metabolic risks, and history of no habitual exercise were significantly higher in normal-weight men and women with W/Ht>or=0.5 than in others of normal weight. CONCLUSIONS: Waist circumference is improved by relating it to height to categorized fat distribution of different genders and ages. W/Ht is a simple and practical anthropometric index to identify higher metabolic risks in normal and overweight Japanese men and women. 相似文献
983.
Ada C. Mezzich Ralph E. Tarter Ya-Chen Hsieh Amy Fuhrman 《The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions》1992,1(3):217-221
The authors investigated the association between age at menarche and age at onset of substance use with frequency of alcohol consumption in mid-adolescence; age at first DSM-III-R diagnosis of psychoactive substance use disorder (PSUD); severity of physical health, substance use, and psychosocial problems; and psychiatric disorders in female adolescents. Twenty-eight PSUD female adolescents (age 14–18 years) were studied. Chronological age at first substance use, and not age at menarche, was associated with the four variables mentioned above. These findings indicate that substance use in this population is encompassed within significant psychiatric disturbance that most commonly precedes the onset of PSUD. 相似文献
984.
We studied serum free C-peptide immunoreactivity (CPR) and the coefficient of variation (CV) of fasting blood glucose values (FBG) in 26 insulin-treated patients with non-insulin-dependent diabetes mellitus (NIDDM) in relation to the duration of insulin treatment. Serum free CPR responses during 100 g oral glucose tolerance test (OGTT) were significantly lower in patients with insulin treatment for five years or more than in those with insulin treatment for less than five years although their previous immunoreactive insulin (IRI) responses during OGTT before insulin treatment showed no significant difference. CV of FBG was found to be significantly higher at the time of this study (20.6 +/- 7.8%, mean +/- SD) than at the second year of insulin treatment (15.3 +/- 7.7%, P less than 0.05) in the patients with insulin treatment for five or more years but did not show any significant difference in patients with insulin treatment for less than five years at the corresponding times. Thus we measured CV of the FBG in NIDDM patients at various intervals during the long-term insulin or oral hypoglycemic agent treatment in another study. In 20 patients with insulin treatment, CV of FBG was found to be significantly different among the various intervals during insulin treatment (P less than 0.0025). It was significantly higher at the eight year (22.2 +/- 8.6%) and 12th year (21.9 +/- 9.1%) than at the second year (14.9 +/- 6.1%) and fifth year (15.0 +/- 6.7%) of insulin treatment (P less than 0.025, P less than 0.025; P less than 0.05, P less than 0.01, respectively).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
985.
Pneumonia following closed head injury. 总被引:7,自引:0,他引:7
A H Hsieh M J Bishop P S Kubilis D W Newell D J Pierson 《The American review of respiratory disease》1992,146(2):290-294
Pneumonia is common among patients with artificial airways in place. Most prior studies of such pneumonia involve a heterogeneous group of patients, usually with major medical or surgical illnesses. We studied the incidence of pneumonia in a group of patients with isolated closed head injury (CHI) in an effort to determine the pattern of the problem in the absence of other injuries and to determine whether the pattern of development of pneumonia in these patients was comparable to that in more heterogeneous groups of mechanically ventilated patients. We studied 109 initially comatose patients with isolated CHI who were ventilated 24 h or more. The mean age was 30.3 +/- 20.2 yr, 72% were male, and the admission Glasgow coma score was 4.9T +/- 1.4. Overall, 45 patients (41%) developed pneumonia, with the majority (29/45) occurring during the first 3 days of hospitalization. No patient developed pneumonia after the first week despite the fact that many were still ventilated, others remained intubated, and yet others were extubated but comatose. Patients who developed pneumonia experienced a longer ICU stay (10.5 +/- 5.4 days versus 7.2 +/- 4.3 days, p = 0.001) and hospital stay (34.8 +/- 27.6 versus 22.5 +/- 20.2 days, p = 0.01).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
986.
Huang JF Wang LY Lin ZY Chen SC Hsieh MY Chuang WL Yu MY Lu SN Wang JH Yeung KW Chang WY 《Journal of gastroenterology and hepatology》2002,17(2):190-195
BACKGROUND: To elucidate the incidence of the rare cases of icteric type hepatocellular carcinoma (IHCC), we conducted a retrospective study. The clinical outcomes of IHCC cases were also analyzed. METHODS: From January 1986 to December 1997, newly diagnosed HCC cases were evaluated and reviewed from an admission registration database in a medical center. Patients who had HCC tumors which were located within biliary tracts, and caused obstructive jaundice as the initial clinical manifestation of HCC, were defined as cases of IHCC. Besides clinical manifestations, the outcomes and survival times of various treatment strategies among the IHCC cases were compared retrospectively. RESULTS: The incidence of IHCC was 0.53% (10/1897). The median age of the 10 IHCC patients (seven men, three women) was 56.1 years (range = 41-72 years). Most primary HCC lesions (80%) were of expansive type: either single nodular type or multinodular type. All the patients eventually died of cholangitis and sepsis. Besides biliary drainage, seven patients of moderate to good liver reserve function received transarterial chemoembolization (TACE) for palliative treatment, and three of these received additional radiotherapy (R/T) because of the limited effect of TACE (total dosage ranged from 1600 to 5000 cGy). One patient received only radiotherapy (total dosage 1600 cGy) because of having a single tumor and poor liver reserve function. The median survival time among those eight patients who received palliative treatment was 13.4 months (range = 8-26 months), which was significantly longer than for the other two patients without treatment (2 and 4 months). CONCLUSIONS: Icteric type hepatocellular carcinoma (IHCC) is a rare presentation of HCC. Palliative treatment strategies, including TACE and/or R/T showed a beneficial effect in improving the survival time. 相似文献
987.
Gaydos CA Hsieh YH Galbraith JS Barnes M Waterfield G Stanton B 《International journal of STD & AIDS》2008,19(10):704-710
A community-based intervention, Focus-on-Kids (FOK) has demonstrated risk-behaviour reduction of urban youth. We modified FOK to Focus-on-Teens (FOT) for high schools. High school adolescents (n=1190) were enrolled over successive school semesters. The small-group sessions were presented during the school-lunch hours. Confidential surveys were conducted at baseline, immediate, six-, and 12-month postintervention for demographics, parental communication/monitoring, sexual risk behaviours and sexually transmitted diseases (STDs)/HIV/condom-usage knowledge. Sexually active participants were encouraged to volunteer for urine-based STDs testing at the School-Based Health Centres. Many (47.4%) students reported having had sexual intercourse at baseline. Overall behaviours changed towards 'safer' sex behaviours (intent-to-use and using condoms, communicating with partner/parents about sex/condoms/STDs) with time (P<0.05). Proportion of students with complete correct knowledge of STDs/HIV increased to 88% at time 4 from 80% at baseline after adjusting for age, gender and sexual activity (P<0.05). High prevalence of STDs was detected in 875 participants who reported for urine testing at time 1: trichomonas, 11.8%; chlamydia, 10.1% and gonorrhoea, 4.1%. Prevalence decreased significantly for 310 participants who re-tested; chlamydia: 27.4% to 6.1% and gonorrhoea: 11.3% to 3.2%. FOT was successfully implemented as an STDs/HIV risk-reduction intervention. Sustained improvements of knowledge about STDs/HIV/condom usage, decreases in sexual risk behaviours supported the effectiveness of this intervention. 相似文献
988.
989.
Pancreatitis related to antiphospholipid antibody syndrome in a patient with systemic lupus erythematosus. 总被引:3,自引:0,他引:3
A 39-year-old woman was admitted with abdominal pain and dyspnea, and a diagnosis of systemic lupus erythematosus with renal involvement was established. Laboratory tests revealed highly elevated anticardiolipin antibody, thrombocytopenia and false positive VDRL. Generalized thrombus formation and Libman-Sacks endocarditis were found at postmortem examination. The pancreas showed chronic inflammation with thrombi in pancreatic arteries, but no vasculitic change was observed. Lowering of pancreatic blood flow because of arterial thrombi was a possible cause of pancreatitis in this patient. The spectrum of antiphospholipid antibody associated diseases may be extended to include pancreatitis as a thrombotic complication. 相似文献
990.
Chi-Yin Cheng Gran-Hum Chen Chi-Sen Chang Chih-Chien Tseng Hsi-Kuang Pan Chih-Kuen Huang Pao-Fu Hsieh 《Journal of gastroenterology》1994,29(4):474-478
Between August 1983 and December 1991 at the Taichung Veterans General Hospital, Taiwan, 65 advanced hepatocellular carcinoma
(HCC) patients with esophageal variceal bleeding received endoscopic injection sclerotherapy (EIS) and 60 such patients received
conservative medical treatment without EIS. The rate of successful control of acute bleeding was 72.5% (27/40 patients) in
the EIS group and 56.7% (34/60 patients) in the non-EIS group. The rebleeding rate was lower in the EIS group than in the
non-EIS group (26.9% vs 73.5%). Thirty-one of the EIS and 44 of the non-EIS treatment patients, mainly Child's B and C patients,
died within 2 months after the first bleeding. In the short term, EIS decreased the mortality due to esophageal variceal bleeding,
but the survivors still had to face hepatic failure and tumor growth. Thus, benefits of EIS were noted on short-but not on
long-term survival. The mean survival times were 2.38 months for the EIS group and 1.79 months for the non-EIS group. Since
EIS had no beneficial effects on long-term survival it is doubtful whether sclerotherapy applied to esophageal variceal bleeding
in patients with advanced HCC would be worthwhile, as the endoscopic procedure would only add to their suffering. 相似文献