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Marin D. E. Pistol G. C. Gras M. Palade M. Taranu I. 《Naunyn-Schmiedeberg's archives of pharmacology》2018,391(10):1147-1156
Naunyn-Schmiedeberg's Archives of Pharmacology - Ochratoxin A (OTA) and aristolochic acid (AA) are toxins that can frequently contaminate cereals and cereals-based products. The present study... 相似文献
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Lisa I. Iezzoni Amy J. Wint Alexy Arauz Boudreau Cheri A. Blauwet Karen A. Kuhlthau 《Disability and health journal》2018,11(3):405-411
Background
Few U.S. studies have explored how children experience a parent's mobility disability and its effects on their daily lives.Objective
We aimed to engage youth ages 13–17 who had at least one parent with mobility disability in describing their perceptions of their parent's disability and its consequences for their daily and family life.Methods
Participants videoed and photographed their experiences following general guidelines from the researchers about topics of interest. Participants made their own choices about what they submitted. We used conventional content analysis to identify broad themes.Results
The mean (standard deviation) age of the 10 participants was 15.2 (1.9) years; 5 were male; 9 participants were white. All 5 girls submitted multiple self-focused (selfie) videos made in their bedrooms; the 5 boys submitted more diverse data files. Several broad themes or topics emerged including: the effects of timing and trajectory of the parent's disability; perceptions of early maturity and responsibility; fears and frustrations relating to the parent's disability; support and emerging resilience; and sense of social justice. Participants generally felt their parents' disability made them become – compared to their peers – more mature, responsible, capable of performing household tasks, and aware of disability civil rights.Conclusions
Participants raised many issues that health care providers should be aware of when youth have parents with mobility disability. A parent's mobility disability may be associated with resilience but also may pose challenges for youth. More research is needed to understand better adolescents' experiences and how clinicians might best assist these youth. 相似文献25.
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Yuliya V. Yushkova Elena I. Chernyak Yuriy V. Gatilov Vladimir G. Vasil&#x;ev Sergey V. Morozov Igor A. Grigor&#x;ev 《Saudi Pharmaceutical Journal》2018,26(1):84-92
The interaction of trolox with ammonia, alkylamines of different classes, and amino derivatives of heterocyclic compounds, including nitroxyl radicals and alkaloids, led to the production of ammonium salts called ion conjugates (ICs). Five ICs were characterised by X-ray diffraction. This is the first time a wide range of ICs were made from trolox with amines, and ESI-MS data demonstrated they have the potential to generate pseudomolecular [(A?B+)?+?H]+ ions. For all obtained trolox ICs, a significant increase (1–3 orders of magnitude) in water solubility was achieved while retaining high antioxidant activity. ICs synthesised from two biologically active fragments may be used to create polyfunctional agents with varying solubility and bioavailability. 相似文献
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