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C Del Boca C Ferrari V Zanoni G Dieci G C Grignani R Musci 《Minerva chirurgica》1990,45(18):1165-1169
The Authors discuss a recent case report treated with radial cystectomy associated with a secondary urinary derivation using the caecum-colon reservoir. After having reviewed the various surgical procedures involving the urinary derivations, the Authors describe the technique used by them paying particular attention to the positive aspects of having a low filling pressure reservoir controlled by a valid sphincter ileum-caecum valve. Considering the good postoperative result with this method, the Authors regard this procedure as an alternative to other urinary derivation techniques when carried out with correct indications. 相似文献
94.
Montemurro F Valabrega G Garetto L Aliberti S Grignani G Ortega C Leone F Ponzone R Aglietta M 《Expert opinion on pharmacotherapy》2005,6(16):2907-2921
Nearly 29,000 scientists from all over the world gathered at the 41st Annual Meeting of the American Society of Clinical Oncology (ASCO). The programme included the presentation of new data encompassing all the fields of cancer research, including cancer prevention, treatment and biology. Special sessions were added to summarise and discuss achievements in the field of translational research on biologically targeted therapies. Rational drug design based on tumour biology and genetics represents a promising strategy to overcome the limitations of conventional chemotherapy. Increased knowledge in the field of molecular oncology, genetics and progress in technology are revolutionising tumour classification, prognostication, prediction and therapy. However, at present, for most of the diseases, improvements brought about by the newer therapies are small, although clinically meaningful. This review will briefly address some of the most interesting data presented at ASCO 2005. 相似文献
95.
F Spinozzi R Guerciolini R Gerli I Gernini F Rondoni A Frascarelli P Rambotti F Grignani S Davis 《International archives of allergy and applied immunology》1986,80(4):361-368
Immunologic parameters were evaluated in 22 patients with alcoholic liver disease (ALD). Patients with ALD had increased levels of circulating immune complexes (CIC) and serum immunoglobulins, particularly IgA. The classical complement pathway was preferentially activated in CIC-positive patients. There was no increase in total lymphocyte or total T lymphocyte counts, but a significant rise in both the helper/inducer population (OKT4) and helper/suppressor cell ratio (T4/T8) was noted. The presence of interleukin-2 receptors and HLA-DC/DS and HLA-DR antigens suggested in vivo activation of ALD patients' T cells. The rate of differentiation of B cells to plasma cells was high in both pokeweed mitogen-stimulated and unstimulated cultures of ALD patients' B cells, whereas plasma cell generation doubled when patient T lymphocytes were added to enriched normal B cells. The above data support a role for activated helper (T4+) T cells in the immune response initiated by alcoholic hepatitis. Serum angiotensin-converting enzyme levels and lysozyme levels were increased in ALD patients, and cultured adherent mononuclear cells from ALD patients secreted more lysozyme in vitro than normal cells, suggesting the presence of an activated monocyte-macrophage system in ALD. 相似文献
96.
Giovanni Grignani Lorenzo DAmbrosio Ymera Pignochino Emanuela Palmerini Massimo Zucchetti Paola Boccone Sandra Aliberti Silvia Stacchiotti Rossella Bertulli Raimondo Piana Sara Miano Francesco Tolomeo Giulia Chiabotto Dario Sangiolo Alberto Pisacane Angelo Paolo Dei Tos Luca Novara Alice Bartolini Massimo Aglietta 《The lancet oncology》2018,19(10):1360-1371
97.
Characterization of the Retinoid Binding Properties of the Major Fusion Products Present in Acute Promyelocytic Leukemia Cells 总被引:2,自引:0,他引:2
98.
Caspases Mediate Retinoic Acid-Induced Degradation of the Acute Promyelocytic Leukemia PML/RARalpha Fusion Protein 总被引:13,自引:5,他引:8
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100.
Berger Massimo MD Grignani Giovanni MD Ferrari Stefano MD Biasin Eleonora MD Brach del Prever Adalberto MD Aliberti Sandra MD Saglio Francesco MD Aglietta Massimo MD Fagioli Franca MD 《Cancer》2009,115(13):2980-2987