全文获取类型
收费全文 | 1557269篇 |
免费 | 103232篇 |
国内免费 | 7581篇 |
专业分类
耳鼻咽喉 | 21238篇 |
儿科学 | 47088篇 |
妇产科学 | 42063篇 |
基础医学 | 209409篇 |
口腔科学 | 42391篇 |
临床医学 | 132166篇 |
内科学 | 300116篇 |
皮肤病学 | 31369篇 |
神经病学 | 124976篇 |
特种医学 | 64015篇 |
外国民族医学 | 487篇 |
外科学 | 241239篇 |
综合类 | 44067篇 |
现状与发展 | 25篇 |
一般理论 | 441篇 |
预防医学 | 113017篇 |
眼科学 | 35800篇 |
药学 | 115451篇 |
43篇 | |
中国医学 | 6969篇 |
肿瘤学 | 95712篇 |
出版年
2018年 | 34477篇 |
2017年 | 27848篇 |
2016年 | 30729篇 |
2015年 | 15587篇 |
2014年 | 20979篇 |
2013年 | 28947篇 |
2012年 | 44151篇 |
2011年 | 59533篇 |
2010年 | 41287篇 |
2009年 | 33316篇 |
2008年 | 54972篇 |
2007年 | 59922篇 |
2006年 | 40713篇 |
2005年 | 40967篇 |
2004年 | 40126篇 |
2003年 | 39953篇 |
2002年 | 37392篇 |
2001年 | 65042篇 |
2000年 | 66887篇 |
1999年 | 56984篇 |
1998年 | 15772篇 |
1997年 | 14571篇 |
1996年 | 13681篇 |
1995年 | 12924篇 |
1994年 | 12151篇 |
1992年 | 43265篇 |
1991年 | 41721篇 |
1990年 | 40999篇 |
1989年 | 39876篇 |
1988年 | 37258篇 |
1987年 | 36634篇 |
1986年 | 35094篇 |
1985年 | 33270篇 |
1984年 | 24915篇 |
1983年 | 21115篇 |
1982年 | 12718篇 |
1981年 | 11601篇 |
1979年 | 23961篇 |
1978年 | 17082篇 |
1977年 | 14843篇 |
1976年 | 13399篇 |
1975年 | 15278篇 |
1974年 | 18101篇 |
1973年 | 17564篇 |
1972年 | 16811篇 |
1971年 | 15721篇 |
1970年 | 14937篇 |
1969年 | 14367篇 |
1968年 | 13479篇 |
1967年 | 12016篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
目的:观察非霍奇金淋巴瘤(non-Hodgkin's lymphoma,NHL)患者自体造血干细胞移植(autologous hematopoietic stem cell transplantation,ASCT)术后应用重组人α-2b干扰素(α-2b IFN)进行早期干预治疗的临床疗效。方法:选取18例行ASCT的NHL患者为研究对象,移植前疾病评估均未达到完全缓解(complete remission,CR),试验组血象恢复后给予IFN 3 000 000 U次/隔日干预治疗,3个月后停用;对照组未行干扰素干预治疗,分析总体疗效及两组对比的生存情况。结果:随访中位时间为34(10~50)个月,患者中位生存时间为37(31~45)个月,3年总体无进展生存(progressive free survival,PFS)、总生存(overall survivial,OS)分别为54.7%、66.8%。ASCT后试验组1年内无疾病复发,2年内复发率为12.5%;对照组1年内复发率为20%,2年内复发率为30%。结论:NHL患者在ASCT后给予重组人α-2b IFN早期干预治疗,患者耐受性好,可能降低移植后早期复发率。 相似文献
23.
Martin R. Späth Malte P. Bartram Nicolàs Palacio-Escat K. Johanna R. Hoyer Cedric Debes Fatih Demir Christina B. Schroeter Amrei M. Mandel Franziska Grundmann Giuliano Ciarimboli Andreas Beyer Jayachandran N. Kizhakkedathu Susanne Brodesser Heike Göbel Jan U. Becker Thomas Benzing Bernhard Schermer Martin Höhne Markus M. Rinschen 《Kidney international》2019,95(2):333-349
24.
Ángel Becerra Héctor Trujillo Lucía Valencia Aurelio Rodríguez‐Pérez 《Brazilian Journal of Anesthesiology》2019,69(2):200-203
Background and objectives
A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.Case report
A 41 year‐old woman suffered a car accident. At the emergency department, no abnormalities were found in ECG or chest X‐ray. Abdominal ultrasound revealed the presence of abdominal free liquid and the patient was submitted to urgent exploratory laparotomy. Nevertheless, she persisted suffering arterial hypotension and metabolic acidosis. Looking for the reason of her hemodynamic instability, intraoperative transthoracic echocardiography was performed, finding out the presence of pericardial effusion. Once the cardiac surgeon extracted pericardial clots, patient's situation improved clinically and analytically.Conclusion
Every anesthesiologist should be able to use the intraoperative echocardiography as an effective tool in order to establish the appropriate measures to promote the survival of patients suffering severe trauma. 相似文献25.
26.
27.
Autoimmune comorbid diseases associated with lichen planus: a nationwide case–control study 下载免费PDF全文
28.
Pradeep Balasubramanian M.D. C. R. Srinivas M.D. Pavai Arunachalam M.S. M.Ch. K. S. Thirumurthy M.S. M.Ch. P. R. Rajkumar M.S. M.Ch. H. Manuvidhya M.B.B.S. 《Pediatric dermatology》2015,32(3):e78-e81
We report on a child with several café au lait spots in association with a lumbar lipomeningomyelocele as an apparently new association. Cutaneous markers, the identification of which plays a crucial role in the early diagnosis and management of spinal malformations, can accompany occult spinal dysraphism. Herein we report a case of lumbar lipomeningomyelocele associated with an overlying café au lait spot that served as a marker of occult spinal dysraphism. The patient also had segmental café au lait spots on the face, making the association unique. 相似文献
29.
Loss‐of‐function mutations in the gene encoding filaggrin underlie a Japanese family with food‐dependent exercise‐induced anaphylaxis 下载免费PDF全文
30.
Seyed Mehdi BagheriMofidi Majid Pouladian Seyed Behnamedin Jameie Ali Abbaspour Tehrani-Fard 《Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine》2016,39(3):717-726
Magnetic field generated by neuronal activity could alter magnetic resonance imaging (MRI) signals but detection of such signal is under debate. Previous researches proposed that magnitude signal change is below current detectable level, but phase signal change (PSC) may be measurable with current MRI systems. Optimal imaging parameters like echo time, voxel size and external field direction, could increase the probability of detection of this small signal change. We simulate a voxel of cortical column to determine effect of such parameters on PSC signal. We extended a laminar network model for somatosensory cortex to find neuronal current in each segment of pyramidal neurons (PN). 60,000 PNs of simulated network were positioned randomly in a voxel. Biot–savart law applied to calculate neuronal magnetic field and additional phase. The procedure repeated for eleven neuronal arrangements in the voxel. PSC signal variation with the echo time and voxel size was assessed. The simulated results show that PSC signal increases with echo time, especially 100/80 ms after stimulus for gradient echo/spin echo sequence. It can be up to 0.1 mrad for echo time = 175 ms and voxel size = 1.48 × 1.48 × 2.18 mm3. With echo time less than 25 ms after stimulus, it was just acquired effects of physiological noise on PSC signal. The absolute value of the signal increased with decrease of voxel size, but its components had complex variation. External field orthogonal to local surface of cortex maximizes the signal. Expected PSC signal for tactile detection in the somatosensory cortex increase with echo time and have no oscillation. 相似文献