全文获取类型
收费全文 | 1654230篇 |
免费 | 138805篇 |
国内免费 | 6630篇 |
专业分类
耳鼻咽喉 | 21980篇 |
儿科学 | 53400篇 |
妇产科学 | 46781篇 |
基础医学 | 234029篇 |
口腔科学 | 48171篇 |
临床医学 | 148559篇 |
内科学 | 322489篇 |
皮肤病学 | 34566篇 |
神经病学 | 132791篇 |
特种医学 | 66706篇 |
外国民族医学 | 516篇 |
外科学 | 248950篇 |
综合类 | 49987篇 |
现状与发展 | 22篇 |
一般理论 | 545篇 |
预防医学 | 126513篇 |
眼科学 | 38189篇 |
药学 | 127187篇 |
41篇 | |
中国医学 | 6458篇 |
肿瘤学 | 91785篇 |
出版年
2018年 | 16839篇 |
2016年 | 14616篇 |
2015年 | 17707篇 |
2014年 | 23952篇 |
2013年 | 34064篇 |
2012年 | 46606篇 |
2011年 | 49285篇 |
2010年 | 28974篇 |
2009年 | 27491篇 |
2008年 | 45753篇 |
2007年 | 48000篇 |
2006年 | 48837篇 |
2005年 | 47465篇 |
2004年 | 45907篇 |
2003年 | 43885篇 |
2002年 | 42741篇 |
2001年 | 76789篇 |
2000年 | 79503篇 |
1999年 | 67660篇 |
1998年 | 18606篇 |
1997年 | 17147篇 |
1996年 | 16944篇 |
1995年 | 16615篇 |
1994年 | 15578篇 |
1993年 | 14523篇 |
1992年 | 55771篇 |
1991年 | 54061篇 |
1990年 | 52837篇 |
1989年 | 51054篇 |
1988年 | 47426篇 |
1987年 | 46717篇 |
1986年 | 44413篇 |
1985年 | 42940篇 |
1984年 | 32074篇 |
1983年 | 27602篇 |
1982年 | 16161篇 |
1981年 | 14455篇 |
1980年 | 13577篇 |
1979年 | 30469篇 |
1978年 | 21064篇 |
1977年 | 17766篇 |
1976年 | 16694篇 |
1975年 | 17574篇 |
1974年 | 21487篇 |
1973年 | 20674篇 |
1972年 | 18853篇 |
1971年 | 17770篇 |
1970年 | 16289篇 |
1969年 | 15269篇 |
1968年 | 13949篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Loss‐of‐function mutations in the gene encoding filaggrin underlie a Japanese family with food‐dependent exercise‐induced anaphylaxis 下载免费PDF全文
52.
53.
Y.R. Song B. Wu Y.T. Yang J. Chen L.J. Zhang Z.W. Zhang H.Y. Shi C.L. Huang J.X. Pan P. Xie 《Brazilian journal of medical and biological research》2015,48(11):973-982
Bipolar disorder (BD) is a common psychiatric mood disorder affecting more than 1-2%
of the general population of different European countries. Unfortunately, there is no
objective laboratory-based test to aid BD diagnosis or monitor its progression, and
little is known about the molecular basis of BD. Here, we performed a comparative
proteomic study to identify differentially expressed plasma proteins in various BD
mood states (depressed BD, manic BD, and euthymic BD) relative to healthy controls. A
total of 10 euthymic BD, 20 depressed BD, 15 manic BD, and 20 demographically matched
healthy control subjects were recruited. Seven high-abundance proteins were
immunodepleted in plasma samples from the 4 experimental groups, which were then
subjected to proteome-wide expression profiling by two-dimensional electrophoresis
and matrix-assisted laser desorption/ionization-time-of-flight/time-of-flight tandem
mass spectrometry. Proteomic results were validated by immunoblotting and
bioinformatically analyzed using MetaCore. From a total of 32 proteins identified
with 1.5-fold changes in expression compared with healthy controls, 16 proteins were
perturbed in BD independent of mood state, while 16 proteins were specifically
associated with particular BD mood states. Two mood-independent differential
proteins, apolipoprotein (Apo) A1 and Apo L1, suggest that BD pathophysiology may be
associated with early perturbations in lipid metabolism. Moreover, down-regulation of
one mood-dependent protein, carbonic anhydrase 1 (CA-1), suggests it may be involved
in the pathophysiology of depressive episodes in BD. Thus, BD pathophysiology may be
associated with early perturbations in lipid metabolism that are independent of mood
state, while CA-1 may be involved in the pathophysiology of depressive episodes. 相似文献
54.
Improvement in Tricuspid Annular Plane Systolic Excursion with Pulmonary Hypertension Therapy in Pediatric Patients 下载免费PDF全文
55.
56.
57.
患者男,64岁,因头颅增大、面部变长,颧骨隆起、下颌增大、双手掌肥厚、双手指粗短30余年,乳房肿物1年余就诊。患者30余年前无明显诱因出现渐进性手足增大,双手掌肥厚,嘴唇变厚,下颌增大,眉弓及颧骨突出,皮肤增厚,无乳腺增大、泌乳,未诊治…… 相似文献
58.
Yinlei
Wen Huaguang Zhang Hanguang Su He Ren 《Optimal control applications & methods.》2020,41(4):1233-1250
In this article, a model-free off-policy reinforcement learning algorithm is applied to address the optimal tracking problem based on multiplayer non-zero-sum games for discrete-time linear systems. In contrast to the traditional method and the policy iteration method for solving the optimal tracking problems, the proposed algorithm operates with the system data rather than the knowledge of the system dynamics. For performing the proposed algorithm, an auxiliary augmented system is constructed via assembling the original system and the reference trajectory while a discount factor is introduced into the performance indexes. It is analyzed that the solutions of the proposed algorithm converge to the Nash equilibrium and the result is not influenced by the probing noise. Two simulations are presented to verify the feasibility and effectiveness of the proposed algorithm. 相似文献
59.
Osric A. Forrest Daniel M. Chopyk Yael Gernez Milton R. Brown Carol K. Conrad Richard B. Moss Vin Tangpricha Limin Peng Rabindra Tirouvanziam 《Journal of cystic fibrosis》2019,18(1):64-70