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Thilo Floerkemeier Jens Gronewold Sebastian Berner Gavin Olender Christof Hurschler Henning Windhagen Gabriela von Lewinski 《International orthopaedics》2013,37(3):369-377
Purpose
The number of candidates for a total hip arthroplasty (THA) is steadily increasing, while the average patient age is decreasing for primary THA. The rise in THA is mainly due to excellent clinical outcomes and the extended longevity of modern implants. Short stem arthroplasties with predominantly metaphyseal fixation such as the Metha® stem are suggested for young patients. It is hypothesised that the more physiological load transfer of these devices reduces stress shielding, which in turn may reduce the risk of aseptic loosening. However, patients with femoral deformities often require a deviation of the resection height. To this end, our aim was to evaluate how resection height influences strain patterns in order to characterise possible limits for short stem implantation.Methods
Biomechanical testing using ten strain gauges on synthetic bone illustrated the strain patterns of three different resection heights (0, +5 and +10 mm) for the Metha stem.Results
The greatest differences in strains were displayed at the “high” (most proximal) resection height (+10 mm) when compared to the non-implanted strain pattern. At the medial calcar, the strain was 143 % for +10 mm, 96 % for +5 mm and 94 % for 0 mm. Overall, discrepancies were less for deeper resections.Conclusions
The deeper the resection, the more similar the strain patterns are when compared to a non-implanted synthetic bone. Changes in strain patterns are induced by variation in the varus/valgus positioning of the implant and by different offsets. 相似文献84.
The classic surgical treatment for symptomatic giant aneurysms originating from the cavernous segment of the carotid artery has been either microsurgical direct clip-reconstruction or carotid occlusion followed by additional cerebral bypass for those patients who fail in a balloon test occlusion. Nevertheless the emergence of new endovascular techniques, especially flow-diverting devices, has promised to revolutionize the treatment of giant cavernous aneurysms, possibly avoiding major microsurgical operations. In this review the authors summarize the current “state-of-art” of treatment of giant cavernous aneurysms, comparing the overall outcomes, complications, morbidity and mortality rates of new flow-diverting devices in relation to traditional microsurgical series. 相似文献
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Divergent Patterns of Social Cognition Performance in Autism and 22q11.2 Deletion Syndrome (22q11DS)
Kathryn L. McCabe Jessica L. Melville Dominique Rich Paul A. Strutt Gavin Cooper Carmel M. Loughland Ulrich Schall Linda E. Campbell 《Journal of autism and developmental disorders》2013,43(8):1926-1934
Individuals with developmental disorders frequently report a range of social cognition deficits including difficulties identifying facial displays of emotion. This study examined the specificity of face emotion processing deficits in adolescents with either autism or 22q11DS compared to typically developing (TD) controls. Two tasks (face emotion recognition and weather scene recognition) were used to explore group differences in visual scanpath strategy and concurrent recognition accuracy. For faces, the autism and 22q11DS groups demonstrated lower emotion recognition accuracy and fewer fixations compared to the TD group. Individuals with autism demonstrated fewer fixations to some weather scene stimuli compared to 22q11DS and TD groups, yet achieved a level of recognition accuracy comparable to the TD group. These findings provide evidence for a divergent pattern of social cognition dysfunction in autism and 22q11DS. 相似文献
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Sanskriti Sasikumar MD Melanie Cohn PhD Irene E. Harmsen BSc Aaron Loh MB BCh BAO Sang Soo Cho PhD Michel Sáenz-Farret MD MSc Ricardo Maciel MD MSc Derrick Soh MD Alexandre Boutet MD PhD Jürgen Germann PhD Gavin Elias BA Ariana Youm MA Katherine Duncan PhD Nathan C. Rowland MD PhD Antonio P. Strafella MD PhD Suneil K. Kalia MD PhD Andres M. Lozano MD PhD Alfonso Fasano MD PhD 《Movement disorders》2022,37(3):635-640
90.
The penetration characteristics of electron beams into x-ray targets are investigated for incident electron kinetic energies in the range 50-150 keV. The frequency densities of electrons penetrating to a depth x in a target, with a fraction of initial kinetic energy, u, are calculated using Monte Carlo methods for beam energies of 50, 80, 100, 120 and 150 keV in a tungsten target. The frequency densities for 100 keV electrons in Al, Mo and Re targets are also calculated. A mixture of simple modeling with equations and interpolation from data is used to generalize the calculations in tungsten. Where possible, parameters derived from the Monte Carlo data are compared to experimental measurements. Previous electron transport approximations in the semiempirical models of other authors are discussed and related to this work. In particular, the crudity of the use of the Thomson-Whiddington law to describe electron penetration and energy loss is highlighted. The results presented here may be used towards calculating the target self-attenuation correction for bremsstrahlung photons emitted within a tungsten target. 相似文献