全文获取类型
收费全文 | 984篇 |
免费 | 73篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 21篇 |
妇产科学 | 14篇 |
基础医学 | 142篇 |
口腔科学 | 36篇 |
临床医学 | 117篇 |
内科学 | 176篇 |
皮肤病学 | 12篇 |
神经病学 | 93篇 |
特种医学 | 21篇 |
外科学 | 94篇 |
综合类 | 39篇 |
现状与发展 | 1篇 |
预防医学 | 116篇 |
眼科学 | 5篇 |
药学 | 60篇 |
中国医学 | 9篇 |
肿瘤学 | 107篇 |
出版年
2024年 | 2篇 |
2023年 | 6篇 |
2022年 | 26篇 |
2021年 | 27篇 |
2020年 | 26篇 |
2019年 | 34篇 |
2018年 | 21篇 |
2017年 | 9篇 |
2016年 | 27篇 |
2015年 | 22篇 |
2014年 | 29篇 |
2013年 | 62篇 |
2012年 | 79篇 |
2011年 | 83篇 |
2010年 | 45篇 |
2009年 | 48篇 |
2008年 | 77篇 |
2007年 | 60篇 |
2006年 | 69篇 |
2005年 | 71篇 |
2004年 | 47篇 |
2003年 | 36篇 |
2002年 | 40篇 |
2001年 | 20篇 |
2000年 | 16篇 |
1999年 | 11篇 |
1998年 | 4篇 |
1997年 | 4篇 |
1995年 | 7篇 |
1994年 | 6篇 |
1993年 | 3篇 |
1992年 | 5篇 |
1991年 | 9篇 |
1990年 | 4篇 |
1989年 | 8篇 |
1988年 | 6篇 |
1987年 | 5篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 3篇 |
1982年 | 1篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1976年 | 2篇 |
排序方式: 共有1071条查询结果,搜索用时 31 毫秒
41.
Liisa M. Valsta Heli Tapanainen Teea Kortetmki Laura Sares-Jske Laura Paalanen Niina E. Kaartinen Peppi Haario Minna Kaljonen 《Nutrients》2022,14(7)
Information on dietary adequacy is needed to assess food and nutrition security in a modern society, especially in the transition towards climate-friendly food systems. In this study, differences in the nutritional adequacy of diets among Finnish adults were evaluated in population groups of different education, income and urbanisation levels. The study used data from the FinDiet 2017 Survey (n = 1655, 18–74 years). Modelled usual intakes of foods and nutrients were evaluated relative to food-based dietary guidelines issued by the National Nutrition Council of Finland (FNNC) and with respect to nutrient adequacy following the Nordic Nutrition Recommendations and FNNC. For about half of the nutrients studied, intakes were found to be adequate. Intakes of protein, fat, saturated fatty acids and salt were estimated to be high. By contrast, inadequate intakes were seen in folate and vitamins A, D, B1, B2 and C in almost all groups studied. Groups with a higher education and income, groups that lived in urban areas and, in particular, women adhered more closely to recommended food consumption and nutrient intakes than others. However, major challenges posed by the Finnish diet are common to all groups studied, and only certain dietary features evaluated in view of nutritional adequacy are associated with socioeconomic differences. 相似文献
42.
43.
Tiina Mattila Markku Heliövaara Harri Rissanen Paul Knekt Pauli Puukka Tuula Vasankari 《COPD》2017,14(2):143-149
There is little long-term follow-up data concerning the association between past pulmonary tuberculosis (TB), airway obstruction and mortality. We aimed to analyse a national health examination survey data from 6701 adult Finns undergoing spirometry between 1978 and 1980 (follow-up through 2013). We identified TB either through a disease history or by a TB-indicative scar on a chest x-ray. We specified obstruction using the lower limit of normal (LLN) and classified severity using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages 1–4. After adjusting for smoking and other confounders, past TB associated with obstruction. Compared to non-TB patients, the adjusted odds ratio (OR; 95% CI) of obstruction reached 2.21 (1.52–3.21) among patients with a scar recorded by one radiologist, 2.48 (1.63–3.78) when recorded by both radiologists and 4.59 (2.86–7.37) among patients with a disease history. Among those with neither past TB nor obstruction, with past TB only, with an obstruction only and with both, we found hazard ratios (HRs; 95% CIs) for subsequent mortality of 1.00 (reference), 1.11 (1.03–1.20), 1.62 (1.31–2.00) and 1.77 (1.45–2.16), adjusted for age, gender, smoking, body mass index (BMI), physical activity, education and general health. In conclusion, past TB strongly determines obstruction, although on its own quite weakly predicts premature death. TB and obstruction combined predict an additive mortality pattern. 相似文献
44.
Urho M. Kujala Jyrki Kettunen Heli Paananen Teuvo Aalto Michele C. Batti Olli Impivaara Tapio Videman Seppo Sarna 《Arthritis \u0026amp; Rheumatology》1995,38(4):539-546
Objective. To determine the relationship between different physical loading conditions and findings of knee osteoarthritis (OA). Methods. We selected 117 male former top-level athletes (age range 45–68 years) who had participated in sports activities with distinctly different loading conditions: 28 had been long-distance runners, 31 soccer players, 29 weight lifters, and 29 shooters. Histories of lifetime occupational and athletic knee loading, knee injuries, and knee symptoms were obtained, and subjects were examined clinically and radiographically for knee findings of OA. Results. The prevalence of tibiofemoral or patellofemoral OA based on radiographic examination was 3% in shooters, 29% in soccer players, 31% in weight lifters, and 14% in runners (P = 0.016 between groups). Soccer players had the highest prevalence of tibiofemoral OA (26%), and weight lifters had the highest prevalence of patellofemoral OA (28%). Subjects with radiographically documented knee OA had more symptoms, clinical findings, and functional limitations than did subjects without knee OA. By stepwise logistic regression analysis, the risk for having knee OA was increased in subjects with previous knee injuries (odds ratio [OR] 4.73), high body mass index at the age of 20 (OR 1.76/unit of increasing body mass index), previous participation in heavy work (OR 1.08/work-year), kneeling or squatting work (OR 1.10/work-year), and in subjects participating in soccer (OR 5.21). Conclusion. Soccer players and weight lifters are at increased risk of developing premature knee OA. The increased risk is explained in part by knee injuries in soccer players and by high body mass in weight lifters. 相似文献
45.
Enhanced blue fluorescent carbon nitride quantum dots (g-C3N4QDs) were synthesized by a simple solvothermal “tailoring” process from bulk g-C3N4 and analyzed by various characterization methods. The as-obtained g-C3N4QDs were successfully applied in the determination of tetracycline (TC) with a good linear relationship in the range of 0.23–202.70 μM. The proposed fluorescent sensor shows excellent stability, good repeatability, high selectivity and outstanding sensitivity to TC with a low detection limit of 0.19 μM. The fluorescence quenching mechanism of g-C3N4QDs with TC was mainly governed by static quenching and the inner filter effect. The method was successfully applied to monitor TC in tap water and milk powder samples.The g-C3N4QDs were synthesized by a simple solvothermal “tailoring” process from bulk g-C3N4 which have a “strong quenching” behaviour in the presence of TC. The proposed fluorescent sensor has been successfully applied to detect TC in actual samples. 相似文献
46.
为了加强防护剂量监测中的质量控制工作,我们建立了一个用于此目的的剂量学实验室.在X线防护监划、医用诊断X线工作人员剂量与效应研究及医疗照射研究等项工作中,已用这个实验室的条件开展了X线防护仪器的统一刻度,以及个人剂量监测方法比对等项实验工作.本文主要介绍这个实验室的基本条件以及第~次X线防护仪器统一刻度和个人剂量监测方法比对的主要结果. 相似文献
47.
腹腔镜胃癌根治手术自开创至今已经历20余年的发展,随着微创外科理念的不断深入及腹腔镜器械的不断革新,腹腔镜胃癌手术在世界范围已广泛开展。我国虽起步较晚,也取得了长足进步,但腹腔镜胃癌手术的技术水平仍良莠不齐,严重影响临床疗效。笔者就如何做好腹腔镜下胃癌根治术作一概述。提出iFIST理念,即:严格适应证、干净无血术野、腹腔充分灌洗、标本完整、全腹腔镜下手术。 相似文献
48.
Marita Koivunen PhD Maritta Välimäki PhD RN Anita Patel PhD Martin Knapp PhD Heli Hätönen MNSc RN Lauri Kuosmanen PhD RN Anneli Pitkänen MNSc RN Minna Anttila MNSc Jouko Katajisto MSocSc 《Scandinavian journal of caring sciences》2010,24(3):592-599
Scand J Caring Sci; 2010; 24; 592–599 Effects of the implementation of the web‐based patient support system on staff’s attitudes towards computers and IT use: a randomised controlled trial Utilisation of information technology (IT) in the treatment of people with severe mental health problems is an unknown area in Europe. Use of IT and guiding patients to relevant sources of health information requires that nursing staff have positive attitudes toward computers and accept IT use as a part of daily practises. The aim of the study was to assess the effects of the implementation of a web‐based patient support system on staff’s attitudes towards computers and IT use on psychiatric wards. Hundred and forty‐nine nurses in two psychiatric hospitals in Finland were randomised to two groups to deliver patient education for patients with schizophrenia and psychosis with a web‐based system (n = 76) or leaflets (n = 73). After baseline nurses were followed‐up for 18 months after the introduction of the system. The primary outcome was nurses’ motivation to utilise computers, and the secondary outcomes were nurses’ beliefs in and satisfaction with computers, and use of computer and internet. There were no statistically significant differences between study groups in attitudes towards computers (motivation p = 0.936, beliefs p = 0.270, satisfaction p = 0.462) and internet use (p = 0.276). However, nurses’ general computer use (p = 0.029) increased more in the leaflet group than in the IT intervention group. We can conclude that IT has promise as an alternative method in patient education, as the implementation of the web‐based patient support system in daily basis did not have a negative effect on nurses’ attitudes towards IT. 相似文献
49.
Lactase persistence, dietary intake of milk, and the risk for prostate cancer in Sweden and Finland.
Suvi Torniainen Maria Hedelin Ville Autio Heli Rasinper? Katarina Augustsson B?lter Asa Klint Rino Bellocco Fredrik Wiklund P?r Stattin Tarja Ikonen Teuvo L J Tammela Johanna Schleutker Henrik Gr?nberg Irma J?rvel? 《Cancer epidemiology, biomarkers & prevention》2007,16(5):956-961
Prostate carcinoma is the most common cancer in men. Its primary pathogenesis is mostly unknown. Dairy products containing lactose have been suggested to be risk factors for prostate cancer. Digestion of lactose is dependent on lactase activity in the intestinal wall. A single nucleotide polymorphism C to T residing 13,910 bp upstream of the lactase gene has been shown to associate with the developmental down-regulation of lactase activity underlying persistence/nonpersistence trait. To find out whether lactase persistence is related to the risk for prostate cancer, we genotyped 1,229 Finnish and 2,924 Swedish patients and their 473 Finnish and 1,842 Swedish controls using solid-phase minisequencing. To explore if dairy products have an association with prostate cancer, we analyzed the milk consumption in the Swedish study consisting of 1,499 prostate cancer patients and 1,130 controls (Cancer Prostate in Sweden I study) using a questionnaire. Only the consumption of low-fat milk was found to be associated with increased risk of prostate cancer [odds ratio (OR), 1.73; 95% confidence interval (95% CI), 1.16-2.39]. A statistically significantly higher (P < 0.01) lactose intake was observed among subjects with high lactase activity (C/T and T/T genotypes) compared with those with low lactase activity (C/C genotype). Lactase persistence did not associate with increased risk for prostate carcinoma in the Finnish (OR, 1.11; 95% CI, 0.83-1.47; P = 0.488) or in the Swedish populations (OR, 1.16; 95% CI, 0.91-1.46; P = 0.23). In conclusion, lactase persistence/nonpersistence contains no risk for prostate cancer. Analysis of different milk products showed some evidence for low-fat milk as a potential risk factor for prostate cancer. 相似文献
50.
The craniofacial morphology of 48 consecutive adult males with isolated cleft palate was studied by means of lateral cephalograms at the mean age of 18.8 years. Twelve of the patients had received pharyngeal flap surgery between 4 and 12 years of age (mean age 6 years) to improve speech. No significant differences were noticed in craniofacial cephalometric relations between the patients who had not had velopharyngeal flap surgery (VPF-) and those who had (VPF+), although the latter showed a tendency toward a more vertical growth direction. In the pharynx, the VPF+ group showed larger sagittal depths of nasopharyngeal airway but smaller depths of oropharyngeal airway. The differences were significant at the levels of the upper nasopharynx and lower oropharynx. According to the hospital records, none of the patients demonstrated persistent airway obstruction. Cephalometry may be useful in evaluating the changes in pharyngeal airway dimensions that may be related to velopharyngeal flap surgery. 相似文献